Oral liquid hydroxyurea promising for long-term use in babies with sickle cell anemia
... in the June 14 online edition of Blood. In SCA, a genetic mutation causes oxygen-carrying protein hemoglobin (Hb) to form rigid cords in red blood cells, causing the cells to take on a bent, sickled shape. The sickled cells clog small blood vessels, causing pain and serious damage to the brain, kidneys, spl...Study finds strong link between epilepsy and risk of schizophrenia
...s suggest that the two conditions may share common genetic or environmental causes. The study involved 2.27 m...ors," say the authors. "This finding suggests that genetic or environmental factors shared by family members may have an important role."...A virus-like hitchhiker may trigger bacterial meningitis
...rganism that infects bacteria) inserted into their genetic material. The researchers studied strains of bacteria that had been isolated from humans and found that the strains that carried this virus-like stowaway were more likely to have caused disease. How this bacteriophage causes N. meningitidis to beco...For individuals with family history of lung cancer, risk greater for blacks than whites
...ed at older ages. Researchers have determined that genetic predisposition to lung cancer exists. Approximately 173,770 new diagnoses of lung cancer were estimated to have occurred in the U.S. in 2004. Early-onset cases represent 6.7 percent of lung cancers diagnosed in the U.S. Michele L. Cote, Ph.D., of W...Gene testing doesn't increase anxiety, depression in children of people with Alzheimer's
...e were satisfied and unharmed by the experience of genetic risk assessment, even when results suggested they ... "At the same time, it will be very important that genetic risk assessment is done carefully and communicated accurately so individuals feel empowered by the r...The diagnosis of tumours in children
...vailable in Spanish Determining if there exist genetic alterations that can be associated with the diagno...tled: Molecular diagnosis of neuroblastic tumours: genetic profile and analysis of tumour suppressor genes. Genetic alterations Neuroblastic tumours are mal...Low birth weight of a baby entails risks for the baby's father
...rt by Karolinska Institutet. The report shows that genetic factors affect both birth weight and the risk of c...ar diseases among fathers. This is probably due to genetic factors. "The next step is to conduct more in-depth research to find out which genetic factors may ...Genetic on-off switches pinpointed in human genome
...quence of over 10,000 DNA regions that function as genetic on-off switches, or "promoters" in human fibroblas...but will also serve as a framework for analysis of genetic control in other human cell types, tissues and perhaps organs. The project, detailed in a June 29 el...NIMH study finds antipsychotic Risperidone safe, effective as intermediate term treatment for autism
...to abnormalities in brain development and a strong genetic component. In addition to core symptoms, children with autism frequently exhibit serious behavior disturbances in response to routine environmental demands. For these disturbances, behavior therapy and medications are the two main forms of treatment....Brain function in schizophrenia can improve with support, holds promise for cognitive rehabilitation
...ophrenia. Thus, they may be closely related to the genetic underpinnings of the disorder," said Csernansky, director of the Conte Center. The Conte Center is now looking for more people to take part in its studies, including healthy people, but especially people with schizophrenia and their siblings. For mo...New study examines characteristics of women with an aggressive form of breast cancer
...ors state that finding a molecular determinant and genetic profile for the disease is still needed to "facilitate our understanding of the etiology of this disease, and to identify IBC subtypes that may possess common therapeutic responses and clinical outcomes," they write....Scientists discover how Nipah virus enters cells
...Nipah/Hendra receptor by first sifting through the genetic sequences of 55,000 possible receptors using micro...ntists compared microarray signals from the 55,000 genetic sequences in one set of Nipah virus-resistant human cells with microarray signals from three sets of...MCG faculty contribute to textbooks on geriatric, pediatric hypertension
...rgia Prevention Institute, and Dr. Harold Snieder, genetic epidemiologist, wrote Cardiovascular Reactivity in Youth: Toward a Gene-Environment Model of Stress-Induced Cardiovascular Disease. Dr. Snieder also wrote Familial Aggregation of Blood Pressure. On the other end of the spectrum, "Hypertension in the ...Genomics researchers discover protein deficit that causes drug toxicity
...cs, which tailors medicine to a patient's personal genetic makeup. In the current issue of the Proceedings of.../9394 ) Mayo researchers report that under certain genetic conditions, key proteins are not formed properly -- they are "misfolded." When misfolding happens, t...Size of brain structure could signal vulnerability to anxiety disorders
...ychiatry, notes that future research could look at genetic or environmental factors that may underlie these differences in brain structure and also investigate whether vmPFC size predicts the success of exposure-based therapies for anxiety disorders. Another factor to study would be whether vmPFC measuremen......l to most bacteria. The UCSD team used a molecular genetic approach for their studies, knocking out the genes... as well as in mice engineered to possess the same genetic mutation. Without the oxidant assault, the ability of the nonpigmented strain to resist neutrophil ...Parasite genome sequences offer hope for new drugs and vaccines, Science studies say
...ch were initiated independently, was to decode the genetic blueprint and gain insights into the biology of ea...e marks an important step toward understanding the genetic differences that make other Leishmania species more dangerous information critical for efforts to...Three deadly parasite genomes sequenced
...n 20 laboratories around the globe have determined genetic blueprints for the parasites that cause three dead... in this week's issue of Science. Knowing the full genetic make-up of the three parasites--Trypanosoma brucei, Trypanosoma cruzi and Leishmania major--could le...New discovery may help doctors treat infertility
...le to provide enough information to determine if a genetic mutation may be altering the function of the estrogen receptor beta. The results of this blood test, coupled with information from other medical tests and evaluations conducted by the physician, will help diagnose infertility and better determine tr...Study identifies fat-secreted protein linked to insulin resistance
...says Kahn. Further investigation found that both genetic and pharmacologic elevation of RBP4 can cause insulin resistance and that genetic and pharmacologic decrease of the protein in insulin-resistant states would ameliorate the condition...