AMPAKINE compounds a new potential treatment for respiratory depression
...a Low impact AMPAKINE drugs, which is currently in human clinical trials, and high-impact molecules which are currently in lead optimization and are currently being tested in transgenic animal models for a variety of neurodegenerative diseases . The two classes of AMPAKINE drugs operate at different bind...New study could bring relief to sweltering city slickers
...y of adapting the urban landscape to bring greater human comfort during hot and sticky spells. The SCORCH... project goals. As well as increasing levels of human comfort, adapting buildings will also help reduce harmful carbon emissions. For example, reducing ...Aluminum foil lamps outshine incandescent lights
...hire. Each lamp is approximately the diameter of a human hair, said visiting research scientist Sung-Jin Park, lead author of the paper. We can pack an array of more than 250,000 lamps into a single panel. Completing the panel assembly is a glass window 500 microns (0.5 millimeters) thick. The windows inne...Medicalizing the human condition
...been transformed. What were once considered normal human events and common human problemsbirth, aging, menopause, alcoholism, and obesityare now considered medical conditions. For b...New drug development facility helps move medicines to market
...cal trials of new drugs, which are required before human trials and subsequent release to the market. Bu...a new cancer treatment that is now being tested in human trials in hospitals around the world. "Australian biotech companies, universities, research insti...MUHC-led international team identifies gene responsible for blindness in infants and children
...vision by RPE65 gene replacement in dogs with LCA, human clinical trials have started in London, UK and in Philadelphia, USA. Preliminary results have been very encouraging and we expect to launch clinical trials investigating gene replacement for CEP290 and LCA5 in the near future, says Dr. Koenekoop. ...GSK's Pazopanib shows positive results in patients with advanced renal cell carcinoma
... and immunotherapeutic regimens using recombinant human interleukin-2 (IL-2) and recombinant human interferon -2b (IFN-), either alone or in combination, have been widely used in patients with advanc...GSK's Pazopanib shows positive results in patients with advanced RCC and ovarian cancer
... and immunotherapeutic regimens using recombinant human interleukin-2 (IL-2) and recombinant human interferon -2b (IFN-), either alone or in combination, have been widely used in patients with advanc...Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
...pletely lacking adiponectin dont exactly mimic the human condition. Most obese individuals, for example, at least have low levels of adiponectin. Part of the work demonstrated that adiponectin also protected against vascular inflammation in normal mice, a result that helps to relate the findings to humans ...Mouse model points to possible new strategy for treating rare muscle disease, kidney disorders
...nd technologies generated by the sequencing of the human genome are being used to uncover new strategies for treating genetic human disease, said NHGRI Director Francis S. Collins, M.D., Ph.D. This work also underscores the value of....... Much more research is needed before any possible human anti-aging drug could emerge, Miller says. Even if this agent turns out to be good for mice, it wont be possible to tell without careful studies of humans whether NDGA is beneficial, useless, or harmful to people. Occasionally, something that is ...GlaxoSmithKline honors cancer research pioneer Gianni Bonadonna with new ASCO Award and Fellowship
...nd students that it is most important to treat the human being and not just the disease. I am grateful to ASCO and GSK for this honor and I hope this Award symbolizes and sends that message to oncology professionals of today and the future, said Dr. Bonadonna....Brain inflammation may be friend, not foe, for Alzheimer's patients
... gives him pinpoint control over brain levels of a human molecule known as interleukin-1beta, a well-recogn...rom experiments with cells in a dish or postmortem human tissue, not from living organisms in which disease progression is closely monitored. People have t...International studies show high efficacy for HPV vaccine
...100 percent effective against the two types of the human papillomavirus (HPV) responsible for most cases of cervical cancerstrains 16 and 18. Results of an international meta-analysis study of the vaccine are published in the June 1 issue of the journal Lancet. In the current and largest study to date, r...Papillomavirus vaccine could substantially reduce cervical cancer incidence
...infection with oncogenic (cancer causing) types of human papillomavirus. Around 500,000 new cases are diagnosed each year, 80% in developing countries, resulting in 250,000 deaths. Dr Kevin Ault, Emory University School of Medicine, Atlanta, Georgia, USA and colleagues from around the world formed the Fu...Human stem cell treatment restores motor function in paralyzed rats
...atory function six weeks after receiving grafts of human spinal stem cells (hSSCs), researchers from the Un...blood flow to the spines neural cells, by grafting human neural stem cells directly into the spinal cord we can achieve a progressive recovery of motor funct...Mercury's link to heart disease begins in blood vessel walls
...y metals and other toxins have been linked to many human diseases, but determining exactly how they damage the body remains a mystery in many cases. New research focusing on a relatively obscure, misunderstood protein suggests mercury's link to heart disease can be traced to activation of this enzyme, whic...Innovative device to treat brain cancer shows promise in early studies
...he results of cell culture, animal and early phase human trials, appears in the current issue of the Procee...ve and safe approach to treating a large number of human cancers." ...Doctors, engineers develop new wireless system to detect esophageal reflux
... that the transmitter can send the results through human tissue. The sensor is designed to detect stomach acid, gas and water so doctors can determine whether the presence of those substances coincides with feelings of heartburn, the start of eating or other activities. The next step will involve testing i...'Nurse cells' make life and death decisions for infection-fighting cells
...ates, with a similar structure and function as the human thymus. Animal thymic tissue sold in butcher shops or at meat counters is known as sweetbread....