Tag: "immunity" at medical news
Asthma patients' immune systems respond differently with allergies
...ocytes produce cytokines that mediate and regulate immunity
and inflammation to an immune stimulus. Because people with asthma and allergy share this common etiological pathway, they show different expressions of their disease with a wide variety of therapeutic responses. That's why Dr. Leal-Berumen's labora...
West Africa: meningitis epidemics driven by the wind
...ontribute to epidemic onset, in particular loss of immunity
among communities in the face of the bacterial agent, owing to the renewal of generations and the increase in the number of individuals who have never been in contact with it, and also because of climatic conditions. Sahelo-Sudanian Africa is under a...
Scientists discover way to control allergic reactions
... hugely important step in our understanding of how immunity
and inflammation play a role in allergic reactions. Although we have known about the role of these regulatory immune cells for a number of years, this is the first time we have found a way to manipulate them to help control allergic reactions." There...
Combination vaccine produces lower immune response than vaccines administered separately
...f vaccines infants receive appears to provide less immunity
than the vaccines administered individually, according to a study in the April 13 issue of JAMA. The development of immunogenic vaccines against major diseases of childhood has dramatically decreased the rates of invasive disease, according to backgr...
NIAID begins clinical trial of West Nile virus vaccine
...ccine's exploitation of both cellular and antibody immunity
offers a potentially potent defense against West Nile virus," says Barney Graham, M.D., Ph.D., chief of the VRC's Clinical Trials Core Laboratory. Adds Dr. Graham, "In our experience in clinical trials, DNA vaccines generally cause few side effects, ...
Discovery of a 'molecular switch' could lead to new ways of treating infection, including MRSA
...m investigated the role of IKK in inflammation and immunity
by comparing the response of mice with a defective IKK enzyme, compared to normal mice, when exposed to the pathogen Streptococcus. In the mice without IKK, they found significantly increased killing of bacteria in sepsis and pneumonia, but found tha...
A candidate biomarker to improve treatment of lupus patients
...t on the role of interferon, a protein critical to immunity
released into the bloodstream, in the progression of SLE. Supported by the Alliance for Lupus Research, the Lupus Research Institute, the Mary Kirkland Center for Lupus Research, and the NIH, the study was conducted by a team of researchers with the ...
Enhancing innate immunity improves Crohn's disease symptoms
...t a new study demonstrates that stimulating innate immunity
also is effective at improving symptoms in many pa... of Crohn's disease by enhancing the body's innate immunity
since the mid-1990s. "The idea of priming the immune system in patients with Crohn's disease sound...
Experimental shingles vaccine proves effective in nationwide study
...d, where the virus persists in a dormant state. As immunity
weakens with advancing age, the virus can reactivate, multiply in and damage sensory nerve cells to cause pain. It then migrates to the skin, causing the blistering rash of shingles. Generally, shingles first manifests as pain, itching or tingling ...
Booster vaccine for adolescents and adults that includes protection against pertussis shows promise
...yet on the market appears to provide a booster for immunity
against tetanus, diphtheria, and pertussis for ado...rtussis disease." The authors continue, "Waning immunity
to pertussis has been demonstrated in adolescents and adults, indicating increased susceptibility to...
JAMA study finds whooping cough vaccine effective, safe for teens and adults
...d that these acellular vaccines created comparable immunity
with whole cell vaccines, but with the potential f...at this Tdap vaccine provided comparable levels of immunity
to that of the Td booster, and to the pertussis component of DTaP (licensed pediatric) vaccine. The ...
Chest x-rays not effective in determining when TB acquired
... recent infection or are manifestations of altered immunity
in the reactivation of latent infection. The stud...of pulmonary tuberculosis in HIV is due to altered immunity
rather than recent acquisition of infection and progression to active disease." Although a clustered...
Mayo collaboration: Discovery blocks breast cancer growth, stimulates immunity
...py. Depleting T-regulatory cells may boost natural immunity
against breast cancer." Significance of the Research The Mayo Clinic and University of Washington collaborative study is the first to show these two new important aspects of breast cancer: T-regulatory cells play a disease-promoting role in...
Hepatitis A in US drops substantially after implementation of vaccination program
... as vaccinated children grow to adulthood, because immunity
to hepatitis A virus by vaccination is long-lasting. Health officials in Israel decided to introduce universal vaccination of toddlers against hepatitis A because of epidemiologic evidence and a cost-benefit analysis of the program. The program start...
Tulane pioneers novel ovarian cancer treatment
...will test the hypothesis that Ontak improves tumor immunity
by killing regulatory T cells (Tregs) in patients ... showed that human tumor Treg cells suppress tumor immunity
and contribute to growth of tumors. Thus, killing Treg cells may help treat cancer, Curiel says. The...
Malpractice litigation wrongly blamed for inconsistent health care
...ctice as much as they say they do, the prospect of immunity
should be an immediate incentive for the implementation of these standards." Hyman is a professor in the Illinois College of Law, College of Medicine and Institute of Government and Public Affairs. Silver is co-director of the Center on Lawyers, Civi...
Laparoscopic surgery associated with reduced inflammatory response
...at our observation of better preserved nonspecific immunity
[natural killer cells] in patients after laparoscopic colorectal surgery has beneficial effects on perioperative infectious complication rates--which is true for patients with benign as well as malignant colorectal disease."...
Not enough is known about treating malaria in pregnancy, researchers say
...s in the area are so high that women may have some immunity
to the disease by the time they become pregnant, preventing serious illness in some cases. In Africa, therefore, drug trials focus on prevention rather than treatment of the disease, Orton and colleagues say. In Asia, on the other hand, transmission...
A new understanding of how immune system targets disease
... them. Pathogens use the same tricks to escape the immunity
provided by vaccines. In an effort to deny diseases the ability to hide, researchers have for years been asking a key question: Why do our bodies select certain, small pieces (epitopes) of each disease-causing molecule to trigger an immune response, ...
Cancer vaccine under development using synthetic protein
...eviously have used synthetic peptides to stimulate immunity
to viruses and cancers where naturally-occurring peptides were failing. However, many of these peptides have been unstable and degraded in the blood and peripheral tissues. Associate Professor Mibel Aguilar and Dr Patrick Perlmutter from Monash and...
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