Pezcoller Foundation-AACR International Award for Cancer Research
...l mechanisms of cellular response to oncogenes and growth factors. It was during this time that his laborat... was produced only when cells were stimulated with growth factors or made cancerous with oncogenes. In addition, genetic evidence indicated that activation o...Angiogenesis factor may help tumors prepare the way for spread to lymph nodes
...the protein VEGF-A, already known to stimulate the growth of blood vessels associated with tumors, also cont...ood supply, a process called angiogenesis, similar growth of new lymphatic vessels was not suspected until 2001. At that time Detmar and his colleagues showe...Scientists discover way to control allergic reactions
...ynthetic peptides into volunteers to stimulate the growth of the regulatory cells, and found the extent of the allergic reaction was reduced. At the same time, this discovery could also have implications for autoimmune diseases such as type 1 diabetes and multiple sclerosis. Autoimmune diseases arise when t...Children's hospital neurologist receives Young Investigator Award in spinal muscular atrophy
...tion of ribonucleic acids (RNA) necessary for axon growth or guidance in motor neurons. To evaluate this hyp...s, he will test whether SMN is required for proper growth of motor neuron axons into their target muscles in chick embryos. He will also identify the RNAs ass...Exposed: Tobacco companies efforts to influence industry privatisation
...ncrease in consumption likely to arise through the growth of advertising and decline in prices effective tobacco control policies, particularly comprehensive advertising bans and adequate taxation rates, should be implemented before privatisation occurs."......ancy. His talk will be "Mutations in the epidermal growth factor receptor as predictors of response to tyrosine kinase inhibitors." AACR Press Room: Location: Room 209, Anaheim Convention Center Hours: Saturday, April 16 Tuesday, April 19, 8:00 a.m. to 6:00 p.m. Wednesday, April 20, 8:00 a.m. to 12:00 no...Tissue engineering experts discuss orthopaedics applications
...re in which laboratory-grown organs and stimulated growth of muscle, bones and nerves could play a major rol...field of orthopaedics, researchers described using growth factors to regenerate bone, using new technologies to enhance the healing of ligaments, efforts to p...Nanotechnology's miniature answers to developing world's biggest problems
...gy self-sufficiency, then the benefits of economic growth will become that much more accessible." Study leader Dr. Fabio Salamanca-Buentello explained that nano-structured materials are being used to build a new generation of solar cells, hydrogen fuel cells and novel hydrogen storage systems that will deli...Chemical library aids in developing drug system for nerve damage
...in, as well as a nerve repair protein called nerve growth factor. Sakiyama-Elbert ran a library of ...teriophage peptides that bound to heparin or nerve growth factor. By repeating this process numerous times, she identified peptide sequences that have low, m...Prostate cancer therapy - study suggests new molecular screening theory
... the journal Nature, that the protein stopped cell growth by inhibiting a crucial oncogene known as TGF beta. As a result of the current study, Smad7 is now thought to play a crucial role connecting the mechanisms of cell growth, governed by TGF beta, and those of cell death, governed by another oncogene, p...Researchers find that chocolate compound stops cancer cell cycle in lab experiments
...l level whether a master switch that triggers cell growth is turned off, or whether the chocolate compound exerts multiple independent effects on diverse cellular processes. That will be the subject of future studies here." Co-authors of the study from Georgetown University are first author Danica Ramijak,...Measuring enzymes at end of cancer pathway predicts outcome of Tarceva, Taxol
...ng cancer cells have a mutation in their epidermal growth factor receptor (EGFR), but that does not predict response to the targeted therapy in other forms of cancer, Ueno says. "We find here that as long as CDK2 is suppressed, the drug works, so developing an accurate test for CDK2 activity would be a boon...Clinical trial of gefitinib for advanced lung cancer closes early
...ormal tissues, that appears to be important to the growth of cancer cells. Based on a review of the limited data available from the Phase III clinical trial, the Data Monitoring Committee overseeing the trial (known as S0023*) recommended the closure, as the trial would not meet its primary endpoint of imp...Spice it up or just veg out, either way you may be helping to defend against cancer
...ncer-fighting benefit by slowing or preventing the growth of cancerous tumor cells. The findings, being pres... inhibition of the protein expression of epidermal growth factor receptor (EGFR). EGFR plays a crucial role in the growth of ovarian cancer cells. PEITC treat...Findings about anti-cancer agent could make it more effective
...ate synthase) that plays a major role in the rapid growth and division of cancer cells. But his recent research shows that the agent also acts on another enzyme (topoisomerase) that helps cancer cells replicate. "Inhibiting topoisomerase causes DNA strands to break, which is an important mechanism that lea...Increasing benefit seen in novel drug that treats Gleevec resistance
...h produces an enzyme that switches on uncontrolled growth in the bone marrow cell. Gleevec binds to this Bcr-Abl enzyme, shutting down its activity, which often leads to death of the leukemia cell. AMN107 is estimated to be up to 30 to 100 times more potent than Gleevec because it was designed to more effic...Nanoparticles offer new hope for detection and treatment
...an inch) wide. Small, rapidly growing tumors cause growth of new blood vessels, which feed the tumors. To get the particles to bind to tumors, the researchers equipped them with tiny "hooks" that link only to complementary "loops" found on cells in newly forming blood vessels. When the nanoparticles hooked ...High levels of immunosuppressant may lead to tumor recurrence
...lants, yet the role of immunosuprressants in tumor growth has not been well established. In a previous study, the authors demonstrated a close relationship between the amount of cyclosporine and tumor recurrence in liver transplant patients. The current study further examines this association and identifie....... Researchers expect this procedure to trigger the growth of new blood vessels to replace damaged ones. The therapy has the potential to augment conventional therapies such as artery bypass grafting and angioplasty. Ateriocyte's unique combination of blood cell types has shown encouraging results in anima......ious types of leukemia and reducing the aggressive growth of breast cancer. The Women's Health Press Confere...ludes new trends in Chinese medicine, new uses for growth hormone replacement therapies, risk factors of polycystic ovary syndrome and treatment for atheroscl...