Metabolic study in mice could lead to 'good cholesterol' boosters
...ed activity of proprotein convertases in the liver gives a significant boost to the protective HDL-C. Proprotein convertases are an unexpected new player in HDL-C metabolism, Jin said. By manipulating levels of the enzyme in both directions, we were able to reduce HDL-C to almost nothing or double it. Th...Parents' depression can weigh on children
..., but factors such as bullying do, she said. It gives a kid language to be able to talk about what it would mean to them to be able to make lifestyle changes, she said, adding that Janickes research helps advance researchers understanding of factors that affect a childs quality of life. Addressing emo...Theory of facial aging gets a facelift from UT Southwestern researchers
...approach facial rejuvenation, Dr. Pessa said. This gives us an algorithm, or scientific approach, to help ascertain what areas of the face may need extra fat to combat the aging process. It also is a major breakthrough in facial anatomy that will have major implications for future studies on aging and poss...New heart disease risk score will help minimize health inequalities
...new score for predicting the risk of heart disease gives a more accurate measure of how many UK adults are at risk of developing the disease and which adults are most likely to benefit from treatment. The study, published on bmj.com on July 6, estimates that in the general population without pre-existin...Holograms make for better vision tests
...rough a series of lenses until they find which one gives each eye the clearest view of a distant target such as an eye chart on a wall. This multi-step process of finding the right lens can be cumbersome and complex. Holography offers many advantages including simplicity, high speed and low cost and could...Paying taxes, according to the brain, can bring satisfaction
...inside the brain, and even measure it. The study gives economists a novel look inside the brain during taxation, said co-author William T. Harbaugh, a UO professor of economics and member of the National Bureau of Economic Research in Cambridge, Mass. To economists, the surprising thing about this paper ...Future therapies for stroke may block cell death
...r of the drug discovery program at UIC. "This work gives us a good direction to follow in testing histone deacetylase inhibitors in animal models for diseases such as Parkinson's and Huntington's disease, and even stroke." Stroke can cause permanent neurological damage or even death if not promptly diagn...Research shows survival benefit for leukemia patients treated with arsenic trioxide
...rapies to fight cancer, not to mention the hope it gives patients and their families. Powell said the willingness of patients with leukemia and their physicians to participate in the clinical trial has markedly improved the outcome for participants and future patients with APL. Study participants under...Brain inflammation may be friend, not foe, for Alzheimer's patients
... genetically engineered a one-of-a-kind mouse that gives him pinpoint control over brain levels of a human molecule known as interleukin-1beta, a well-recognized molecular kingpin in the realm of inflammation. IL-1 beta, a signaling molecule that promotes brain inflammation, was one of the first molecule...Doctors have key role in preventing and detecting child neglect and abuse
...oth sides of the skull. The nature of the fracture gives strong clues, for example the so called bucket handle fracture is usually a sign of abuse. Burns are also frequently due to abuse, whether from deliberate intent from the parent or neglect which has allowed the child to burn itself. When severe h...Once-fatal metabolic disorders treatable, says Stanford/Packard researcher
...es, however. It also protects patients' brains and gives them a chance at a normal life. "Traditionally, the cognitive outcome of these disorders has been horrible," said Enns. "There were ethical arguments to be made about even trying to help these kids. The rationale was 'Why treat if you're going to b...Personality changes may help detect form of dementia
...sease-modifying medications are developed. It also gives the patient and family members more time to plan for the progressive decline." Galvin said more detailed personality tests are not often used in most office settings because of time and lack of training. "Our results show incorporating a brief, sim...Inhaled steroids may not be enough for some children with asthma
...n who have been followed over 10 years. This study gives us a good sense of real-world practice in asthma management, Dr. Sawicki says. The childrens care is not directed by anyone in the study; its an observation of what goes on when the childrens care is directed by their own physicians....Persistent smokers may have higher risk to become depressed than never smokers
...iation of quitting smoking and depressive symptoms gives us indirect evidence on the self-medication hypothesis. Dr. Korhonen emphasizes, however, the further evidence within the same study showing that those smokers who had quit successfully and remained abstinent through the follow-up did not have elevat...Transplanting human gut bugs into mice helps understanding of metabolic system
...s, like those found in some natural yoghurts. This gives us a new way of studying the beneficial effects of probiotics and functional foods and understanding what they do to our "friendly" bacteria. Our new approach allows us to explore which bugs are doing what in metabolic terms, to identify which bugs w...Clinical trial data for Perforomist Inhalation Solution presented at International ATS Conference
...se GOLD criteria. Perforomist Inhalation Solution gives effective, fast bronchodilation that lasts a full 12 hours, allowing patients to nebulize just twice a day once in the morning and once in the evening for convenient, long-term control of their symptoms. And because the product is nebulized, patie...Asthma study shows patients have more options to control disease
...r patients with mild, persistent asthma because it gives them more choices about how to manage their disease," said Stephen P. Peters, M.D., Ph.D., lead author and a professor of pediatrics, internal medicine-pulmonary and associate director of the Center for Human Genomics. The study, involving 500 chil...Smokeless cannabis delivery device efficient and less toxic
...This study demonstrates an alternative method that gives patients the same effects and allows controlled dosing but without inhalation of the toxic products in smoke," said study lead author Donald I. Abrams, MD, UCSF professor of clinical medicine. The research team looked at the effectiveness of a devi...Anxiety hikes risk of heart attack, death
...id. Spending extra time with patients and families gives the cardiologist an opportunity to talk about heart disease, adjust medications, encourage exercise, and come up with effective strategies to improve cardiac risk factors, such as smoking, high cholesterol and high blood pressure. Equally important, ...Breastfeeding duration rates for infants born in an inner-city WHO/UNICEF Baby-Friendly hospital
...eports that being born in a Baby-Friendly hospital gives babies the best possible chance of breastfeeding to 6 months. This is particularly true for low-income populations and for families from backgrounds that traditionally have low breastfeeding rates. The American Academy of Pediatrics, the World Heal...