Evidence that arsenic was responsible for the madness of King George III
...onarch suffered from acute attacks of porphyria--a genetic defect leading to the faulty synthesis of a protein. However, there is little information available to account for the unusual persistence, severity, and late onset of attacks. One possible explanation is exposure to heavy metals, including lead and ...Gene found in 90 percent of breast cancers may be cancer vaccine target
...turned out to be associated with a rare, inherited genetic disease in which loss of the gene function results in muscle and bone deformities. The gene is located on human chromosome 8 in a region previously known to be associated with breast cancer and other oncogenes. The scientists don't yet know what the ...New finding may aid adult stem cell collection
...tation, is used during the treatment of cancer and genetic blood diseases, such as sickle cell anemia, to restore blood cell formation in bone marrow that has been damaged by high-dose chemotherapy or radiation therapy. It has also shown promise in animal studies for possible treatment of organ damage, such ...Researchers identify gene set linked to breast cancer's spread to lungs
...rs were able to analyze the cells to see how their genetic activity differed from that of breast cancer cells...rcent) of patients whose primary tumors showed the genetic "thumbprint" went on to develop lung metastases, compared with only 10 percent of those whose primar...Anti-inflammatory function of Alzheimer's disease drugs revealed
...lls and can even lead to their death. Furthermore, genetic alterations in the interleukin-1 gene have been associated with increased risk for the appearance and severity of Alzheimer's Disease symptoms. The Hebrew University researchers found that anti-Alzheimer's Disease drugs currently in use not only bl...Researchers model avian flu outbreak, impact of interventions
... poultry, pigs, and people. Scientists fear that a genetic exchange between bird and human flu viruses or the accumulation of H5N1 mutations could soon make efficient person-to-person transmission possible. The avian flu strain represents a particular threat because it is so deadly, said Neil M. Ferguson, ...Family environment is a significant predictor of adolescent obesity
... with adopted adolescents to determine what may be genetic or environmental influences within families that have an obese mother or father. High self-esteem has a positive influence on body weight, and children whose parents received a higher level of education have a decreased risk of being overweight or ob...Report reveals high rate of heart attack amongst ethnic minorities in Scotland
...al factors, barriers to accessing health services, genetic factors and the effects of racism. Raj Bhopal, leader of the project and Professor of Public Health at the University, explained: "Scotland has high quality databases about hospital admissions, but they do not include information about the patient's ...Penn study shows genes may affect response to different quit-smoking medications
...vania School of Medicine indicates that a smoker's genetic make-up may affect whether they quit or not while ...macology. "This study provides new evidence that genetic differences in the brain-reward pathways of smokers may reveal whether they would benefit more from ...Sports doping explored during half-day symposium, Aug. 30
...ng is defined as the non-therapeutic use of genes, genetic elements and/or cells that have the capacity to enhance athletic performance, according to the World Anti-Doping Agency. Experts believe that these scientific advances, although still experimental, will some day be used by athletes to gain a competit...Vitamin D, NSAIDS provide double whammy against prostate cancer, Stanford study finds
...rowth. To get an idea of what calcitriol does on a genetic level to halt tumor growth, the researchers used a...icroarray, a tool that provides an overview of the genetic changes that occur when prostate cancer cells react to calcitriol. The researchers discovered that t...Children's receives one of only two national pediatric rheumatology training grants
...induced arthritis and JRA patients to identify the genetic characteristics of the disease. Of particular impo...elf. Synovial cells then incorporate it into their genetic machinery and begin to make the protein locally." The goal is to achieve steady-state levels of shor...Prevent prostate cancer with antioxidants? Gene pathway may reveal more clues
... gene expression profiling to compare in-depth the genetic makeup of mice whose Nkx3.1 gene was disrupted with that of normal mice. The method takes all DNA from the cells and allows scientists to look for aberrations. DeWeese likens it to studying thousands of pages of an encyclopedia simultaneously; trying...Adult sickle cell drug proves effective in young children
...can Society of Hematology. Sickle cell anemia is a genetic blood disorder that can cause severe pain, fatigue, and organ damage to the kidneys, spleen, and liver. It occurs in about one in every 500 African-Americans. In the new study, 21 children from two to four years old who had sickle cell anemia were gi...New tools used to control foodborne hepatitis A outbreaks related to green onions
Novel use of genetic testing methods helped public health officials con...hepatitis A virus outbreak. The methods, involving genetic sequencing analysis of virus found in blood samples from infected individuals, have greatly improved...Scientists develop screening method for pancreatic cancer
...ysing DNA scientists are able to identify specific genetic mutations that indicate the chances of a patient developing the disease in the short term, ranging from a 0.1% chance to a 90% certainty. Dr Greenhalf added: "Our research has provided strong evidence that anticipation and pancreatic juice analysis...Increased ovarian cancer risk not found in women with breast cancer family history
... of breast cancer but who don't have breast cancer genetic mutations can now be reassured that they are not a...isk of ovarian cancer, they also indicate that the genetic mechanism for up to half of hereditary breast cancer remains unknown. Ongoing research at MSKCC, in ...New online atlas provides collective maps of human brain folds
...g PALS in studies of Williams syndrome, an unusual genetic disorder that produces some cognitive deficits but also makes children hyper-social. "Kids with this condition are very gregarious, and we have previously shown some dramatic differences in the shapes of their brains," Van Essen says. One example o...Definitive gene screen confirms MS suspects
...ple sclerosis (MS), according to the most complete genetic study to date in the disorder, presented at the 13...s, as happens in MS. Researchers believe that some genetic variations in MHC genes make people more susceptible to whatever environmental causes also contribut...Output of e-Science project helps GSK speed up drug discovery
...ng screening molecules for particular activity and genetic research. KDE has been developed for the commercial market by InforSense, a spin-out company from the Department of Computer Science at Imperial College, London. Designed to require little IT knowledge on the researcher's part, it "uses IT to libera...