Chemotherapy may enhance the effectiveness of brain tumor vaccines
....C. -- Chemotherapy temporarily hinders the body's immune response, creating a concern that it may interfere... to kill cancer cells, chemotherapy also wipes out immune cells," said John Sampson, M.D., Ph.D., a neurosurgeon at Duke and lead investigator on the study. "...Protein may be linked to melanoma recurrence
...e to treatment with interferon. Autoimmunity is an immune response against the bodys own tissues. With further study, we hope to learn more about the role of S-100 in melanoma survival, said Joseph Stuckert, medical student at the University of Pittsburgh School of Medicine who is presenting the study a...OHSU Cancer Institute shows findings of immunotherapy vaccine in prostate cancer patients
...e treatment arm to which they were randomized. An immune monitoring protocol performed in a subset of patients demonstrated that the immune response elicited by sipuleucel-T was long-lived and still strong just prior to the booster infusion...Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
...tance a protein called adiponectin helps prevent immune system white blood cells from binding to the inside of blood vessel walls. Harnessing adiponectin's properties, the scientists suggest, may someday help protect against the blood vessel damage so prevalent in patients with obesity and diabetes. Re...Mouse model points to possible new strategy for treating rare muscle disease, kidney disorders
...ength among HIBM patients who received intravenous immune globulin G an effect that researchers suspect was...hrough the provision of sialic acid present in the immune globulin. NHGRI researchers expect the clinical trial of ManNAc for HIBM to begin in late summer ...When HIV and liver disease co-exist
...g those with HIV. Conference attendees discussed immune responses to hepatic disease in patients with HIV as well as how the viruses interact to result in liver injury. They also considered how treatment options, including antiretroviral agents, might affect the liver. In treating HIV/HCV co-infected...Study tests oral insulin to prevent type 1 diabetes
...aid. We hope that learning about the underlying immune events that set the stage for diabetes will help u...gestive tract induces tolerance, a quieting of the immune system. First- and second-degree relatives of people with type 1 diabetes who may be at risk are i...OHSU Cancer Institute researcher identifies protein marker for prostate cancer survival
...nse and the inflammatory cytokines released by the immune reaction may in fact fuel cancer progression. To the extent that our hypothesis proves true, C-reactive protein may be reflecting the overall intensity of the inflammation," Beer said. The finding that higher CRP is associated with shorter surviva...Brain inflammation may be friend, not foe, for Alzheimer's patients
...trategies against Alzheimers by engaging the bodys immune system. The team expected to see the telltale cl...lvement of brain cells called microglia, the major immune cell that rushes to injury sites and helps repair and clean up wounds in the brain. The work is th...International studies show high efficacy for HPV vaccine
...t argues, "young women, young girls make very good immune responses to this vaccine, so that will enhance their protection. Widespread immunization with the HPV vaccine along with continued screening will help decrease the burden of cervical cancer and other HPV-related diseases," he says....Human antibodies protect mice from avian flu
...es of Health, report using antibodies derived from immune cells from recent human survivors of H5N1 avian influenza to successfully treat H5N1-infected mice as well as protect them from an otherwise lethal dose of the virus. "The possibility of an influenza pandemic, whether sparked by H5N1 or another inf...HIV and malaria combine to adversely affect pregnant women and their infants
...ry of Science) pinpoints how the virus targets the immune response in pregnant women. "PAM can be a deadly condition that leaves mothers and their children particularly vulnerable," says Professor Kevin Kain, an infectious disease specialist and lead author of the study. "We set out to understand how women ...Syphilis screening, lithium fights neurodegeneration, monoclonal antibodies against avian flu
...chers isolated and immortalized antibody-producing immune cells from the patients blood and purified the antibody made by individual cells. These monoclonal antibodies were then tested for their ability to neutralize H5N1 and other flu viruses in laboratory assays. The researchers identified several antibod...ECP may be effective in treating Crohn's disease
...enter. ECP is believed to bolster tolerance in the immune system, which may be important in immune-mediated ...currently treated with medicines that suppress the immune system. Unlike ECP, those medications can have many serious side effects. The 28 patient trial ...Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
...iciency virus (FIV), a lentivirus that attacks the immune system of cats. It resembles HIV in humans, but is incapable of causing human infection. Despite the strong results, however, the team will seek to deliver the same gene therapy with a different vector in the next phase of experiments. Kyrkanides ...UCLA pediatrician honored with prestigious achievement award
...he research and treatment of primary and secondary immune deficiency disorders in infants and children. ... research has included the description of neonatal immune defects, bone marrow and cord-blood transplants in cellular immunodeficiencies, and the uses of immu...Hepatitis C negatively impacts HIV
...hat HCV infection may adversely impact HIV-related immune reconstitution." "If this is true, additional improvement in HIV outcomes may be achieved by effective treatment of HCV infection in patients who are adherent to ART."...Soldiers acquired drug-resistant infections in field hospitals
...eople. However, those with open wounds or weakened immune systems are at greater risk of ABC infection. An ABC infection can cause or contribute to death, especially if the patient is immunosuppressed. Historically, ABC infections were treated with a wide variety of drugs. Unfortunately, in recent years, ...Scavenger cells may have role blocking obesity, Stanford study shows
...-- Macrophages - the scavenger cells of the body's immune system - are known as troublemakers for the role t...st cellular debris and pathogens, triggering other immune cells to aid in the response to a pathogen. But in recent years, macrophages found in fat tissue of ...HIV's effect on white blood cells questioned by new research
...hich recognise infection and co-ordinate the bodys immune defences. They are attacked by HIV, and their numbers gradually decline in HIV positive patients. It has long been a major puzzle why this process of depletion is so slow, often taking 10 years or more. One popular theory has been the runaway hypot...