Tag: "fibrosis" at medical news
'Fickle' enzyme helps protect, but also can promote heart failure, animal study shows
...ss of hypertrophy, showing less muscle growth, and fibrosis
(scar tissue) and better heart function than mice with the enzyme. Normal mice with the gene for NOS3 could not adapt to the stress, leading the researchers to conclude that the enzymes had lost their protective value to the heart during hypertroph...
High blood pressure causes pathological scars in the heart
...a method for the bloodless diagnosis of myocardial fibrosis
and have shown that certain pharmacological treatm...stic means and pharmacological measures to prevent fibrosis
of the heart in these 4 million citizens. Thus, this medical research offers a "message of hope" to ...
Severe sleep apnea may be a risk factor for liver damage
...atosis (fatty liver disease), lobular necrosis and fibrosis
(two signs of liver damage) than patients in the other two groups, regardless of body mass index (BMI), which itself is a known risk factor for fatty liver disease. They also had significantly higher levels of insulin and were more insulin resistant ...
Key milestone in antifungal treatment for severe asthma
...ma sufferers. It could also help those with cystic fibrosis
and chronic sinusitis. Severe asthma in adults aff...ly common, affecting asthmatics, those with cystic fibrosis
and others with chronic sinusitis (usually with nasal polyps). Fungi commonly implicated include ai...
Arthritis of the spine often overlooked in children
... is more prevalent than multiple sclerosis, cystic fibrosis
and Lou Gehrig's disease combined. With new, effective medical options available for AS, early diagnosis and proper medical care can have a significant impact on managing this disease." While back pain is the primary symptom of AS in adults, childr...
Researchers discover novel pathway of inflammation that contributes to lung damage in CF patients
...ients with various lung diseases, including cystic fibrosis
(CF). Their results, which also confirmed this nov...ibute to lung damage in adult patients with cystic fibrosis
(CF), are being published in the July issue of The Journal of Immunology. Jay K. Kolls, MD, who i...
American Thoracic Society Journal news tips for July 2005 (second issue)
...on Bone Health for replacing the vitamin in cystic fibrosis
(CF) patients has been called by researchers who t...ic data to assist in future optimal dosing. Cystic fibrosis
is a life-shortening inherited disorder that affects 30,000 persons in the U.S. Patients who are bo...
Study warns against global use of old asthma medicines for kids' coughs
...from coughing not related to disorders like cystic fibrosis
or asthma. They found four studies, but they were of a limited design, not solid enough to suggest methylxanthine should be used for garden-variety kids' coughs, according to the study. "The Cochrane Review states there is no data to support the use ...
K-State researchers designing better drug to treat cystic fibrosis
...ibrosis. A chronic and progressive disease, cystic fibrosis
is usually diagnosed in childhood. It causes mucus to become thick, dry and sticky. The mucus builds up and clogs passages in the lungs, pancreas and other organs in the body. There is no cure for cystic fibrosis. Management of the disease varies fro...
Biomarkers used to predict recurrent disease in hepatitis C transplant patients
...that up to 20 percent of HCV patients will develop fibrosis
or cirrhosis within two years of undergoing a tran...ld help predict which patients would later develop fibrosis
by using laboratory analysis of alpha smooth muscle actin (alpha-SMA), a reliable marker for HSC act...
Special issue on cystic fibrosis in The Journal of Pediatrics
is a common, fatal genetic disease in which a gene...ed States, approximately 30,000 people have cystic fibrosis
and roughly one child of every 3,500 is born with it. The Journal of Pediatrics has published a spe...
Study proves genetic variations influence cystic fibrosis' severity
...e defective gene known to cause the illness cystic fibrosis
-- can significantly modify the inherited disease'...difiers." Initially, the study involved 808 cystic fibrosis
patients who had inherited an altered form of a gene known as delta F508 from both parents. The seco...
Test predicts risk of liver scarring after transplant, study shows
...ided into two groups: those who developed advanced fibrosis
within two years of liver transplant and those who developed mild or no fibrosis
in the same period. Liver tissue samples from four months, one year and two years post-transplant we...
Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis
...d pediatricians have found that people with cystic fibrosis
exhale higher concentrations of sulfur compounds f...e produced by bacteria, and lung disease in cystic fibrosis
is accompanied by bacterial infections that cause chronic damage. The researchers found that the wor...
Mayo Clinic Cancer Center finds possible genetic link to pancreatic cancer
...fective surgery. Individuals who carry the cystic fibrosis
gene mutation are at increased risk for pancreatit...sis that mutations in the gene that carries cystic fibrosis
may be directly linked to a higher risk for pancreatic cancer. From October 2000 to April 2004, pan...
'Orphan medication' in Europe
...erma is a chronic illness that is characterised by fibrosis
in the skin, blood vessels and internal organs suc...hibitors of TGF Beta 1 may play a key role against fibrosis
and, thereby, in improving sclerodermic conditions. This is why Digna Biotech is developing p144 in...
Little evidence behind bronchodilator therapy for cystic fibrosis
...ity of existing medical trials on a topic. Cystic fibrosis
is a genetically inherited disease afflicting the ...chronic, progressive and ultimately fatal. Cystic fibrosis
causes the exocrine glands, which produce sweat and mucus, to produce thick mucus that clogs the lun...
New clues into causes of scleroderma
...o function failure. It is known that the excessive fibrosis
seen in scleroderma patients is in part the result... much higher doses is an unwanted amplification of fibrosis
and anti-angiogenesis. Since these two processes were not seen at the much lower doses of paclitaxel...
Characteristic cardiac scar pattern predicts risk of fatal arrhythmias
...r excess stress on the heart wall may lead to this fibrosis
and scar formation. "Our study is yet another example of the potential applications of cardiac MRI in the prevention and treatment of cardiovascular disease," says the study's lead author, Saman Nazarian, M.D., a cardiac electrophysiology, clinical a...
American Thoracic Society journal news tips for November 2005 (first issue)
...t who has had two or more relatives with pulmonary fibrosis
since genetic susceptibility plays a significant r...ion persists, the fluid solidifies and scarring or fibrosis
replaces lung tissue. The investigators pointed out that after controlling for the age and sex of ...
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