The problem with treating spondylarthritis with anti-TNF strategies
...lage. "Our observations strengthen our hypothesis that new bone formation in SpA is clinically relev...m clinical trials are required to corroborate this hypothesis in patients with SpA," he acknowledges, "and to define whether the process of ankylosis should becom...Media coverage of autism differs dramatically
...rs say. One example of flocking came from a 1993 hypothesis that listening to classical music could improve cognitive skills in infants. This finding resulted in a flocking effect by toy manufacturers and parents, and even sparked 1998 legislation in Georgia to distribute classical music CDs to all expecting ...Selenium supplements may contribute to reduced HIV viral load
...ts several possibilities," the authors write. One hypothesis holds that selenium's antioxidant properties may repair damage done to immune cells by oxygen, which is produced at higher levels in the bodies of patients with HIV. However, future research is needed to confirm this relationship. "Given the challe...Does endurance exercise promote life-threatening changes in athletes' hearts?
... right ventricles. The finding adds weight to the hypothesis that endurance sports might contribute to changes ...r evidence to support the second explanation. "The hypothesis that high-level endurance exercise is an underlying cause of the VA is supported by other studies th...Telomere length may predict risk of coronary heart disease in middle-aged men
...most from statin treatmentOur findings support the hypothesis that differences in biological ageing might contribute to the risk--and variability in age of onset--of coronary heart disease"...Scripps research combination therapy obliterates new vessel growth in tumors and retinopathy
...es, but not to combination treatment, supports the hypothesis that compensatory mechanisms might prevent single angiostatics from inhibiting neovascularization," he said. "These results suggest that combination therapy prevents this natural compensation, enhancing the overall anti-angiogenesis effect." In comb...PTSD may increase heart disease risk in older men
...lleagues conducted a prospective study to test the hypothesis that high levels of PTSD symptoms may increase CHD risk, using two different measures of PTSD (the Mississippi Scale for Combat-Related PTSD and the Keane PTSD scale). The authors analyzed data on 1,946 men enrolled in the Veterans Affairs Normative...Researchers show surprising interaction between genes, gender and hypertension
...differences, the researchers set out to test their hypothesis that the influence of genes on blood pressure and hypertension varies with a patient's gender. Ernst Beutler, M.D., of The Scripps Research Institute Department of Molecular and Experimental Medicine, organized a blood sample collection over a two-ye...New dyslexia theory blames 'noise'
...for drug development," saidLu, who is testing this hypothesis with functional magneticresonance imaging trials. ...the [slow processing] ones,are consistent with the hypothesis that ... dyslexic childrenhave difficulty setting their signal filters to optimum andignoring distra...Optical technique provides improved 'virtual biopsies' of internal surfaces
...d with OFDI to further study the vulnerable plaque hypothesis and potentially to diagnose dangerous plaques and guide their treatment. The MGH-Wellman researchers also anticipate extending the technology's capabilities into other fields. "One of the most exciting concepts would be to directly link OFDI with ...Study explores cause of exercise intolerance in heart failure patients
... of patients with diastolic heart failure, but the hypothesis had not been tested. For the current study, researchers examined blood flow in the femoral artery, which delivers a majority of the blood received by the leg. The study involved 30 participants over age 60. Eleven of the participants were healthy,...Ultrasound mammography, volcano monitoring for aircraft safety
...nd perception. The researchers plan to test their hypothesis by predicting how speakers of other languages hear music and other non-linguistic rhythms. (3aPP5; contact John Iversen or Aniruddh D. Patel, The Neurosciences Institute, San Diego, iversen@nsi.edu , apatel@nsi.edu ) ACOUSTICAL VOLCANO MONITORING...Targeted cancer drugs may work by disrupting balance of cellular signals
...their theory, which runs counter to an alternative hypothesis called "oncogene addiction." Better understanding these drugs' mechanism of operation could help surmount current limitations on their usefulness and lead to the discovery of additional protein targets. "It looks like these drugs reduce the activ...Mayo Clinic researchers find evidence for traumatic cause of carpal tunnel syndrome
...ial motion of adjacent digits, and may support the hypothesis of a traumatic cause for carpal tunnel syndrome," he says....Some factors related to heart function and linked with heart failure more common than believed
...t without HF in the same community, supporting the hypothesis that diastolic dysfunction is present in a large segment of patients presenting with HF and preserved EF. Similarly, the high prevalence of moderate and severe diastolic dysfunction in patients with HF and reduced EF supports the importance of diasto...Canadian study demonstrates medical induction of labor increases risk of amniotic-fluid embolism
...ion or uterine rupture. "Our findings confirm the hypothesis that medical induction of labour is related to an increased risk of AFE," added Dr. Kramer. "Although the absolute risk increase of AFE for women is very small (four or five total cases and one or two fatal cases per 100,000 women induced) and is unl...Mayo Clinic study could lead to safer pesticides
...s pesticides developed decades ago is based on the hypothesis that these pesticides are used in low doses that humans can tolerate, but pests cannot," Dr. Pang says. But according to a report by the Environmental Protection Agency's Office of Inspector General, some anticholinesterase pesticides can enter the ...New treatment for post-concussion syndrome pioneered at UB
...hs post-concussion. Their regimen is based on the hypothesis that the regulatory system responsible for maintaining cerebral blood flow, which may be dysfunctional in people with a concussion, can be restored to normal by controlled, graded symptom-free exercise. "The treatment program is well tolerated by p...Penn researchers find psoriasis patients at increased risk for heart attack
...ners in the United Kingdom who were unaware of the hypothesis being tested. The data was collected as part of the patient's electronic medial record and maintained in the General Practice Research Database. The study population consisted of psoriasis patients aged 20-90. Among these patients, 127,139 were ...Mouse study reveals new clues about virulence of 1918 influenza virus
...to lung tissues. This observation gave rise to the hypothesis that the 1918 flu virus infection provoked an uncontrolled inflammatory response leading to rapid lung failure and death. To test this idea, Dr. Tumpey infected mice intranasally with one of four types of flu virus: human seasonal flu virus from a...