Tag: "induced" at medical news

Statin simvastatin linked to protection against endothelial dysfunction in diabetic rats

...rs and appears early in diabetes. The researchers induced diabetes in rats, then treated half of the diabeti...ndicate that simvastatin protects against diabetes induced dysfunction," and Dr. Caldwell says, "The usefulness of statins in the treatment of diabetic patient...

Angiogenesis factor may help tumors prepare the way for spread to lymph nodes

...search at the MGH and elsewhere found that it also induced proliferation of lymphatic tissue and vessels in l...e elevated levels of VEGF-A. The researchers then induced the development of benign and malignant skin tumors in both the transgenic mice and normal mice in o...

Hemodialysis causes antioxidant loss leading to long-term complications

...is patients are in a state of chronic inflammation induced by the dialysis process which further enhances oxidative stress. This state is strongly associated with long-term complications such as cardiovascular disease, malnutrition, poor outcome and low survival. "It is important to prevent reactive oxyge...

Rats with migraines provide Jefferson scientists insights to improved drug strategy

...n, he can monitor the effects of medication on the induced headache. He found that pretreating with DHE, and treating with DHE at the beginning of the induced headache prevents the headache from progressing to the debilitating sensitization state. "Physicia...

Spice it up or just veg out, either way you may be helping to defend against cancer

...on resulting in the release of cytochrome c, which induced apoptosis, or programmed cell death, in the cancerous cells without affecting normal pancreatic cells. "Our results demonstrate that capsaicin is a potent anticancer agent, induces apoptosis in cancer cells and produces no significant damage to nor...

Study finds moderate hypothermia a safe treatment for traumatic brain injury in kids

...delson, MD, and fellow researchers determined that induced moderate hypothermia initiated after severe traumatic brain injury (TBI) is a safe therapeutic intervention for children. TBI initiates several metabolic processes that can exacerbate the injury. Adult research has produced evidence that hypothermia ...

Excess oxygen worsens lung inflammation in mice

... an animal model, Dr. Sitkovsky and his colleagues induced lung inflammation in three groups of mice. The first group of 15 mice did not receive any supplemental oxygen. While they sustained moderate lung damage, only two died. Another group of 15 mice with acute lung inflammation were treated with either 10...

FDA approves Boostrix a new US vaccine for adolescents against pertussis

... immunogenicity. In addition, the use of Boostrix induced anti-pertussis antibody levels which were non inferior to those observed in infants following a primary immunization series with a DTaP vaccine (Infanrix?) [Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed] in whom efficacy aga...

UCI eye doctors invent laser-assisted cornea-transplant surgery

...r the mechanical strength of the incisions and for induced distortion. They found that the initial strength of the laser incision, even before any healing, measured almost seven times higher than that of the incision from the usual transplant technique performed by hand. The laser used to cut the cornea is...

American Thoracic Society Journal news tips for May 2005 (second issue)

...nce of eosinophils (a type of white blood cell) in induced sputum. According to the authors, asthma is charac...ccessful in all children who had no eosinophils in induced sputum before the attempted reduction. They said that the percentage of sputum eosinophils and an ex...

Breast cancer chemotherapy regimen associated with life-threatening complications

...doxorubicin-cyclophosphamide in our trial may have induced severe immunosuppression and contributed to the high rate of toxic death, which was 3 times as much as that observed in [another trial], in which 3 of 7 deaths were attributable to sequential docetaxel immunosuppression among 1,584 patients (0.19 per...

Other highlights in the May 18 JNCI

...e that regulates cytochrome c release. Triacsin c induced apoptosome-mediated cell death in tumor cells and suppressed the growth of lung tumors in a mouse model. The authors conclude that acyl-CoA synthetase inhibition may be a novel strategy to induce p53-defective tumor cell death. Contact: Tetsuo Mashi...

Timing of introduction of gluten into infant's diet associated with appearance of celiac disease

...ed by chronic inflammation in the small intestine, induced by gluten (a protein substance) present in wheat, rye, or barley, according to background information in the article. The classic form of celiac disease typically presents in early childhood with abdominal pain and diarrhea, malabsorption, and nutrie...

Study shows grapefruit extract can heal stomach ulcers

...ng gastric ulcers. For the study, investigators induced gastric ulcers in rats and applied graded doses of GSE (2-20 mg/kg) to measure levels of gastric secretion, one the major causes of gastric ulcers. The team tested ulcer healing by using a combination of acetic acid (an acid compound used to induce ...

Common incontinence drug could have an additional topical effect on the bladder itself

...ed into the bladders of animal models. Researchers induced bladder overactivity using carbachol. The trospium bladder did not react to the carbachol, indicating that the trospium had a topical effect on controlling the muscle contractions. In the control, tolterodine- and oxybutynin-treated bladders, the len...

Laughter-induced asthma: It's no joke

...h laughter-induced asthma compared with asthma not induced by laughter (61% of people with LIA vs. 35% of asthma patients without LIA). Dr. Garay was struck by how common laughter-induced asthma is. "It's as common as some of the most well-known asthma triggers, such as grasses, trees, pollen, fumes and odor...

Researchers study natural products that may prevent certain cancers

... studies CAPE has protected mice against radiation induced inflammation and skin damage and rats against certain forms of heart muscle damage following chemotherapy treatment. Curcumin is the yellow pigment of the spice turmeric. Based on studies that showed dramatically reduced rates of colon cancer in popu...

Bad metabolism in blood vessels linked to high blood pressure and atherosclerosis

.... "It is possible that the decreased energy stores induced by the uncoupling protein caused cells to move more oxygen through the system. But the increased flux of oxygen through the blood vessel wall caused oxidative damage, high blood pressure and atherosclerosis." That may be what happens as people age, a...

UNC launches study of liver injury caused by drugs

... insight into medical problems beyond liver injury induced by drugs, he added. "Drug-induced liver injury is an ideal model to study how genes and environment interact to produce disease in some but not all people. We hope the factors identified by DILIN research will provide clues to susceptibility to the ...

Practice of defensive medicine widespread among physicians in specialties at high risk of lawsuits

...is a deviation from sound medical practice that is induced primarily by a threat of malpractice suits, according to background information in the article. Defensive medicine has been reported widely in the United States and abroad. However, its prevalence and characteristics remain controversial. According t...

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(Date:11/18/2014)... 2014 The Parenteral Drug Association (PDA) today confirmed ... speak and at least seven more will participate in the ... Shoreham Hotel in Washington D.C. , Dec. ... significant support from the regulatory agencies in the ... in our effort to help advance the use of metrics ...
(Date:11/10/2014)... on U.S. store shelves in early 2010, and people ... small packets can be tossed into a washing machine ... powder. The convenience, though, has come with risks for ... Nationwide Children,s Hospital found that from 2012 through 2013, ... younger than 6 years of age swallowing, inhaling, or ...
(Date:11/6/2014)... yet progress in preventing and treating migratory cancer ... challenging to design drugs that work against metastasis," ... at Harvard Medical School. , "Unfortunately, many ... , Gujral and colleagues have now identified a ... how metastasis begins. Their findings may also inform ...
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