A potential new affordable diagnostic test for TB
A technique that identifies proteins* in the blood particular to tuberculosis (TB) could be used to develop a new diagnostic test for the disease, according to an Online/Article published today (Thursday September 14, 2006) by The Lancet. At present sputum smear microscopy is...New international guidelines for heart transplant candidates standardize patient care
... of patients while waiting for transplantation and identifies the need to provide the best available medical therapy prior to consideration for transplant. The task force outlines the necessary steps to follow prior to recommending a patient for transplantation, but also explores how to avoid transplantation, ...Stereotypes contribute to older men seeking, receiving depression care less frequently
...epression care documented in previous studies, and identifies reasons for these disparities. The findings are important in the arena of public health because of depression's association with suicide in older adults. Older men have higher rates of completed suicide: 31.8 per 100,000 in men age 65 and older, co...Nicotine receptors on kidneys may speed kidney damage
...e Council for High Blood Pressure Research -- also identifies nicotine as the component of cigarette smoke that damages the kidneys. "There are many substances in cigarette smoke and nicotine is one of the more investigated ones," said Edgar A. Jaimes, M.D., associate professor of medicine at the University o...Statement released on the assessment of coronary artery disease by computed tomography
...CLA Medical Center (LA BioMed), "Essentially, EBCT identifies calcium build-up or a plumbing problem in your heart. Our conclusions are very definitive that this is a test that's going to be useful in clinical practice." The EBCT offers cardiologists a non-invasive method for determining a patient's coronary ...American Thoracic Society publishes new statement on hepatotoxicity of antituberculosis therapy
...ng a patient's risk of developing liver damage and identifies directions for future research. "Hepatotoxicity has been a long-standing and often treatment-limiting concern for physicians caring for patients infected with active and latent TB," said Jussi J. Saukkonen, M.D., who chaired the statement writing ...Sports cheats beware -- new test detects previously undetectable drug
...print of the molecule a fingerprint that uniquely identifies it. "If the drug testing authorities adopt this new test it will close a gap in the current drug testing system, and mean that athletes will no longer be able to get away with this form of cheating," says lead author Mario Thevis, who works in the ......hat is characteristic of the original molecule and identifies it. The crucial new twist to Zenobi's method is the way the sample is inserted into the mass spectrometer. Usually, samples are first extracted and the resulting liquid is atomized with an electric field. Instead, Zenobi's team carries out a direct ...Children's Hospital Oakland Research Institute -- cancer study
...dren's Hospital Oakland Research Institute (CHORI) identifies a specific enzyme that can cause the death of cancer cells. Researchers studied the behavior of an enzyme called sphingosine phosphate lyase (SPL), which can regulate cell growth and death by lowering the levels of a natural, growth-promoting lipid c...New research identifies gene important for nicotine's effects on the brain
Nashville, TN, December 5, 2006 New research identifies an important gene that influences several aspects of nicotine-induced behaviors in the brain. The study, funded by National Institutes of Drug Abuse, was presented today at the American College of Neuropsychopharmacology's Annual Meeting. Investig...Aggressive stem cells might improve transplant outcome
...+ stem cells from the donated bone marrow actually identifies only a certain group of them, according to Raymond Barfield, M.D., Ph.D., assistant member of the Bone Marrow Transplantation division at St. Jude. The antibody usually used to capture CD34+ cells, called a class II antibody, recognizes a particular ...NIAID media availability: Examining genetic variability of malaria parasite offers insight
...taneously include one led by NIAID scientists that identifies new antigens--pieces of the pathogen that are recognized by the immune system. Some of these new antigens may be potential targets for new therapeutics or vaccines to help control malaria....New research explores limits of non-invasive coronary imaging tests
...ts of CAD. MSCT detects atherosclerosis, while MPI identifies ischemia." MSCT shows the anatomy of the coronary arteries, whereas MPI shows its function. MSCT is a rapid CT scan that provides a series of pictures to show how much plaque is in the coronary arteries. MPI with SPECT uses radionuclide imaging to ...Two central mysteries in genome inheritance solved at UCSD
... to be published in the December 15 issue of Cell, identifies a different type of connection between chromosomes and microtubule polymers, which operates to discriminate between correct and incorrect chromosome-spindle attachments. Each replicated chromosome is comprised of a pair of identical sister chromatid...New imaging technique identifies people-at-risk for Alzheimer's disease
...to report a real time "window into the brain" that identifies both of the major abnormal deposits of the disease in living people who may not develop Alzheimers for years to come. The researchers used positron emission tomography (PET) imaging with a small molecule invented at UCLA that binds to the abnormal p...Over 200 million children under age 5 failing to reach their potential in cognitive development
...es that exist to tackle poor child development and identifies those that are most effective. The authors conclude: "The most effective early child development programmes provide direct learning experiences to children and families, are targeted toward younger and disadvantaged children, are of longer duration...Annual study finds top hospitals have 28 percent lower mortality rate
... Clinical Excellence study, now in its fifth year, identifies hospitals in the top five percent nationally in terms of mortality and complication rates for 26 procedures and diagnoses, from bypass surgery to stroke. Hospitals achieving this level of care quality are designated Distinguished Hospitals for Clinic...Gene expression test reveals ER and HER-2 status of breast tumors
...d and validated a new genomic microarray test that identifies whether a tumor's growth is fueled by the female hormone estrogen and the role of a growth factor receptor known as HER-2 that makes a tumor vulnerable to a specific drug. The status of these factors is now determined by pathology tests. "This is o...PET imaging identifies aggressive kidney cancers that require surgery
...phy (PET) using a radiolabeled antibody accurately identifies whether a patient has clear cell renal carcinoma the most common and aggressive type of renal tumor and arms the urologist with crucial information that will help determine whether surgery is needed. Conducted by researchers at Memorial Sloan-Ket...National Institute of Dental and Craniofacial Research activities
...dmap" for medical research in the 21st century. It identifies the most compelling opportunities in three main areas: new pathways to discovery, research teams of the future, and re-engineering the clinical research enterprise. The NIH recently announced the launch of a national consortium that will transform ho...