Tag: "heparin" at medical news
Chemical library aids in developing drug system for nerve damage
...he could find bacteriophage peptides that bound to heparin
or nerve growth factor. By repeating this process...ces that have low, medium or high affinity for the heparin
drug. Sakiyama-Elbert and her colleagues are looking for protein sequences that bind to dru...
New anti-blood-thinning drug not as safe as protamine
...yme from which heparinase I is derived deactivates heparin
through a mechanism different than protamine. However, the current Phase IIB/IIIA safety and efficacy trial conducted at 47 sites in the U.S, Canada and Germany, was halted early because patients receiving heparinase I had higher incidences of negati...
Two anticoagulant therapies for treating acute coronary syndromes show similar outcomes at one year
...rization strategy and enoxaparin or unfractionated heparin
at the time of hospitalization for ACS had similar...to receive the anticoagulants low-molecular-weight heparin
(enoxaparin) or unfractionated heparin. The primary results at 30 days showed that enoxaparin was at...
Heparin antibodies may pose risk in heart surgery patients
...s who develop antibodies to the anti-clotting drug heparin
nearly double their risk of death or serious compl...Center. "Our study examined whether development of heparin
antibodies before surgery poses an independent risk." The study, which involved 466 patients schedul...
Misdosing common for powerful anti-clotting drugs
...ssociation. The drugs in question unfractionated heparin
(UFH), low-molecular-weight heparin
(LMWH) and glycoprotein IIb/IIIa inhibitors work by either preventing the aggregation of platelets ...
Study finds room for improvement in angioplasty, shows what can be done to cut risks
...de variation in the use of preventive medications, heparin
and dye, and higher rates of some complications than at the five other hospitals. All seven hospitals in the comparison group are now part of the quality-improvement project. "The technology used in these procedures has reached such a point that pat...
Drug-eluting and absorbable stents push interventional frontiers
...ed. The main ACUITY trial was designed to compare heparin
and the direct thrombin inhibitor bivalirudin in 13,820 patients with moderate-to-high-risk ACS. The results were reported on Sunday, March 12, at a Late Breaking Clinical Trial session. The ACUITY Timing Trial was led by Dr. Gregg W. Stone, M.D., ...
Refinements and innovations enhance safety, effectiveness
...rate-to-high-risk ACS to one of three treatments: heparin
(conventional, unfractionated or a low-molecular-weight alternative, enoxaparin) plus GPI, bivalirudin plus GPI, or bivalirudin alone. One month after treatment, investigators measured the net clinical benefit, which balances the risks of ACS itself...
Enoxaparin beats unfractionated heparin as adjunct therapy for heart attacks
...weight heparin, to a strategy using unfractionated heparin
as adjunctive therapy in patients whose primary tr... known as fibrinolytic drugs. Both unfractionated heparin
and enoxaparin inhibit thrombin, a blood protein that plays a key role in the formation of new blood...
Anti-thrombotic medication significantly reduces risk of death for heart attack patients
...icle. Trials of medications such as unfractionated heparin
(UFH), direct thrombin inhibitors, and enoxaparin have thus far failed to demonstrate reductions in the death rate, and bleeding is substantially increased when these agents are used with aspirin and thrombolytic therapy. There is a clear need for an...
Test helps identify patients at low risk for recurring blood clots
...deep veins of the legs or in the lung) consists of heparin
followed by vitamin K antagonists for at least 3 to 6 months. After discontinuation of anticoagulant treatment, a third of patients experience recurrence of VTE within the next 5 to 8 years, according to background information in the article. The cas...
Blood clots can be treated by injections at home
...ess expensive form of the anticoagulant medication heparin
can be just as safe and effective as similar treat...ously (beneath the skin), unfractionated (regular) heparin
was shown in a randomized trial to work just as well as subcutaneous injection of the more expensive...
Less expensive anti-clotting medication appears as safe and effective as more expensive treatment
...ess expensive form of the anticoagulant medication heparin
is as effective and safe as subcutaneous administr... the newer and more expensive low-molecular-weight heparin
for treatment of venous thromboembolism (blood clots in the deep veins of the legs or in the lungs),...
New treatment for severe malaria
... patients." Previously, an anti-coagulant called heparin
was used in the treatment of severe malaria. Heparin was able to release the blood cells, but it was soon withdrawn when it was shown that the substance caused internal bleeding. The new substance is a development of heparin, and has the important di...
New guidelines issued for diagnosis and management of venous thromboembolism
...guideline supports the use of low-molecular weight heparin
for patients with deep vein thrombosis in the outpatient setting when appropriate support services are in place. Each guideline contains several recommendations to aid in the diagnosis and treatment of lower extremity deep venous thrombosis and pulmo...
Embargoed Jan./Feb. Annals of Family Medicine tip sheet
...guideline supports the use of low molecular weight heparin
for patients with deep vein thrombosis in the outpatient setting, when appropriate support services are in place. Each guideline contains several recommendations based on current evidence to clinicians to aid in the diagnosis and treatment of lower ...
Studies highlight advances in diagnosis, medical therapy
...andomly assigning them to one of three treatments: heparin
(conventional, unfractionated heparin
or a low-molecular-weight alternative, enoxaparin) plus GPI; bivalirudin plus GPI; or bivalirudin al...
Study questions risks of anti-bleeding drug during heart surgery
...eart valve surgery, patients receive a drug called heparin
to prevent blood clot formation," Dr. White explai...s are used. If you are using celite-ACTs to guide heparin
dosing in a patient treated with aprotinin, you will think you gave enough heparin
when in fact you ...