Tag: "hallmark" at medical news

Metabolic side effects of antipsychotics are known, but rarely monitored

...ation in the brain that causes hallucinations, the hallmark of schizophrenia, by dampening the action of the neurotransmitter dopamine. Somehow in that process of altering brain chemistry, they also make people hungrier and likely alter metabolism, Dr. Buckley says. Whether genetics will one day help a physi...

Exercise slows development of Alzheimer's-like brain changes in mice, new study finds

...f plaque-forming beta-amyloid protein fragments--a hallmark characteristic of Alzheimer's disease (AD)--in their brains. A number of population-based studies suggest that lifestyle interventions may help to slow the onset and progression of AD. Because of these studies, scientists are seeking to find out if a...

Atorvastatin shows promise in small trial for the treatment of mild to moderate Alzheimer's disease

...uction [excess amyloid beta protein deposits are a hallmark of AD] and subsequently the symptoms of AD come from the blood because of increased circulating levels." "Finally, although the results clearly hold promise, this was a pilot proof-of-concept trial with a small number of participants," the authors co...

New strategy for protecting brain against Alzheimer's disease: Enhancing the innate immune system

...d beta, which form amyloid plaques, the definitive hallmark of Alzheimer's disease. Published in the June 10 issue of the Journal of Alzheimer's Disease, the findings could lead to a new approach in diagnosing and treating Alzheimer's disease by helping to diagnose and correct this immune defect. This is th...

Investigating 'brain shrinkage' in alcoholics

...ore affected by immediate than delayed rewards. A hallmark of addictive substances is that they provide an immediate reward in the intoxicating experience. When actively drinking, an individual's inhibition processes become impaired and can further contribute to poor decisions and excessive drinking. With ...

Arteries bio-engineered from elderly cells

...'s own cells. Since unchecked cellular growth is a hallmark of cancer, the researchers also conducted rigorous tests on the arteries and could not detect any signs of unwanted cellular proliferation. Before bio-engineered arteries can be implanted into humans, hTERT expression must be turned off, and arteries...

Understanding and diagnosing an inherited pain syndrome

...tion. Hyperexcitability has long been considered a hallmark of painful neuropathies. Identification of mutations in a specific sodium channel in people with primary erythromelalgia suggests the possibility of rational therapies that target the affected channel. Also, because other pain syndromes, including ...

American Thoracic Society Journal news tips for July 2005 (second issue)

... contribute to the airway inflammation that is the hallmark of the disease. COPD is a term for lung diseases characterized by airflow obstruction that interferes with normal breathing. The two most frequent disease conditions that underlie COPD are severe emphysema and chronic bronchitis. Years of smoking a...

Detecting Alzheimer's in the eye, lifting fingerprints without touching the surface

...at the exact same amyloidbeta proteins which are a hallmark of Alzheimer's disease are alsofound in the lens and its surrounding fluid. In those portions ofthe eye, the proteins form amyloid deposits similar to those in thebrain. Furthermore, the researchers discovered that the amyloidbeta proteins in the l...

Loss of body mass linked to development of Alzheimer's disease

...d rate of cognitive decline, which is the clinical hallmark of AD. Even when controlling for baseline cognitive function, baseline BMI, age, sex, and education, the rate of cognitive decline among people losing approximately one unit of BMI per year was more than 35 percent higher than that of people with no ...

Liver CRP production linked to atherosclerosis

...d by a commentary. C-reactive protein (CRP) is a hallmark of inflammation and tissue damage, as in arthritis or infection. It is also widely touted as a marker for cardiovascular disease, with doctors using patient CRP levels to improve risk assessment. However, whether CRP is merely a risk marker or is a...

Use of pulmonary artery catheterization does not show benefit for severe heart failure patients

...en considered a cornerstone of critical care and a hallmark of the intensive care unit (ICU). Approximately 1 million PACs are used annually in the United States. However, despite widespread use of these devices, there is conflicting data about their effectiveness, and whether they increase risk of illness an...

UNC wins eight top NIH 'Roadmap' grants, more than any other university in the country

...terdisciplinary collaboration has been a long-time hallmark of research at Carolina and a key to success in attracting outside funding. "Our schools and colleges are all located in close proximity to each other, and investigators from different schools have worked productively together for many decades," Juli...

Gene for B-cell development factor might be involved in multiple sclerosis

...to its role in axonal damage. "Axonal damage is a hallmark for multiple sclerosis," write the authors, and EBF is involved in the expression of proteins essential for axonal pathfinding. How axonal damage occurs in MS, however, is not well understood. In their study, Martinez et al. compared the occurrence o...

Backyard treatment may yield leukemia treatment

... uncontrolled production of white blood cells, the hallmark of CML. Patients with the earliest form of the disease called the chronic phase may not even be aware they are sick. If the disease is discovered early, it almost always responds to the drug Gleevec, which puts the brakes on Bcr-Abl activity. The ...

Timing possible treatments against Alzheimer's disease

Alzheimer Disease (AD) is characterized by hallmark lesions called amyloid plaques in the brain. The plaques are formed by the aggregation of small peptides (proteins), called amyloid beta peptide (Abeta), that are produced when a larger protein called amyloid precursor protein (APP) is cleaved by the...

Connective tissue cells from lungs fused with heart muscle to form biological pacemaker

...s that the fused cells can fire spontaneously, the hallmark of pacing cells." While electronic pacemakers work, they have limitations, notes Cho. The device's battery must be changed periodically, a permanent catheter tube must be implanted in the chest to allow access to the pacemaker, and diodes that carry...

Researchers reveals how certain chemicals protect the brain against cell damage

...tance consisting of protein and other materials, a hallmark in the brains of AD patients, may cause cellular death by self-assembling into long protein filaments that are toxic to neurons. It's also possible, Dor said, that prostaglandin protection works by modifying the link between A1-42 and the overproduct...

Insulin levels drop with progression of Alzheimer's disease, linked to tangles in brain

.... They also found that acetylcholine deficiency, a hallmark of the disease, is linked directly to the loss of insulin and insulin-like growth factor function in the brain. The study, published in the November issue of the Journal of Alzheimer's Disease ( http://www.j-alz.com ), is the first to look at insuli...

Groundbreaking guidelines promote early detection

...you about symptoms that they may not appreciate as hallmark signs of poor health. Ask specific questions to define high-risk groups, and initiate early therapy to maintain functional independence and decrease the risk of heart attack, stroke, and death,'" said Dr. Hirsch, an associate professor of epidemiolog...

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Breaking Biology News(10 mins):NYSCF scientists 1 step closer to cell therapy for multiple sclerosis patients 2Invertebrate numbers nearly halve as human population doubles 2Invertebrate numbers nearly halve as human population doubles 3Creating sustainable STEM teacher preparation programs 2
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