Indiana University Imaging Center receives $6M grant for kidney research
...onjunction with software designed at thecenter use fluorescent molecules to produce detailed quantitative threedimensional images of cells and to analyze activities in living cellswithin the body. The school received its initial O'Brien Center grant of $5 million in2002. Along with research in kidney disease a...Fluorescence diffuse optical tomography provides high contrast, 3-D look at breast cancer
...of fluorophore molecules in tissue that re-radiate fluorescent light after illumination by excitation light of a different color. The reconstructed images demonstrated significant tumor contrast compared to typical endogenous optical contrast in breast.Tumor-to-normal tissue contrast based on FDOT with the fluo...Brightening prospects of using fluorescent nanotubes in medical applications
...INSE) have removed an obstacle that has restricted fluorescent nanotubes from a variety of medical applications, ...t can successfully produce large batches of highly fluorescent nanotubes. Nanotubes have a number of characteristics that make them particularly suitable for use ...UCLA researchers develop new nanomaterials to deliver anti-cancer drugs to cells
...bic anticancer drug camptothecin into the pores of fluorescent mesoporous silica nanoparticles and delivering the particles into a variety of human cancer cells to induce cell death. The results suggest that the mesoporous silica nanoparticles might be used as a vehicle to overcome the insolubility problem of ma...Aluminum foil lamps outshine incandescent lights
...l of Physics D: Applied Physics. Like conventional fluorescent lights, microcavity plasma lamps are glow-discharg...are excited by electrons and radiate light. Unlike fluorescent lights, however, microcavity plasma lamps produce the plasma in microscopic pockets and require no b...Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
...mits researchers to illuminate blood vessels using fluorescent signals, enabling them to see reductions in white cells on the vessel wall and subsequent lessening in inflammation. The scientists also looked at the effects of adiponectin on inflammation in normal mice. They gave mice a substance, TNF-alpha, wh...Scientists develop method to track immune system enzyme in live animals
...olleagues created transgenic mice that had a green fluorescent protein derived from jellyfish fused to the AID en...ellas and coworkers expressed permanently a yellow fluorescent protein in the progeny of germinal center B cells. "Thanks to these new mouse models, we can track i...Fingerprint instead of blood sample
...uently, a second antibody, which was tagged with a fluorescent dye and binds specifically to cotinine antibodies, was applied to the fingerprint. Because there are many cotinine antibodies attached to each nanosphere, there is a significant amplification effect. Indeed, the ridge patterns of smokers fingerprint...Slick and springy: Brown research reveals protein's role in joints
...olecular interaction, researchers put microscopic, fluorescent beads into two samples of synovial fluid. One sample was normal. The other came from a patient whose body doesn't produce lubricin. This rare condition, called CACP syndrome, causes premature joint failure, often prompting the need for joint replacem...Sheffield scientists light up bacteria
...he new method will use a polymer which will give a fluorescent signal when it encounters bacteria, allowing scientists to easily identify infected wounds much earlier than using conventional methodologies. The new technology will be of immediate benefit to healthcare industries in general, as well as those i...Scientists create dual-modality microbeads to improve identification of disease biomarkers
...cal Chemistry. The technology involves embedding fluorescent quantum dots and magnetic iron oxide nanoparticles inside the beads to create dual-modality magneto-optical beads. Nie and Sathe synthesize the quantum dots in different colors by varying their size, giving the beads a unique optical signature. Havin...Physicists set 'speed limit' for future superconducting magnet
...2, with the isotope acting as a probe, much like a fluorescent dye. They then determined the phase diagram of the material where superconductivity is stable, which showed high temperature and high magnetic field could not be achieved together. "Now that we have this information about Bi-2212, the next question...Stem cell activity deciphered in the aging brain
...heir census, the researchers attached easy-to-spot fluorescent tags to the neuronal stem cells in the hippocampus...rting material. The researchers then used another fluorescent molecule to tag all stem cells that were undergoing division in the process of staying "fresh" in ca...Pure carbon nanotubes pass first in vivo test
...D. Anderson. "We are particularly pleased that the fluorescent effect remains intact in our application, because this makes it easier to see where the nanotubes end up, and it opens the door to some exciting diagnostic and therapeutic applications." In a ground-breaking 2002 study, Weisman and colleagues at Ri...Inexpensive test detects H5N1 infections quickly and accurately
...solate, the MChip displays results as a pattern of fluorescent spots. To automate the process of interpreting this pattern--thus eliminating the possibility of human error--the researchers developed an artificial neural network trained to recognize the distinctive pattern indicative of H5N1. Automating the inter...DNA computing targets West Nile Virus, other deadly diseases
...f DNA material that is coded with "red" or "green" fluorescent dye. The computer always makes the first move by activating the center well. Instead of using buttons or joysticks, a human player makes a "move" by adding a DNA sequence corresponding to their move in the eight remaining wells. The well chosen for...OHSU researchers demonstrate how white blood cells cannibalize virus-infected cells
...nse to a systemic viral infection. "If you use a fluorescent dye to stain infected cells, you can literally wat...cently labeled cells, they become labeled with the fluorescent dye themselves," explained Mark Slifka, Ph.D., a researcher in the VGTI who led the research. Slifka...Newly discovered behavior in cancer cells signals dangerous metastasis
...ncer cell would turn, the scientists constructed a fluorescent "reporter" -- a protein that illuminates if the cell turns epithelial but lies dormant if the cell reverts to mesenchymal state. By following the reporter's illumination within cancer cells in rats, the team viewed the very process of alternative sp...Sunscreens can damage skin, researchers find
...activity was detected using a probe molecule whose fluorescent properties change upon exposure to ROS. On comparing images taken before and after the skin was exposed to UV radiation, they found that ROS generation in the skin increased after sunscreen penetration. About 95 percent of the visible signs of agi...... the movement of the proteins visible by attaching fluorescent tags to make them glow when observed under a special microscope equipped with a laser that scanned the cells....