Oral liquid hydroxyurea promising for long-term use in babies with sickle cell anemia
...Americans. Hydroxyurea increases the production of fetal hemoglobin (HbF), the main oxygen transport protein in fetal red blood cells. Because HbF prevents red blood cells from sickling, clinicians have used hydroxyure...In those genetically predisposed, 'developmental reprogramming' could explain cancer risk
... that exposure to a pharmaceutical estrogen during fetal development can permanently "reprogram" tissue in a way that determines whether tumors will develop in adulthood. While the study was conducted with rats that are susceptible to benign uterine tumors, and the compound used was diethylstilbestrol (DES...Personalized immunosuppression with leading organ transplant therapy may optimize patient care
...l doses on a body surface area basis, it may cause fetal harm when administered to a pregnant woman. CellCept should not be used in pregnant women unless the potential benefit justifies the potential risk to the fetus. Women of childbearing potential should have a negative serum or urine pregnancy test w...Steroid-free regimen with CellCept found comparable to standard therapy in liver transplantation
...l doses on a body surface area basis, it may cause fetal harm when administered to a pregnant woman. CellCept should not be used in pregnant women unless the potential benefit justifies the potential risk to the fetus. Women of childbearing potential should have a negative serum or urine pregnancy test w...Testicular cancer gene in mice may offer clues to origins of cancer in men
...ists in humans that these tumors also arise during fetal development, and this is most likely due to a simi... may also originate from a genetic mutation during fetal development - perhaps by inheritance of a single dead end mutation - and tumor development occurs la...Study finds maternal exposure to parasitic infection may increase risk of schizophrenia in offspring
...xoplasmosis infection is known to adversely affect fetal brain development, this is the first suggestion of a possible association between an elevated maternal antibody to toxoplasmosis and the risk of schizophrenia. "These findings underscore the value of prenatal serologic samples to document how mater...Human eggs can develop from ovarian surface cells in vitro
...ch, and cast doubt on the established dogma on the fetal origin of eggs in adult human ovaries. It is now well established that fetal mammalian eggs originate from somatic stem cells. More recent research of adult human ovaries has s...American Thoracic Society journal news tips for May 2005 (first issue)
... dangerous one, according to the researchers. The fetal lung is particularly sensitive to the effects of m...been estimated to cause five to ten percent of all fetal and neonatal deaths. The problem of smoking mothers also increases the risk of hospitalizations of ...Short sugar chains-a future drug for Alzheimer's?
Heparansulfate, which is needed for normal fetal development among other things, is also important for the build-up of amyloid, morbid protein deposits that appear in several serious diseases. This is shown by Uppsala scientists in an article published in today's Net edition of the U.S. journal Pro...Variant in gene associated with telomeres predicts longer survival of deadly brain tumor
...d in normal cells, it is not generally active past fetal development. Thus, telomeres shorten each time a cell divides, until they cannot protect chromosomes and the cell dies. But in cancer, it is believed that telomerase is activated and intervenes to keep telomeres from shortening, allowing for unlimite...... experienced in a current pregnancy; the impact of fetal loss on the woman's concept of self, and the role of support groups in helping women through a pregnancy after a loss. One of her studies, published in 2003 in the Journal of Obstetric, Gynecologic and Neonatal Nursing, on the influence of perinata...