Pesticide exposure associated with incidence of Parkinson's disease
...nd motor abnormalities. "The findings support the hypothesis that exposure to pesticides is a risk factor for Parkinson's disease," the authors conclude. Since this study did not have access to information on specific pesticides, they suggest, "future studies should seek to identify the specific compounds asso...Queen's-led network looks at FAS aiming to minimize life-long learning problems
...understand the underlying mechanisms of this novel hypothesis of FASD, the Toronto team members are studying the effects of formic acid and folic acid on the biological functions and survival of neurons in isolated brain tissue. In parallel studies, the Kingston team will assess the efficacy of folic acid suppl...Participation in clinical trials does not appear to affect physician's adherence to guidelines
... practices by 6.7 percent. "Our study confirms the hypothesis that physician involvement in clinical trials is a powerful tool for influencing company-specific drug preferences. Several mechanisms may be responsible, including setting up a gift relationship by payment to the trial-conducting physicians. If we h...Study looks for genetic predictors of hypertension
...r hypertension risk in the general population. "My hypothesis is if Liddle syndrome is caused by these nasty, dr... stress is a sign of what's to come. If Dr. Dong's hypothesis holds, young people with risky genetic variations could have advance warning of their increased hype...Wild vs. lab rodent comparison supports hygiene hypothesis
...chieve or considered less critical. The prevailing hypothesis concerning the development of allergy and probably... is the hygiene hypothesis," Parker said. But this hypothesis has not been thoroughly tested in animal studies, he said, and the few studies conducted have focuse...Encouraging results for folic acid as a cancer prevention drug
...ificantly. This study provides data to support the hypothesis that folate insufficiency is a risk factor for cancer progression. Folate deficiency is the most common vitamin deficiency in the United States. Folate is a naturally occurring B vitamin (B-9) found abundantly in fresh vegetables and fruits. Folic a...Abnormal glucose metabolism may contribute to chronic nerve disorder
... previous studies, this investigation supports the hypothesis that distal axonal polyneuropathies may occur in much earlier stages of abnormal glucose metabolism than previously thought. Recent studies suggest that the neuropathy associated with impaired glucose tolerance may be milder than neuropathies tradit...Transporter is possible target for safer pain medicine
... review for funding of novel ideas to pursue this hypothesis as well as the molecular analysis of the transporter. The idea that a transport system is involved is itself a novel concept. Conventional wisdom was that an enzyme was responsible for hydrolyzing, or decomposing, opioid peptide, Dr. Ganapathy says. ...Drug attacks prostate cancer in mouse model by destroying its blood supply
...dings are a vibrant example of the "seed and soil" hypothesis in metastasis - the deadly spreading of a cancer from its organ of origin to other organs, a process that kills 90 percent of all patients who die from their disease. In landmark findings, Fidler and colleagues demonstrated that the vast majority of ...New understanding of Ewing's sarcoma suggests novel treatment strategy
...or treatment," Toretsky said. To find out if their hypothesis was true, the research team utilized a virus that displayed random, but identifiable, protein sequences and mixed the viruses with EWS-FLI1. "We wanted to see what viruses stuck to the EWS-FLI1 protein," Toretsky said. They found a certain peptide se...Exploring the potential of cholesterol-lowering drugs for patients with systemic sclerosis
...share the results of an experiment to affirm their hypothesis and test a novel treatment strategy. Their objective: to determine the effectiveness of one of the most popular and potent cholesterol-lowering drugs atorvastatin, marketed under the brand name Lipitor for increasing blood flow and improving th...Inconsistent access to food in low-income households may contribute to weight gain
...but not as pronounced as they were for women. One hypothesis for why there is a contradictory relationship between weight and income, Wilde says, is that, "gradual weight gain may occur from inconsistent access to food, leading to periods of underconsumption followed by compensatory overconsumption. Alternativ...Worsening anemia signals poorer outcomes in men treated for advanced prostate cancer
...ry by race." Beer and his colleagues tested this hypothesis in a retrospective analysis of SWOG 8894, a randomized study of orchiectomy versus orchiectomy plus flutamide in previously untreated metastatic prostate cancer. Of the 1,286 subjects enrolled in SWOG 8894, data from 817 subjects were available f...Witnessing intimate partner violence as children does not increase risk of victimization as adults
...esults of this study did not, in fact, support the hypothesis that Adult Child Witnesses (Adult-CWs) were more likely to become adult victims of IPV. Correlation of Adult-CWs with IPV was not statistically significant, with 32% of Adult-CWs and 21% of the non-Adult-CWs positive for IPV. Adult-CWs were 4 times ...Long airplane flight does not appear to increase risk of blood clots
...ding to background information in the article. One hypothesis has been that hypoxia (reduced oxygen in the blood...). "In conclusion, our findings do not support the hypothesis that hypobaric hypoxia of the degree that might be encountered during long-haul air travel is associ...Europe wide study to examine causes of asthma
...cale of GABRIEL will allow us to properly test the hypothesis and to identify the responsible agents." GABRIEL will also develop model systems to investigate the molecular basis of genetic and environmental interactions which influence asthma, and use these model systems to translate novel findings into means ...Italian researchers find fenretinide cuts the risk of second breast cancers in young women
...l study was planned, so our findings are therefore hypothesis generating. It means that we are not in a position to make clinical recommendations from these data alone, but that this evidence provides a rationale for a new trial in young women at high risk of breast cancer. However, the magnitude of the effect,...Simple formula predicts blood needs in heart surgery
...s on the last third of patients. "We confirmed our hypothesis that a model based on a patient's characteristics prior to surgery could predict how much blood would need to be cross-matched prior to surgery," Lappas said. "This approach would appear to be a more rational and scientifically based approach for pre...Does IQ drop with age or does something else impact intelligence?
...ab during two coding experiments to test out their hypothesis that older people suffer perception problems that ... task. This finding offers direct support for the hypothesis that sensory deficits influence coding task performances," stated the researchers. The testing of th......U Sleep and Mood Disorders Lab set out to test the hypothesis that circadian physiological rhythms become misaligned with the sleep/wake cycle during the short days of winter, causing some people to become depressed. Usually these rhythms track to the later dawn in winter, resulting in a circadian phase delay w...