Landmark study of islet transplantation reveals potential benefits in uncontrolled type 1 diabetes
...insulin, but maintaining improved control of blood glucose levels. After two years, five of these 26 patients...by injection and showed improved measures of blood glucose control and reversal of hypoglycemic unawareness--a condition in which people with type 1 diabetes c...Walking not enough for significant exercise benefits
... markers of overall health, such as fasting plasma glucose levels, response to a two-hour glucose tolerance test and various blood lipids were unaffected by either exercise program. "Our concern is...Study adds to links between sleep loss and diabetes
...wn for some time that skimping on sleep can impair glucose tolerance even for healthy people. Now we have ev...d hemoglobin, or HbA1c, reflects the average blood glucose level over the previous three months. A normal HbA1c result is between four and six percent. Highe...Insufficient sleep associated with poorer blood glucose control in African Americans with diabetes
...-quality sleep may be associated with poorer blood glucose control among African-Americans with diabetes, acc...he ability to respond to the insulin that converts glucose into energy--may contribute to sleep problems. Kristen L. Knutson, Ph.D., of the University of Chic...Drug could prevent type 2 diabetes in high-risk individuals
...s lack of insulin means they are unable to utilise glucose in the normal way. People with two conditions that impair their regulation of glucose - impaired glucose tolerance or impaired fasting glucose - have a high risk of developing type 2 dia...Molecular medicine comes to the rescue
...ain of frequent injections and can help smooth out glucose fluctuations, but still require constant attention...n-producing beta cell. In the normal beta call, glucose metabolism results in increased levels of ATP, a molecule that cells use to store energy. The incre...MRI can track survival of pancreatic islets after transplantation
...d islets and restore normal insulin production and glucose metabolism, several methods of islet transplantation have been developed and tested. One of the most promising called the Edmonton Protocol, since it was developed at the University of Alberta is currently the subject of a multicenter clinical tri...Progression of diabetic retinopathy among African-Americans with diabetes
...ted eye disease was high and related to poor blood glucose control and high blood pressure, according to an a...o energy. Over time, the resulting high levels of glucose in the blood can cause damage to nerves and blood vessels, including those of the eye. Diabetic ret...Pine tree bark reduces diabetic leg ulcers
...tudies show Pycnogenol to be effective in lowering glucose levels and increasing the health of blood vessels in patients with type II diabetes, after supplementation of 50200 mg Pycnogenol. "If left untreated, damage to blood vessels from diabetes then manifests in typical circulatory problems such as hyp...Imaging technique helps predict breast cancer spread before surgery
... all had PET scans, in which a material similar to glucose (fludeoxyglucose F 18, or FDG) was injected into the body along with a chemical tracer. Because cancer cells use more glucose, they absorb more of the FDG. The researchers analyzed the scans to determine the standardized uptake value for each patie...New objective criteria improve PET scan reliability in detecting breast cancer metastasis
...dioactive tracer. Because malignant cells use more glucose than normal cells, FDG accumulates in them and the tracer makes them visible on the PET scan. The key to accurate diagnosis, according to the article, is the amount of tracer uptake a "standardized uptake value" (SUV). At Cedars-Sinai, axillary n...Wear and tear of stress: the psychoneurobiology of aging
...arians, said Epel, tend to show slower insulin and glucose rates when fasting, have higher or similar thyroid hormones and have similar cortisol and growth hormone levels. Even though older adults are exposed to more chronic stressors (more health problems, fewer social connections), they do not necessarily ...JCI table of contents: August 10, 2006
...nt in insulin signaling that controls both fat and glucose metabolism. They show that FoxO1 can have seemingl...sulin sensitivity and fat synthesis in addition to glucose production has the potential to explain the mix of insulin resistance and sensitivity that is common...Chronically high blood sugar linked to risk of cognitive impairment
... them for trials or interventions for better blood glucose control." ...Compound in dairy products targets diabetes
...he cell and interacting with the PPARs to regulate glucose and fat metabolism," says Vanden Heuvel. Early ...s misregulation of insulin and lowers the level of glucose in the blood in patients with adult onset, or Type-2 diabetes, the most common form of this disease....Gout increases risk of heart attack, according to University of Pittsburgh study
...gnificant elevations of blood pressure, age, blood glucose and body mass index were observed in the gout group. Subjects in the group with gout were less likely to be current smokers than were those in the group without gout. During the course of the study, 1,108 events of acute MI occurred in the group wi...Traditional Chinese medicine for diabetes has scientific backing
... been documented in Chinese literature as having a glucose lowering effect when administered to people with diabetes; yet, until now, its mode of action was unknown. Garvan scientist Dr Jiming Ye says: "Our studies in animal models of diabetes show that berberine acts in part by activating an enzyme in the...Message to older adults: embrace, don't fear the effects of sensible exercise
...actors include high blood pressure, elevated blood glucose levels, excess abdominal fat and abnormal cholesterol....Medical device test center expands capabilities to help reduce potential interference
...sion pumps, neurostimulators, cardiac monitors and glucose monitors. And because today's patients may use more than one medical device, the Center has been evaluating possible interactions between different types of devices, such as bone-healing stimulators and implanted cardiac devices. Most recently, th...W.M. Keck Foundation announces 2006 class of Distinguished Young Scholars in Medical Research
...sm through which insulin triggers cells to take up glucose from the blood by modification of a protein complex that activates glucose uptake. Understanding this process at the molecular level could lead to improved treatments for diab...