Community efforts can reduce alcohol fatalities
...otes NIAAA Director Ting-Kai Li, M.D. "This is the first study to explore the effect of the combined use of increased individually-oriented substance abuse treatment and environmental strategies to reduce alcohol availability." Researchers led by Ralph W. Hingson, Sc.D, Professor at the Boston University S...Specific behaviors seen in infants can predict autism, new research shows
...MILTON, ON -- Canadian researchers have become the first to pinpoint specific behavioral signs in infants as young as 12 months that can predict, with remarkable accuracy, whether a child will develop autism. The preliminary findings, published this month in the International Journal of Developmental Neu...VELCADE for injection receives EU marketing authorisation for second-line use in multiple myeloma
...ived at least two prior therapies, VELCADE was the first treatment in more than a decade to be approved for this group of patients. Assessment of Proteasome Inhibition on EXtending (APEX) Remission Results The second line approval is based on the results of the APEX trial (ref 4), an international phase...New insights into HIV immunity suggest alternative approach to vaccines
... Alternatively, we can develop ways to induce that first line of polyspecific antibody defense during vaccination, if these antibodies are not harmful to those being vaccinated," Haynes said. "We now have a window into how to study HIV vaccines from the host side of the problem," he said. Collaborators on ...New prognostic markers help identify risk of relapse
...ute Lymphoblastic Leukaemia (ALL) responded to the first phase of chemotherapy treatment (induction). Dr S... Carcinogenesis Program at CCIA. "Our work is the first to highlight the fact that the differences in the responses of normal and malignant blood cells may ...Obesity in middle age increases risk of dementia in later life
...d late life, say the authors. To date, this is the first study to determine the contribution of mid-life adiposity and skinfold thickness on risk of dementia, they add. If these results can be confirmed elsewhere, perhaps treatment of obesity might reduce the risk of dementia. Failure to contain the prese...Eliminating enzyme dramatically reduces cardiovascular disease
...the effects of ACAT2. This study, reported for the first time today, will be followed by a pilot study in monkeys. Rudel hopes the research will lead to a drug that can inhibit the enzyme's production in humans. Scientists already know that humans produce ACAT2 and that women have lower levels than men. Re...Officials simulate bioterrorist attack to test APL-developed disease surveillance
...en surge in over-the-counter drug sales. It is the first system to integrate military and civilian data. Ea...rams, the NCR disease surveillance system offers a first line of defense in the national capital area. Wednesday's exercise was designed to test the system, ...Breast-cancer risk linked to exposure to traffic emissions at menarche, first birth
...They found that higher exposure around the time of first menstruation to polycyclic aromatic hydrocarbons (... women, higher exposure to PAHs at the time of the first birth was associated with increased risk. Neither association was found in women with a history of ...Fiber supplements may lower cardiovascular risk in type 2 diabetics
...rnative treatment option." The study is one of the first to examine the effect of fiber in cardiovascular risk reduction for people with type 2 diabetes, Verdegem said. The 78 participants in the open label trial had type 2 diabetes and averaged 59 years old. Researchers measured the participants' total...Journal study suggests many glaucoma patients don't take medication properly
...ill rates for two groups of glaucoma patients. The first group takes a single medication for one year witho...econd group delayed refilling prescriptions of the first medication by 5 days or more, and 22 percent waited an additional 15 days or more to pick up their p...Watching metals melt, nanometer-scale views inside cells
...ide planetsand stars, scientists have captured the first atomic-level view ofthe melting process, one of the simplest transformations of matter,on the timescale of femtoseconds, or quadrillionths of a second.Rapidly heating metals and watching how their atoms rearrangethemselves can provide insights into t...Northwestern's cancer genetics program ID's gene variant that increases colon cancer risk
... colorectal cancers," says Dr. Pasche. "That is a first step toward better prevention and treatment of those cancers." Altered genes trigger all cancer. "Most cases of breast, ovarian and colon cancers are caused by damage to the genes that builds up over a lifetime, but some people are born with a high ...Excess oxygen worsens lung inflammation in mice
...ced lung inflammation in three groups of mice. The first group of 15 mice did not receive any supplemental oxygen. While they sustained moderate lung damage, only two died. Another group of 15 mice with acute lung inflammation were treated with either 100 percent or 60 percent oxygen for 48 hours. These mi...UT Southwestern researchers show new drug may help treat certain forms of leukemia
...nzyme, Dr. Ilaria said. "Our study represents the first published characterization of this novel anti-leuk...Hamon Center for Therapeutic Oncology Research, is first author of the Blood study....Exercise training in ordinary people affects the activity of 500 genes
...e probably immensely important. In this study, the first of its kind, Drs James Timmons, Carl J Sundberg and co-workers show that hundreds of genes are activated by regular cycle training for six weeks in young healthy men. Some of these genes are most likely linked to diabetes and cardiovascular disease. ...Mayo Clinic researchers discover genetic glitch in the heart's electrical system
...previously unexplained drownings. Mayo researchers first discovered defects in a gene that causes the heart...olymorphic ventricular tachycardia or CPVT and was first described only 10 years ago. Physicians should consider CPVT in the setting of a suspicious faint du...Simple questions may determine children's exposure to smoke
...n's exposure to tobacco smoke beginning with their first doctor's visit. A simple, quick method for determining the child's risk is needed to facilitate that assessment in busy pediatric practices, the authors suggest. Judith A. Groner, M.D., of The Ohio State University College of Medicine & Public Healt...Medication or psychotherapy effective in treating depressed patients when the other is not
...SP group attended sessions twice weekly during the first four weeks and then once weekly until week 12. If unresponsive to either the nefazodone or CBASP, patients were switched to the other treatment. Of the 156 nonresponders, 140 (89.7 percent) agreed to the crossover therapy. Both the switch from nefa...Too many doctors fail to follow guidelines and to prescribe best treatments for heart patients
...iology journal, the European Heart Journal. In the first large European study to look at the effect of pres...e severity of the patient's symptoms when they are first seen by a doctor and the level of compliance with the guidelines; in other words, the more severe th...