Damon Runyon renews its $2.25 million investment to support young clinical cancer investigators
.... Specifically, she is designing a tumor-specific immunotherapy with minimal side effects that will target the leukemia stem cells and ultimately lead to a non-toxic therapy to cure CML....GSK announces launch of largest ever Phase III trial in lung cancer treatment
...lls in a highly specific manner. This novel cancer immunotherapy is developed using tumor specific antigens, delivered as highly purified recombinant proteins, and GSKs own proprietary Adjuvant Systems, which are specifically designed to enhance ASCIs anti-tumor activity Phase II NSCLC Clinical Trial Results: ...Protein may be linked to melanoma recurrence
...were treated with high-dose interferon, a standard immunotherapy treatment for melanoma, an average of eight years prior. The disease recurred in 64 of the patients within an average of 30 months. When the researchers examined levels of S-100 in the serum samples, they found that the higher the level of the protei...OHSU Cancer Institute shows findings of immunotherapy vaccine in prostate cancer patients
...plore the biologic and clinical activity of cancer immunotherapy sipuleucel-T, or Provenge, in patients with early ...reaches 3.0 ng/ml. Although there was a trend, the immunotherapy did not significantly delay cancer progression by this measure. However, investigators found the rat...Syphilis screening, lithium fights neurodegeneration, monoclonal antibodies against avian flu
...erent clade. These results indicate that passive immunotherapy with human monoclonal antibodies could help to com...1 if (or when) it starts a human pandemic. Passive immunotherapy is already used to prevent infections with several viruses. In addition, a crude form of the approac...'Erectile dysfunction' drugs heighten natural anti-cancer activity
...ld be used in addition to standard chemotherapy or immunotherapy treatments." The investigators are planning human studies to begin in the next year....Innovative movies show real-time immune-cell activity within tumors
...procedure, referred to as adoptive transfer, is an immunotherapy strategy against cancer being tested in a number of human clinical trials. In some of those trials, a patient's own T cells are removed, tested for their ability to recognize the patient's cancer cells, activated and expanded greatly in numbers in th...Study shows six-injection allergy vaccine tames hay fever for at least 2 years
...rs. The researchers believe that the six-injection immunotherapy regimen with a novel DNA-based drug known as 'AIC'...urther treatment of these individuals. Standard immunotherapy is a long-established treatment with proven clinical benefits for a number of allergic conditions, i...New allergy vaccine provides long-lasting hay fever relief after just 6 weeks of shots
...nes, and providing a safer, faster replacement for immunotherapy regimens, which are costly and take years to work, the researchers say. The Hopkins study, conducted during two fall ragweed ("hay fever" ) seasons in Baltimore, Md., enrolled 25 volunteers, ages 23 to 60, with a demonstrated history of ragweed al...Experimental ragweed therapy offers allergy sufferers longer relief with fewer shots
...Director Anthony S. Fauci, M.D. "A short course of immunotherapy that reduces allergic symptoms over an extended pe...led allergen immunotherapy. Although this standard immunotherapy is often effective, it has two major drawbacks. First, it can cause systemic allergic reactions, suc...T cells activated to fight HIV basis for dendritic cell therapeutic vaccine
...activation by dendritic cells provides a basis for immunotherapy trials of persons with HIV infection," said Dr. Huang. The trial should be enrolling patients within the year, pending approval by the U.S. Food and Drug Administration. The researchers have already completed a similar trial in 18 patients that pro...New hope in cancer vaccines emerges as novel therapies are developed and tested
...iting to us because people have been trying to use immunotherapy against gliomas for a long time."...Study shows prostate cancer vaccine linked to longer survival
...o patients and would represent the first time that immunotherapy has provided a survival advantage in prostate canc...y its product name Provenge, is an investigational immunotherapy vaccine designed to stimulate T-cell immunity to prostatic acid phosphatase, an antigen found in abo...Buckyballs boost antibody's chemotherapy payload
...l is exciting, but the real advantage of fullerene immunotherapy over other targeted therapeutic agents is likely to be the buckyball's potential to carry multiple drug payloads, such as Taxol plus other chemotherapeutic drugs," said Rice's Lon Wilson, professor of chemistry. "Cancer cells can become drug resistan...M. D. Anderson: Setting the benchmark in brain tumor treatment
...iting to us because people have been trying to use immunotherapy against gliomas for a long time," she says. "We need to find ways so that these therapies can work together synergistically." She adds that the vaccine could potentially be used for breast and lung cancers, and a trial has been opened at the Universi...Study finds novel vaccine curbs brain tumor growth, increases survival
...iting to us because people have been trying to use immunotherapy against gliomas for a long time." Heimberger and a team of researchers designed the vaccine to alert the brain's immune system to the presence of just one type of protein that studs the outside of a glioma tumor. This protein, epidermal growth factor...Protein sorting in pigment cells sheds light on melanoma, Alzheimer's disease
...ell. "Exosomes are a very hot topic now in cancer immunotherapy because dendritic cells are good at taking them up, processing the associated antigens, and presenting them to helper T cells, which then rally the immune system to fight the tumor." Marks says that understanding how and why the sorting process is re...Jefferson Pancreatic Cancer Conference Feb. 24 highlights treatments, trials, vaccine research
...ry, animal models, clinical trials, treatments and immunotherapy at this year's Scientific and Clinical Update on Pancreatic Cancer. Jefferson is hosting the conference at its Bluemle Life Sciences Building, 233 S. 10th Street. (The conclave begins at 8:20AM in Room 101.) Among the guest speakers is Elizabeth Jaff...JCI table of contents: December 1, 2005
...ing the number of patients eligible for mHAg-based immunotherapy following hematopoietic stem cell transplantation. TITLE: A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia AUTHOR CONTACT: Harry Dolstra Radboud University......Hodgkin's lymphoma are being treated with BiovaxID immunotherapy following PACE [Prednisone, Doxorubicin, Cyclophosphamide, and Etoposide (ProMACE without methotrexate)] chemotherapy. At the meeting of the American Society for Hematology, Biovest will provide an update on patients who were treated with BiovaxID ...