Discovery may prevent life-threatening wasting disease in patients with chronic kidney disease
...her researchers found elevated levels of leptin, a hormone that is produced by fat cells and plays a role in weight regulation, may be the cause. Leptin signals through the hypothalamic melanocortin 4 receptor (MC4-R) pathway in the brain, and blocking this pathway may be an important avenue for treatment, t...Diets rich in calcium and vitamin D may decrease risk of PMS
...uggested that calcium supplements and vitamin D, a hormone that regulates the absorption of calcium, may reduce premenstrual occurrence and severity. Elizabeth R. Bertone-Johnson, Sc.D., of the University of Massachusetts, Amherst, and colleagues compared the diets and supplement use of 1,057 women aged 27 t...University of Maryland scientist wins 2005 Kettering Prize
...n postmenopausal women byreducing the level of the hormone estrogen produced by the body, thereby cutting off the fuel that promotes the growth of cancer cells. Unlike other breast cancer drugs that block the effect of estrogen, such as tamoxifen, they inhibit the production of aromatase, an enzyme that pla...Study sheds light on why diabetes drug causes edema
...at the distal nephron, which is usually subject to hormone regulation in the kidney, serves as a key pathway for keeping an accurate amount of sodium in the body. Hypertension affects one in four U.S. adults and long had been considered a cardiovascular disease. But research now also focuses on the kidneys ...Elevated CRP can foil diet's ability to lower cholesterol
...ed 14 men and 18 women, six of whom were receiving hormone replacement therapy. Their LDL cholesterol was in the 124 to 211 mg/dl range. For three weeks, each participant ate only foods on the National Cholesterol Education Program Step 1 diet prepared in the research kitchen. For the next six weeks, the...Thyroid-cancer test reveals recurrence early
...r cells. Patients must then take synthetic thyroid hormone for life. With all thyroid cells eliminated, the ... that patients stop taking their synthetic thyroid hormone several weeks before the test. "That worked fairly well, except that some people became miserable a...Hormone replacement therapy safe for women with menopause & cancer survivors
June 28, 2005 - Research shows that short-term hormone replacement therapy (HRT) is appropriate for peri- and postmenopausal women. These and other results from the Women's Health Initiative (WHI), the largest, most statistically valid and well analyzed research evaluating the use of HRT, are reviewed i...Doctors able to predict potential ovarian failure after radiation
...tland. "This will allow doctors to treat them with hormone replacement therapy and prevent osteoporosis and other disabling symptoms of the menopause. This knowledge will also guide patients and doctors to their future window of opportunity to have a baby. For those young women who are at risk of a very earl...Bone marrow researcher recieves Pew Award
...ed that treating bone-forming cells with a related hormone causes blood cell counts to expand, and survival t...an now explore whether the addition of parathyroid hormone to human cells has the same effect. "Dr. Calvi's work is unique, ambitious and holds great potentia...Steiner symposium brings together leading diabetes experts
... In 1965, Steiner discovered that the double-chain hormone insulin is made in the pancreas as proinsulin, a single chain that doubles back on itself. After proinsulin is secreted, enzymes trim away the segment connecting the two chains to produce insulin. "Proinsulin was the first 'pro-hormone' to be disco...No link found between low androgen levels and low sexual function in women
...t is already known about the intracrine [a type of hormone function] physiology, suggest that sex steroids influence female sexual function, but that there is no serum androgen level that defines female androgen insufficiency. The measurement of serum testosterone, free testosterone, or DHEAS in individuals ...Treatments for prostate cancer may affect employment
...nts vary from removing the prostate by surgery, to hormone therapy, to chemotherapy--each of which may be eff...eiving other treatments, whereas those who elected hormone therapy were more likely to remain working, although the reasons for this difference were not examin...New study shows use of Lorenzo's oil prevents onset of pediatric neurological disorder
...re for X-ALD, and treatment options are limited to hormone therapy and bone marrow transplants. While these transplants can provide important long-term benefits to boys with X-ALD in whom brain involvement is still in the early stages, the procedure carries a significant risk of mortality and morbidity, and...Estrogen, estrogen-like drugs' ability to protect brain after stroke under study
...ional Heart, Lung and Blood Institute, showed that hormone replacement therapy, touted for its ability to reduce the risk of heart attack and stroke in postmenopausal women, appears to increase the risk of those conditions. While Dr. Brann and others still question some aspects of the study, possible ill eff...Women report various symptoms after stopping hormone therapy
Over half of women who began menopausal hormone therapy because of symptoms such as hot flashes or...ts experience those symptoms when they discontinue hormone therapy, according to a study in the July 13 issue of JAMA . Recommended guidelines and prescribin...Other highlights in the July 20 JNCI
...k of breast cancer. The production of melatonin--a hormone that the body produces only during the dark phase of the lightdark cycle--is suppressed by exposure to light during the night. Studies of night-shift workers have found an association between night-shift work (a surrogate for light exposure at night)...Bone-protecting drugs reduce pain and fractures in metastatic breast cancer
...al anti-cancer treatments such as chemotherapy and hormone therapy. There is "strong evidence," adds Pavlakis...oral or intravenous bisphosphonates in addition to hormone therapy or chemotherapy. Fifteen studies comprised 5,187 women with advanced breast cancer and bone ...Secretin should not be used to treat autism, researchers say
The intestinal hormone secretin, considered by some to be a promising dru... studies have since found little evidence that the hormone can improve the key symptoms of the disorder, some people with autistic disorders and their families...New discovery may help doctors treat infertility
...tudies. Years of study have shown that the hormone estrogen plays an important role in a variety of systems, most especially female reproduction. However, it was generally thought that there was only one receptor, the alpha receptor, that responded to estrogen. It wasn't until 1996 that the second r...Study identifies fat-secreted protein linked to insulin resistance
...nd early mortality." Produced by the pancreas, the hormone insulin functions to help cells throughout the body take in glucose and convert the simple sugar to energy. In individuals who are resistant to insulin, the body's muscle, fat and liver cells are unable to properly respond to the hormone, resulting i...