Tag: "estrogen" at medical news
New cause of tamoxifen resistance in breast cancer cells discovered at Lombardi
...r-expression of the spliced variant of the gene in estrogen
receptor-positive breast cancer cells led to reduc... his team found that XBP1 is co-expressed with the estrogen
receptor in breast tumor cells. This may mean that the effects of XBP1 over-expression occur when th...
Low libido in menopause linked to trouble sleeping
... she added, although systemic hormone therapy with estrogen
can reduce vaginal dryness, it can also lower womens natural testosterone, which affects some womens libido. Before starting any drug treatment for changes that happen in menopause, women need to weigh their individual risks and benefits with their...
Benefits of trastuzumab are lasting, reducing both HER2 + breast cancer deaths and recurrence
...ho had HER2 + cancer that was further sub-typed as estrogen
receptor (ER)-negative. So far, 118 patients in the trastuzumab treatment group have developed progressive disease, a second primary cancer or contralateral breast cancer (cancer in the other breast), compared with 243 patients in the chemotherapy gr...
Study finds difference in survival rates among white and black women with advanced breast cancer
...nd 2003. Adjustment factors included: patient age; estrogen
receptor status; and tumor grade. Patients were divided into three subgroups: those diagnosed from1988 to 1993; from 1994 to 1998; and from 1999 to 2003. Overall, the median age of the women was 62 years old; median breast cancer-specific survival ...
MRI detects cancers missed by mammography in breast cancer patients
... to have a common type of tumor, one classified as estrogen
receptor (ER)-positive, says the contralateral breast studys lead investigator, oncology resident Johnny Bernard Jr., M.D., who works with Dr. Vallow. This result mirrors findings of a 969-patient study reported in April 2007 in the New England Journ...
COX inhibitors may weaken protective qualities of estrogen hormone therapy
...ction against heart disease in participants taking estrogen
therapy. The results were described this week in ...lt to identify a cardioprotective effect of taking estrogen
in postmenopausal women. The Penn research group recently found in mice that estrogen
acts via COX-2...
UW study to clarify safety, effectiveness of hormone therapy during menopause
...uctive history to start hormone therapy? How does estrogen
therapy affect a woman's cognition and mood? Wha...de study, the first of its kind, on the effects of estrogen
therapy with perimenopausal women. Led by Sanjay Asthana, head of the UW Section of Geriatrics and...
UC environmental health chair recognized nationally for urologic research excellence
... animals exposed to low doses of the natural human estrogen
estradiol, or the environmental estrogen
bisphenol A (BPA), during fetal development were more likely to develop an early form of human prost...
Estrogen is important for bone health in men as well as women
...es of osteoporosis are numerous, but in women, low estrogen
levels after menopause have been considered an imp... in St. Louis has shown that low amounts of active estrogen
metabolites also can increase their osteoporosis risk. "Most people don't think about estrogen
Impact of a chemical component of diesel exhaust particles
...ion in the PNA and identify whether age, gender or estrogen
alters the presumed effects of PQ. The researcher...all OVX rats (i.e., the young females who had lost estrogen
due to menopausal status), PQ abolished vasodilatation; following the loss of estrogen, particul...
Topical testosterone cream does not increase sexual drive in female cancer survivors
...erapy, and increased libido in women with adequate estrogen
levels. Debra Barton, Ph.D., of Mayo Clinic in ...gative results could be explained by low levels of estrogen
among the study participants. "If providing supplemental estrogen
to women who are postmenopausal...
Other highlights in the May 2 JNCI
...ion Trial found that tamoxifen reduced the risk of estrogen
receptor-positive breast cancer. Umberto Verone...ferent combinations of hormonal therapy, including estrogen
withdrawl, and tamoxifen. A combination of all three HER inhibitors was mor...
Combination treatment stymies breast cancer growth
...n this report, blocking the stimulatory effects of estrogen
on the tumor was also necessary for optimal treatment, said Schiff. Completely blocking the HER pathway is critical, she said. Leaving out just one of the three drugs was much less effective. A clinical study using drug combinations in newly diagnos...
New animal study may explain why alcohol consumption increases breast cancer risk
...sible mechanisms involved include the agitation of estrogen
metabolism and response; cell mutation by the EtOH...el mimics human breast cancer disease in which the estrogen
receptor-positive breast adenocarcinoma cells were subcutaneously injected near the pad of the fourt...
Breastfeeding reduces risk of breast cancer for women who delay childbirth
...hat breastfeeding provides protection against both estrogen
and progesterone receptor positive and negative tu...ct against the type of breast cancers that express estrogen
and progesterone receptors, these factors do not protect against the rarer tumors that do not have t...
Sustainability of energy, food and water theme of ACS national meeting
...ation effective in removing contaminants, reducing estrogen
alterations A study by researchers at the Southern Nevada Water Authority shows that ozone and ozone AOP (advanced oxidation process) are highly effective in the oxidation and removal of many organic contaminants in water and for reducing estrogeni...
Study describes action of estrogen in protecting bone
...ed a novel pathway by which estradiol, the primary estrogen
in humans, aids in maintaining bone density, a fun...l to avoiding osteoporosis. It is well known that estrogen
is essential for healthy bone, and that when the production of estrogen
is reduced, as occurs normal...
New study: Pine bark significantly reduces endometriosis
...24 weeks. (Leuprorelin treatment completely blocks estrogen
in the body and must be discontinued after 24 week...s observed in the Pycnogenol group. Gn-RHa lowered estrogen
levels drastically and in contrast, the estrogen
levels of the Pycnogenol group showed no systematic...
Obesity and environmental chemicals -- New research probes potential link
...ne expression. Does exposure to PBDEs, which mimic estrogen
and thyroid hormones in the body, make cells more likely to develop into fat cells? "Everything I do has to do with how changes in signaling result in changes in gene expression," she says. Careys work is at the cellular level. Isolating the fat t...
Both minor and major ECG abnormalities linked with increased risk of cardiovascular events in women
...ment groups of the Women's Health Initiative (WHI) estrogen
plus progestin trial. This portion of the trial, w...blet containing 0.625 mg of oral conjugated equine estrogen
and 2.5 mg of medroxyprogesterone acetate or a matching placebo. Participants were enrolled from 19...
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