Sucampo submits new drug application for lubiprostone
...ucampo provided results from two Phase III pivotal efficacy studies, results of a randomized withdrawal (RW) study and three long-term safety studies, including two 12-month safety studies. These pivotal studies demonstrated that lubiprostone produced rapid and sustained effects in treating the symptoms of c...Study shows light therapy to effectively treat mood disorders, including SAD
...ed for review. "We found that many reports on the efficacy of light therapy are not based on rigorous study d...the problem, even slightly?", Golden added. As to efficacy of light therapy for SAD and other non-seasonal depressive mood disorders, Golden said this study la...Cognitive therapy works as well as antidepressants, but with lasting effect after therapy ends
...ve drawbacks, such as side effects or a diminished efficacy over time," DeRubeis said. "Patients with depression are often overwhelmed by other factors in their life that pills simply cannot solve. In many cases, cognitive therapy succeeds because it teaches the skills that help people cope." The research...Different antipsychotic medications may have different effects on brain volume
...ent (olanzapine) that is due to either a safety or efficacy advantage and reflected by a differential pattern of brain volume change and clinical response," the authors conclude. "Future clinical studies should attempt to verify whether the early stage of psychosis is associated with brain volume changes and ...In treatment of depression, cognitive therapy and medication both effective
...ylvania, Philadelphia, and colleagues compared the efficacy of antidepressant medications with cognitive therapy in 240 moderately to severely depressed patients. Study participants were randomly assigned to receive antidepressant medication (n = 120), pill placebo (n = 60), or cognitive therapy (n = 60). Tho...ACP guidelines to treat obesity cover diet, exercise, drugs and surgery
...about potential side effects and lack of long-term efficacy and safety data. (Most weight-loss drugs have no studies beyond one year.) Further, the average weight loss at one year is small to moderate, ACP says, and there are no data on whether weight loss is maintained after drug therapy is discontinued. "Ev...Sex hormones hold key to higher rates of abdominal aortic aneurysms in males
...ntly no pharmacologic treatments exist with proven efficacy to treat aneurysms. The only existing treatment is surgery when the risk of death due to possible rupture of the abdominal aortic aneurysm is judged to outweigh the risk of surgery....Once-a-month injectable medication helps treat alcohol dependence
...ble deaths per year. The drug naltrexone has shown efficacy for treatment of alcohol dependence. However, adhe... and colleagues conducted a study to determine the efficacy and safety of a new formulation, which releases naltrexone for 1 month following a single injection,...Women with heart attacks benefit from stenting
...art attack. The trial investigated the safety and efficacy of stents compared to angioplasty alone in heart attack patients. In angioplasty, a small balloon-tipped catheter is inserted into a blocked artery, and then the balloon is inflated to open the artery. Stenting is performed in conjunction with ang...IOM report should end nevirapine controversy, HIVMA says
...icine (IOM) has reaffirmed nevirapine's safety and efficacy to prevent mother-to-child transmission of HIV. "IOM has confirmed that nevirapine is a valuable tool to prevent mother-to-child transmission in the many places hardest hit by the AIDS pandemic where no other alternative is available," says obstetric...Institute of Medicine news: Review of HIVNET 012 study
...ld revise or retract articles that reported on the efficacy and safety of nevirapine for reducing mother-to-child transmission of HIV based on the HIVNET 012 trial. The Institute of Medicine is a private, nonprofit institution that provides health policy advice under a congressional charter granted to the N...Combination vaccine produces lower immune response than vaccines administered separately
...s targeted for vaccination, with estimated vaccine efficacy of 90 percent. Within 2 years of the introduction of a 7-valent pneumococcal glycoconjugate vaccine into the recommended infant schedule in the United States, there was a 69 percent reduction in culture-positive invasive pneumococcal disease in child...Bugs in the gut could help doctors develop individualised healthcare
...lored more precisely to the individual, maximising efficacy while reducing the risk of an adverse reaction. According to an article published this month in Nature Reviews Microbiology the researchers believe that gut microbes, which influence both the biochemistry and immune system of the host, could play a k...Scientists discover how Ebola virus infects cells
...ors write, "Further investigation of the antiviral efficacy of [enzyme] inhibitors maybe warranted. The wealth of existing knowledge regarding the design and in vivo pharmacology of these inhibitors may facilitate development of an anti-Ebola-virus therapy." The work was done in collaboration with Nancy J. S...Patients' lives at risk from substandard drugs say heart specialists
...ll fibrinolytics, there was a fine balance between efficacy in restoring blood flow to the heart and the risk ...oval was based on short and medium term safety and efficacy as demonstrated through clinical trials. But, once a drug reached the open market, systematic long-t...Early detection of lung cancer
...l participated. Results The research proved the efficacy of this imaging technique for the early-stage dete...of the use of this technique in order to judge its efficacy in the detection of new cancers amongst this population at risk. Moreover, the effect of this monito...Orqis Medical receives unconditional FDA approval for pivotal trial of percutaneous CHF therapy
...esponsive to Medical Therapy) trial will determine efficacy of the Cancion CRS Therapy to treat patients with acute decompensation resulting from CHF. Traditional therapies to treat acute CHF include drugs that pull off fluid (diuretics) or cause the heart to pump more strongly (inotropes). In contrast, the...OHSU study finds ginkgo beneficial for MS symptoms
... be discounted for treating MS, but its safety and efficacy must be tested in much larger clinical trials before doctors should recommend it to their patients. "The study suggests that for cognitive problems, it may only help a certain group of patients," he said. "We need to study this further." And for MS s...Antibiotic might fight HIV-induced neurological problems
...nical research trial first to prove its safety and efficacy against HIV-associated cognitive impairment." SIV and HIV both affect the same tissues in the same way and use the same tricks to infect cells and outwit treatments, but SIV infects only non-human primates, and HIV only infects people. Antiretroviral...Milk thistle does not reduce deaths from liver diseases, best studies find
...disease were excluded. All the trials compared the efficacy of milk thistle or any milk thistle constituent versus placebo or no intervention in patients with liver disease. "There is no evidence supporting or refuting milk thistle for alcoholic and/or hepatitis B or C virus liver diseases," the authors found...