Rockefeller University researchers are changing the face of drug addiction treatment
People addicted to heroin, alcohol and other drugs of abuse often fail to stay clean because they won't go to or won't stay in treatment. Reporting in the January issue of the Journal of Substance Abuse Treatment , Scott Kellogg, Ph.D., and Mary Jeanne Kreek, M.D., at The Rockefeller University, and...American Thoracic Society Journal news tips for April 2005 (first issue)
...ver the past century, the use of anti-tuberculosis drugs has changed tuberculosis from a disease with a 50 ...ults from those who were treated with tuberculosis drugs at home compared equally well with those treated at a sanitarium. Furthermore, they discovered that ...Top anti-arthritis drugs cause skin disease
Members of the second most important family of drugs used to treat rheumatoid arthritis can cause serio...t for rheumatoid arthritis with TNF-alpha blocking drugs for a period of one to ten years. The drugs the patients had been taking included two anti-TNF-alpha...Study shows new antipsychotic drug prevents brain loss in schizophrenia
...hiatry at Columbia University Medical Center. "The drugs we have for schizophrenia can't cure people who've...ue that we should treat new patients with atypical drugs like olanzapine rather than older conventional medications such as haloperidol and chlorpromazine." ...AACR establishes new lectureship in honor of Dr. Jane C. Wright
...ong the first researchers to test chemotherapeutic drugs in humans which produced effective dosing levels and helped saved lives. Dr. Wright began her pioneering work in 1949, and during her forty-year career she published over 100 research papers on cancer chemotherapy and led delegations of cancer resea...Pezcoller Foundation-AACR International Award for Cancer Research
...f PI3K or downstream effectors. "Indeed, many such drugs are in clinical trials for cancer and are expected to also find use in treatment of inflammatory and allergic diseases." As a graduate student at Cornell University, Cantley studied changes in proteins made by rearranging molecules spatially with...Cognitive therapy works as well as antidepressants, but with lasting effect after therapy ends
..."Medication is often an appropriate treatment, but drugs have drawbacks, such as side effects or a diminished efficacy over time," DeRubeis said. "Patients with depression are often overwhelmed by other factors in their life that pills simply cannot solve. In many cases, cognitive therapy succeeds becaus...Brain region recovery possible in former methamphetamine users
... the underlying physiological changes of stimulant drugs on the human brain."...ACP guidelines to treat obesity cover diet, exercise, drugs and surgery
...cians recommend diet and exercise for everyone and drugs and surgery only for obese patients who are not ab... pressure." Weight-Loss Drugs ACP identifies six drugs that according to valid clinical studies aid weight loss: sibutramine, orlistat, phentermine, diethy...Tip sheet Annals of Internal Medicine, April 5, 2005
...ement recommend diet and exercise for everyone and drugs and surgery only for obese patients who are not ab...sure, diabetes, or sleep apnea. ACP identifies six drugs that, according to valid clinical studies, aid weight loss, but says that the drugs have potential s...Sex hormones hold key to higher rates of abdominal aortic aneurysms in males
...ates these differences, in the hopes of developing drugs that can be used to lower incidence of the life-threatening aneurysms, say Drs. Cassis and Daugherty. Currently no pharmacologic treatments exist with proven efficacy to treat aneurysms. The only existing treatment is surgery when the risk of death ...Differential heart-attack risks among blacks, whites remain mystery
...le to use the information to develop therapies and drugs that reduce heart-attack risks for everyone. In the study, statisticians from Rice University in Houston and medical researchers from The University of Texas Southwestern Medical Center at Dallas conducted a statistical analysis that looked for a rel...ALLHAT findings are 'color blind' in showing diuretics work better for high blood pressure
...s that diuretics rather than newer, more expensive drugs such as ACE inhibitors, calcium channel blockers, ...ed diuretics were as good or better than the newer drugs regardless of race." The study concludes that diuretics are similar to or superior to newer drugs i...Metabolic side effects of antipsychotics are known, but rarely monitored
...hat metabolic problems often associated with these drugs are a substantial concern and that clinicians are ...associated with older antipsychotics. "These newer drugs are definitely more effective, they are just not without their own side effects," Dr. Buckley says. ...Injectable drug, combined with counseling, shows promise in treating alcohol dependence
...ting alcohol dependence. It belongs to a class of drugs called opioid antagonists, for treating alcohol dependence. Although many clinical trials have shown that oral naltrexone can be effective in treating alcohol dependence, its use in clinical practice has been limited, in part because the drug was gi...ALLHAT study findings for racial sub-groups show diuretics work better for high blood pressure
... diuretics are either similar or superior to newer drugs in lowering blood pressure, in tolerability, and in preventing the major complications from high blood pressure. Across both racial subgroups, there was substantially higher risk of heart failure--37 percent--among participants taking calcium channel...Diuretics best initial therapy for both black and nonblack patients in treating high blood pressure
Thiazide-type diuretics remain the drugs of choice for initial therapy of high blood pressure in both black and nonblack patients, according to a study in the April 6 issue of JAMA. Cardiovascular disease (CVD) has become the leading cause of illness and death worldwide, and elevated blood ...Less cognitive impairment seen in women taking drug for osteoporosis
.... Raloxifene is one of the most broadly prescribed drugs for the treatment of osteoporosis (it is also used...s of borderline statistical significance. Like all drugs in its class, known as selective estrogen receptor modulators, raloxifene acts like an estrogen in s...Q Chip helps make cures more effective
...heres. These would allow the effective delivery of drugs to targeted parts of the body. Q Chip makes its uniform particles using tiny capillaries etched in wafers to precisely create micro and nanoparticles. The key advantage of Q Chip's technology is that it can be very accurate about the size, shape and ...Risk of HIV transmission highest in early stage of infection
...eir infection status or receive the antiretroviral drugs used to treat HIV infection. Cohen and Pilcher recommended that increased attention be paid to those recently infected, and that measures such as partner notification, counseling services, and novel biological interventions be developed specifically ...