Sucampo submits new drug application for lubiprostone
... mechanism of action, for the treatment of chronic idiopathic constipation (CIC) and associated symptoms in adults. Administered orally, the agent has been shown to work locally in the GI tract by activating specific chloride channels (a protein that carries chloride) on cells lining the small intestine, incr...Study concludes primary IGF-1 deficiency is a frequent cause of short stature
...ture among patients currently classified as having idiopathic short stature, or short stature with no known caus...be recognized as a diagnostic subset separate from idiopathic short stature. "As knowledge of the molecular basis of growth improves, new categories for classifyi...Several factors can increase risk for recurrent blood clot
...women. Patients whose initial thrombotic event was idiopathic (unknown cause) had nearly two times the risk of a...cal factors (male sex, oral contraceptive use, and idiopathic first thrombotic event) rather than laboratory abnormalities," the authors conclude....Study shows new method of growth hormone dosing improves height
...short stature due to growth hormone deficiency and idiopathic short stature. The groundbreaking study, presented...owth-hormone deficiency patients and patients with idiopathic short stature. "We feel confident that IGF-based growth hormone dosing could become a novel paradig...VCU researcher leads international team in developing guidelines for treating hydrocephalus
...tients." The new guidelines deal exclusively with idiopathic NPH, the form of NPH that develops from no known cause. Doctors are advised of which tests to use to make a diagnosis and how to determine if treatment with a shunt a flexible tube and valve will help reverse or improve the condition. NPH is treate...Study provides guidelines for treatment of juvenile idiopathic arthritis
...ime with specific guidelines for treating juvenile idiopathic arthritis (JIA), previously known as juvenile rheu...sity of Toronto. "The most common form of juvenile idiopathic arthritis affects approximately one in a 1,000 Canadian children and if left untreated can result in...Brain abnormality found in Alzheimer's disease related to gait impairment in older persons
...with and without dementia but excluded people with idiopathic Parkinson's disease. Though less than half of the subjects had dementia, the study found nearly 78 percent of test subjects had neurofibrillary tangles in the substantia nigra. Annual neurological examinations included an assessment of parkinsonian ...JRRD special issue on hearing and hearing loss
...ment techniques , pg 1 Noise-induced hearing loss, idiopathic sudden sensorineural hearing loss, otosclerosis, and Meniere's disease are discussed in this article. Sensorineural hearing loss characterizes each, but additional aspects vary with each of the conditions. This article describes the conditions, discu...Curtin medal recognises epilepsy researcher
...e known genes in which mutation is associated with idiopathic epilepsies. These discoveries have revolutionised basic scientific research into epilepsy. The John Curtin School of Medical Research (JCSMR) awards the Curtin Medal annually to a person who has made an outstanding contribution to medical science and...Hormone can predict pulmonary hypertension and potential death or survival
...eased workload in the right heart originating from idiopathic pulmonary arterial hypertension," Dr. Behr said. During the 10 months following the study, 31 participants (18 percent) died of cardiopulmonary causes. "Patients who died during the follow-up period more frequently had elevated BNP levels and promine...AMITIZA (lubiprostone) launches in the United States
...oss the United States for the treatment of chronic idiopathic constipation in adults. AMITIZA (pronounced ahm-e-... activator approved for therapeutic use in chronic idiopathic constipation, a condition that affects both men and women and affects patients over the age of 65 mo...Childhood arthritis raises risk of broken bones
...ractures in childhood arthritis patients. Juvenile idiopathic arthritis (JIA), also called juvenile rheumatoid arthritis, is the most common pediatric rheumatic disease, affecting approximately one in 1,000 U.S. children. It was already known that low bone mass occurs in patients with JIA, because of risk facto...Study investigates Nexium benefits patients with Zollinger-Ellison syndrome
...els in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion (IGH). Results of the...l acid output (AO) control in patients with ZES or idiopathic (of unknown cause) gastric acid hypersecretion (IGH). Patients (n=21) being treated with a PPI for ...AMITIZA(TM) (lubiprostone) shown effective and well-tolerated in people older than age 65
...ide channel activator for the treatment of chronic idiopathic constipation, was effective and well-tolerated in treating the symptoms of chronic idiopathic constipation in the elderly adult population according to findings presented during a poster session...New study demonstrates that AMITIZA (lubiprostone) may help improve symptoms
...ontrolled clinical trials in patients with chronic idiopathic constipation. AMITIZA was approved for use for chronic idiopathic constipation in adults on January 31, 2006. This is the first time AMITIZA has been tested exclusive...Abnormal glucose metabolism may contribute to chronic nerve disorder
...rmine the cause, the condition is known as chronic idiopathic axonal polyneuropathy; a cause is eventually found...cutive patients (60 women and 40 men) with chronic idiopathic axonal polyneuropathy who were evaluated between January 2003 and January 2005. Patients underwent ...REM sleep behavior disorder found to be precursor of brain-degenerating diseases later in life
... "Hopefully, early identification of patients with idiopathic RBD will lead to close monitoring and early treatment of any developing neurological disorders."...Very early signs of atherosclerosis and heart failure seen together on MRI
...veral patients who are otherwise labeled as having idiopathic cardiomyopathy. Decreased coronary flow reserve in the face of increased demand such as occurs during exercise or mental stress may lead to reduced heart function during stress and then eventually at rest. It would be interesting to find out whether ...Tocilizumab study offers new hope for children with arthritis
...ocilizumab amongst children with systemic juvenile idiopathic arthritis (sJIA), who do not tolerate or have an i...ope.1 "Systemic JIA is a specific type of juvenile idiopathic arthritis and it is one of the most severe types as it affects the whole body and most of the joints...Identification of role for proteins in children's muscle disease could open up new treatment options
...fic response has earlier been observed in juvenile idiopathic arthritis, but to date, little is known about the role of HSP60 in inflammatory myositis. Inflammatory myositis (IM) is the name given to a group of diseases that cause inflammation in the muscles of the body, which is mediated by the immune system o...