FDA approves ZYFLO CR extended-release tablets for chronic treatment of asthma
... asthma attacks, but can be continued during acute exacerbations of asthma. Leukotrienes are inflammatory mediators in asthma that can trigger asthma symptoms, including inflammation, swelling, bronchoconstriction and mucus secretion. ZYFLO CR uses SkyePharma PLCs (LSE: SKP) proprietary Geomatrix drug delivery t...Clinical trial data for Perforomist Inhalation Solution presented at International ATS Conference
...lar to that of Foradil, and resulted in fewer COPD exacerbations than was seen with placebo. Taken together, the da...or, and the product was associated with fewer COPD exacerbations than placebo. Significantly, repeated testing for cardiac effects showed nothing to suggest a probl...Promising drug fails to improve COPD symptoms
...ce, the transition dyspnea index and the number of exacerbations requiring a doctor or hospital visit. According to the authors, the results of the study were surprising for a number of reasons. Infliximab is an anti-tumor necrosis factor TNF-, and a number of studies have reported increased production of TNF in......PM EST) Patients hospitalized with COPD and asthma exacerbations are likely to have poor glucose control and an ass...xty-seven patients hospitalized for COPD or asthma exacerbations were evaluated for hyperglycemia and a correlation with LOS during corticosteroid treatment. Researc...Asthma linked to soot from diesel trucks in Bronx
...diesel soot particles in air pollution are causing exacerbations of asthma in children," says George Thurston, Sc.D., Associate Professor of Environmental Medicine at NYU School of Medicine, one of the study's principal researchers. The major type of air pollutant that was associated with symptoms of asthma was e...Newsbriefs from the journal Chest: October 2006
...roesophageal reflux disease (GERD), on the rate of exacerbations in 86 patients with COPD (57 percent men, mean age 67.5 years). Patients were recruited from outpatient pulmonary and general medicine clinics, and all completed the Mayo Clinic GERD questionnaire. Researchers defined clinically significant reflux as...Monoclonal antibody reduces exacerbations in asthmatics
... antibody, experienced significantly fewer disease exacerbations than individuals taking a placebo. This research ...ent with infliximab reduced the number of moderate exacerbations in patients with asthma, as monitored by morning and evening use of an electronic spirometer incorpo...Tibotec Therapeutics announces start of largest US study on HIV treatment in women
...ts with known sulfonamide allergy. New-onset or exacerbations of pre-existing diabetes mellitus and hyperglycemia, and increased bleeding in hemophiliacs have been reported in patients receiving protease inhibitors. A causal relationship between protease inhibitors and these events has not been established. ...Inhaled corticosteroids reduce death in patients with COPD
...to multifactorial reasons, including reductions in exacerbations of the disease and suppression of inflammation. Researchers also found a 23 percent reduced risk of death when comparing the effects of inhaled steroids with bronchodilators in patients in the 65+ group. In all cases, the most significant results w...Puerto Rican and African-American children show different patterns of asthma care
...mptoms as they start up, so they don't have severe exacerbations that require emergency visits and hospitalizations," says Woods. "We need to help people understand the idea of taking preventive medication before they're sick." ...Lung diseases represent major costs for society
...e severe, to be followed by an improvement. Severe exacerbations are 60 times more expensive than mild and moderate exacerbations. The indirect costs to society amount to 58% of the total costs of COPD. ...Beta-agonist inhalers more than double death rate in COPD patients, analysis shows
...he anticholinergics, they experienced fewer severe exacerbations requiring hospitalizations and fewer respiratory deaths than those taking only a placebo," said Edwin Salpeter, the J.G. White Distinguished Professor of Physical Sciences Emeritus at Cornell, who led the statistical analysis in the study. An eminent...Literature review highlights options for self-management of asthma exacerbations
...acological strategies for self-managementof asthma exacerbations in adults, including those using inhaledcorticoste...y touse oral corticosteroids (OCS) to treat severe exacerbations and questions whether studies support the common practice of doubling inhaled corticosteroids (ICS) ...May/June 2006 Annals of Family Medicine Tip Sheet
...nts treated with ICSs experienced 33 percent fewer exacerbations than patients on placebo. The reviewed evidence, however, does not show a treatment benefit for patients with mild COPD. Efficacy and Safety of Inhaled Corticosteroids in Patients with COPD: A Systematic Review and Meta-Analysis of Health Outcomes...Inhaled steroids help young children breathe but do not prevent chronic asthma
...roup. They also had a lower rate of severe asthma exacerbations requiring additional treatment with oral corticosteroids and had less need for leukotriene receptor antagonists or additional inhaled steroid treatments. The researchers found that the inhaled corticosteroids appeared to slow the growth of the childr...Uncertainty over give antibiotics in exacerbations of COPD
... has been conflicting evidence as to whether these exacerbations should be treated with antibiotic therapy. A new s...stion whether antibiotics should be used to combat exacerbations of COPD. The uncertainty stems from the growing desire to use antibiotics only when necessary, combi...Wide-spread use of intranasal flu vaccine does not show unexpected serious risks
... study," the authors write. "The reports of asthma exacerbations in vaccinees with prior asthma history highlight t...e need for continued close surveillance for asthma exacerbations following use of this vaccine. The finding of a high proportion of vaccine administration errors and...Experts call for re-focussing of COPD management to reduce hospital admissions and mortality
...ating Chronic Obstructive Pulmonary Disease (COPD) exacerbations is launched today, on World COPD Day. Global diss...rt of the Time to Live Report agreed that reducing exacerbations ("lung attacks") in COPD is vital to improve patients' quality of life and 70% think that reducing h...American Thoracic Society Journal news tips for July 2005 (second issue)
...months. They said that bacteria cause many of the exacerbations which characterize the disease and that such organ...e authors pointed out that 10.2 percent of the 560 exacerbations were likely caused by M. catarrhalis bacteria. According to the authors, for the 20 million adults i...Study shows adherence to pulmicort respules, results in fewer ER visits in asthmatic children
...ar period) to controller therapy had a decrease in exacerbations (23.2% vs 16.8%), while those less adherent had a ...nt to PULMICORT RESPULES therapy had a decrease in exacerbations (25.3% vs 18.6%); while those less adherent did not (20.1% vs. 20.8%). Exacerbation was defined as o...