New insights into the impact of injury on cartilage cells
... Texas, present the results of a study to test the hypothesis that leukocytes extend the zone of damage and cell death in cartilage after an acute injury. The research team began with a collection of dog bones--the hind knee joints of 24 fresh young adult cadaver canines. With...Scientists discover possible link between oxidative stress and non-hereditary degenerative disease
...on levels of the protein in sporadic cases. Their hypothesis that DJ-1 was the missing link proved to be correct: DJ-1 in patients who had Parkinson's disease showed signs of oxidative damage, including structural changes as the protein accumulated additional oxygen molecules (carbonylation and methonine oxida...MIT research offers new hope for Alzheimer's patients
...sed the cognitive decline. But the failure of this hypothesis to lead to an effective treatment for Alzheimer's ...neuronal cell membranes. That further supports the hypothesis that omega-3 fatty acids increase synaptic membrane formation, said Wurtman. Alzheimer's patients in...Adherence to treatment guidelines for patients with ACS associated with decreased in-hospital deaths
... the authors write. "Our work supports the central hypothesis of hospital quality improvement; namely, better adherence with evidence-based care practices will result in better outcomes for patients who are treated."...Latest issue of Alzheimer's & Dementia explores new ideas for cause, screening and risk factors
...nders present an alternative theory to the amyloid hypothesis for the cause and progression of Alzheimer's disea...ed risk factor for late-onset Alzheimer's. The new hypothesis is supported by the results of 24-week randomized clinical trial of an unmarketed formulation of ros...Markers of PCOS inherited, persist and raise risk for heart disease, diabetes
...versity College of Medicine, Hershey, tested their hypothesis that abnormal lipid levels are inherited in families of women with PCOS, and assessed the impact of age on reproductive and metabolic characteristics. The researchers studied 215 non-Hispanic white mothers of women with PCOS and a control group of...Periodontal therapy may help diabetic patients improve sugar control
Chicago Results of a new study support the hypothesis that periodontal therapy may improve metabolic control (lower HbA1c) in diabetic patients. This study appears in April's issue of the Journal of Periodontology. The results suggest that periodontal therapy may reduce a diabetic patient's HbA1c count...ISHLT celebrates 20th anniversary of infant cardiac transplantation
... per year receive heart transplants. Dr. Bailey's hypothesis that infants' immature immune systems would make them more likely to accept transplanted organs than older patients is supported by years of research and studies in pediatric transplantation. The ISHLT Pediatric Registry shows that patients transpla...Soy intake associated with reduced risk of breast cancer
...cer risk. Some of these studies were based on the hypothesis that Asian women have reduced incidence of breast cancer, compared to American women, because they have traditionally eaten a diet rich in soy foods, such as tofu. In some studies, soy foods were just one of the food items studied in connection to br...Soy foods associated with small reduction in risk of breast cancer
...cer risk. Some of these studies were based on the hypothesis that Asian women have reduced incidence of breast cancer, compared to American women, because they have traditionally eaten a diet rich in soy foods, such as tofu. In some studies, soy foods were just one of the food items studied in connection to br...Children who sleep less are three times more likely to be overweight
...one production is currently the researchers' prime hypothesis to explain the relationship between sleep and obesity. "Lack of sleep lowers the level of leptin, a hormone that stimulates metabolism and decreases hunger. In addition, short nights of sleep boost the concentration of ghrelin, a hormone that increas...Small study points to addictive effects of frequent tanning
...imes a year. The research was designed to test the hypothesis that exposure to ultraviolet (UV) light may produc... finding was unexpected and is consistent with the hypothesis that frequent tanning is may be driven in part by a mild dependence on opioids, most likely endorphi...Study shows rituximab effective in treating chronic graft-versus-host disease
...while B cells are derived from bone marrow.) This hypothesis gained traction when laboratory studies and small clinical trials showed that rituximab, which specifically targets B cells, could be effective against GVHD. The new study reinforces those findings with the largest group of chronic GVHD patients yet...Study to test drug's potential to preserve insulin production in newly diagnosed type 1 diabetics
...ells. Researchers designed this study based on the hypothesis that white blood cells called B cells serve as the "antigen presenting" cells, picking up antigens from the pancreas as though they were bits of infected cells, and presenting the pancreas antigens to the T cells. As a result, said Dr. Pescovitz, "Th...Doctors in training improve skills via virtual patient
...dents. "This new technology allowed us to test the hypothesis that electronic stethoscopes can be used as patient simulators to provide the necessary repetition to improve proficiency in cardiac auscultation," he explained. Because cardiac auscultation is a technical skill, Barrett believes that it is better le...Inflammatory biomarker helps identify progressive precancerous lesions in the lung
...hs. "These data are consistent with the prevailing hypothesis that squamous cell carcinoma arises from preinvasi...theory of cancer development," said Dr. Lam. "This hypothesis is supported by animal experiments mimicking human carcinogenesis." The authors believe that these r...Primary biliary cirrhosis more prevalent around toxic waste sites in NYC
...eople live. "Our observations further support the hypothesis that environmental toxin exposure is a risk factor for PBC," the authors conclude. They urge researchers in other locations to further investigate the association....Study ties 'new' cell-death mechanism to developmental and degenerative brain disorders
... neurodegeneration field has been dominated by the hypothesis of misfolded proteins and their aggregation, but t...ration do not necessarily supersede the prevailing hypothesis of defective proteins. In fact, the two may be linked. "It could be that the behavior of the nerve c...Use of statins shows improvement in erectile performance of some men
...ts show promise," adds Herrmann. "They support the hypothesis that erectile dysfunction may be one sign of a generalized vascular disorder characterized by endothelial dysfunction and that statin drugs may improve the endothelial dysfunction, even before altering the lipid profile. But the results are prelimina......says Gernsbacher. "An uncritical acceptance of the hypothesis that autistic individuals lack a theory of mind can seriously compromise how autistic individuals are treated in the workplace, the community and society in general." The other panelists will similarly address other stereotypes about autism. Judith ...