Correlation between bile duct obstruction and ductal cancer found
...r and that could become good molecular targets for drug therapy. Second, they establish a unique preclinical model of how bile duct cancer in liver progresses that can be used to rapidly test and evaluate novel molecular treatment strategies. Such strategies are badly needed for this understudied can...Anti-fungal drug stops blood vessel growth
...s Hopkins have discovered to their surprise that a drug commonly used to treat toenail fungus can also blo...logy. We couldnt have predicted that an antifungal drug would have such a role. In their search for antiangiogenesis drugs, the researchers worked with ce...Costs of treating arthritis on the rise nationwide, study finds
...re, but pay for a relatively larger share of their drug treatments from their own pockets." From 1997 to 2003, the number of Americans with arthritis or other rheumatic conditions rose 25 percent, due to the aging U.S. population, Yelin said, from 36.8 million adults to 46.1 million. Those numbers corre...Anti-dandruff compound may help fight epilepsy
...y of restoring normal nerve cell activity. Most drug discoveries uncover chemicals that stop things from working - its a lot easier to close or block a door than open it, Li says. But here we found a chemical that makes a defective protein work better. So now we have a chance to actually try to fix the...New blood test can diagnose and monitor treatment of Parkinson's disease
...t, it also opens up new avenues of PD research and drug development. "Further research using this test ...or delay the disease. "The test will also ensure drug trial participants actually have PD so research outcomes will be statistically more valid, which pav...Syphilis rate on rise in US gay, bisexual men
...be going up for several reasons, including illicit drug use and "safe-sex fatigue." In addition, he said, prevention messages might have been "drowned out" by talk about how medications are doing a great job of keeping AIDS patients alive. "Weve been seduced by these amazing drugs and weve fallen behind...Mayo Clinic study finds heart transplant patients benefit from new approach to immunosuppression
...sirolimus, an anti-proliferative immunosuppression drug with potent anti-rejection properties. One study involving 78 heart transplant patients over four years found that gradually transitioning stable patients from calcineurin inhibitors to sirolimus showed consistent improvement of kidney function. T...Decision making by the growing elderly population is uncharted territory
...cularly issues involving Medicare and prescription drug options. In one study, participants were asked to pick the lowest co-payment among four insurance policies. A simple chart showed the plans, monthly premiums and co-payments, but more than 40 percent of 80-84 year olds failed to choose $5 from option...IDSA urges Congress to support Hatch amendments
...from multiple conditions, may in reality be due to drug resistant infections. Antibiotic-resistant bacterial infections kill tens of thousands of Americans every year and can strike anyone, young or old, healthy or chronically ill. It is becoming quite common now for resistant bacterial infections to ...Rush University Simulation Laboratory honored for innovation
...eactions and the effects of biochemical agents and drug overdoses, in addition to surgical and other procedures. "Simulation medical training offers a safe and realistic environment for clinicians to repeatedly practice clinical scenarios and team building skills without subjecting patients to risk," sa...Dopamine-related drugs affect reward-seeking behavior
...into three groups. One group was given levodopa, a drug that increases dopamine levels in the brain. Another took haloperidol, a dopamine receptor blocker. The third was given a placebo. Dopamine is a chemical naturally produced by the body that transmits signals between nerve cells. Researchers showed...New treatment for fungus which causes thrush and sepsis
...n equally effective as the existing treatment in a drug trial. But the new drug has fewer side effects, claims an article published Online and in an upcoming edition of The Lancet....Pharmacists' workload contributes to errors
...combinations of medications that could result in a drug interaction increased by 3 percent for each additional prescription filled per hour. The study also found that computerized interaction alerts and telephone, Internet, and fax systemswhich are intended to decrease pharmacist workload and increase t...Did drug reps encourage doctors to prescribe gabapentin for nonapproved uses?
... that so-called "detail" visits to doctors made by drug company representatives can involve promotion of d...y Parke-Davis between 1995 and 1998 to promote the drug gabapentin. In the USA, before a company can market a drug to doctors for a specific "indication" ...Drug company sales visits influenced doctors, study finds
... company representatives advocating the use of the drug gabapentin led to doctors stating that they intended to increase their prescription of the drug or recommend it to colleagues, according to an analysis of a survey completed by the doctors shortly...Are higher doses of cholesterol drugs worth the extra money? Only sometimes, study says
...wer heart and stroke risk, but higher prescription drug costs and more frequent side effects. Now, a ne...n cost and a range of estimates about how long the drug beneficial effect would last. In general, statin drugs lower the levels of cholesterol in the blo...Drug reps use friendship to influence doctors
...que collaborative paper in PLoS Medicine, a former drug rep and a physician who researches drug marketing reveal the tactics used by drug reps to manipulate physicians into selling drugs. "Drug ...Standard long-acting insulin as good as newer medications
...dies did find that patients treated with the newer drug gained up to 3.5 pounds less than those on NPH. ...Malaria-infected mice cured by 1 dose of new drug
... artemisinin, the active agent in a Chinese herbal drug used to treat malaria and other fevers for thousands of years. Artemisinin comes from the Artemisia annua plant, an herb also known by a variety of names including sweet wormwood. The oxygen-oxygen unit in the peroxides causes malaria parasites ess......rdue University researcher could lead to the first drug treatment for Alzheimer's disease. "There are ma...igned the molecule. "There is an urgent need for a drug to treat this devastating disease, and the scientific community has been working on this problem for...