New clinical team approach reduced cardiovascular risk
...lesterol abnormalities, hypertension, clotting, or inflammatory protein factors in their blood. This leaves them extremely vulnerable to cardiovascular diseases caused by plaque deposits. These include coronary and/or peripheral artery disease and strokes. The team reviewed charts of over 480 patients treated in ...The promise of a B-cell biologic therapy for rheumatoid arthritis
...treatment of rheumatoid arthritis (RA), a chronic, inflammatory autoimmune disease. Still, the frequency of remis...omplaint. Confirming the role of B cells in the inflammatory processes behind RA, this study demonstrates the effectiveness and safety of a unique biologic thera...Minimally invasive approach can take the pain out of herniated disks
...ubstance. "The goal is to reduce the pressure and inflammatory factors in the disk with a minimal amount of remov...hey suspect it's related to a change in the mix of inflammatory factors over time that results in more healing factors and fewer destructive ones. The approach is s...UCI researchers to study health effects of exercise in children
...dy will examine the molecular mechanisms that link inflammatory and growth-factor responses to exercise, and anoth...rtise. In addition, a pediatric growth, stress and inflammatory mediator core laboratory will ensure optimal and efficient use of analytic resources. The laboratory...FDG-PET accurate for evaluating lung tumor destruction from radiofrequency ablation
...ssess how much of the ablated area is caused by an inflammatory reaction to the procedure. By using PET, the tumor cells that are still alive light up and the radiologist can better assess how much residual active tumor is left," said Jennifer Daly, MD, of the Newton-Wellesley Hospital in Newton, MA, and lead au...JCI table of contents: May 1, 2006
...imal variability that is seen in the IL-4-mediated inflammatory response in humans and animal models of human dise...cle.php?id=28506 IMMUNOLOGY IL-23 and IL-17: The inflammatory axis of evil Inflammation is a hallmark symptom of many diseases, and can cause significant damage ...H5N1 threat puts human flu back in spotlight
...o H5N1 can run amok, with immune cells spewing out inflammatory chemicals called cytokines in a "cytokine storm" that causes airways to become inflamed and the alveoli to fill with fluid. The result can be rapid death. According to the investigators, this finding at least partially explains why so many young, oth...Halting histamine action means hallelujah for hay fever sufferers
...viously unknown role for H1R in the development of inflammatory airway responses. They found that these mice do in...ed to the lung or able to cause the characteristic inflammatory allergic response in these mice. This advancement of our understanding of the roles of histamine in ...JCI table of contents: May 4, 2006
...viously unknown role for H1R in the development of inflammatory airway responses. They found that these mice do in...ed to the lung or able to cause the characteristic inflammatory allergic response in these mice. This advancement of our understanding of the roles of histamine in ...Childhood arthritis raises risk of broken bones
...earch on bone and muscle strength in JIA and other inflammatory diseases....How bad is malaria anemia? It may depend on your genes
...unts as part of the body's normal response to such inflammatory conditions as rheumatoid arthritis or some cancers...ter also have been linked to the severity of other inflammatory diseases. The researchers continue to collaborate in an effort to develop drugs that might block MIF...Surgeons need to be more aware of techniques to prevent postoperative pain
...ve injury include careful dissection, reduction of inflammatory responses, and use of minimally invasive surgical techniques state the authors. Professor Kehlet concludes: "Postsurgical persistent pain is a major, largely unrecognised clinical problem, which is distressing and reduces the quality of life of pati...JCI table of contents, May 11, 2006
...sity and insulin resistance by the induction of an inflammatory response (macrophage infiltration) in fatty tissue. The authors suggest that blocking the interaction of MCP-1 and its receptor, known as CCR2, might provide the basis for development of new therapies for this syndrome. TITLE: MCP-1 contributes to m...More than just genetics: Lifestyle choices impact GI health
...nmental factors that may affect the development of inflammatory bowel disease (IBD), specifically ulcerative colitis (UC) and Crohn's disease. They found several factors that exerted possible protective effects against the diseases, including breast-feeding, number of home occupants early in life, and the presen...Biologic therapies lead evolution of Crohn's treatments
...HARM Trial [Abstract 686d] Because of the similar inflammatory proteins that are increased in patients with arthritis and Crohn's disease (CD), many research teams are performing trials of arthritis medicines to evaluate their benefit for GI diseases. This study reviews the efficacy and safety of maintenance th...Air pollution increases death risk in people with certain diseases
...failure, chronic obstructive pulmonary disease and inflammatory diseases such as rheumatoid arthritis are at incre...with congestive heart failure 22% for people with inflammatory disease such as rheumatoid arthritis or lupus "The study significantly strengthens evidence that br...New compounds fight chronic symptoms of bowel disorders
...he injured tissues. In previous animal studies of inflammatory bowel disease, teduglutide has reduced inflamation and healed injured intestinal tissue. In the exploratory study, 100 participants with active Crohn's disease were randomized and treated with one of three doses of teduglutide or placebo for eight w...Immune signals of variations of a single gene linked to more severe Crohn's disease
...nt Sinai School of Medicine. Crohn's Disease is an inflammatory bowel disease that causes inflammation or ulceration of the gastrointestinal tract and can sometimes run in families. While the cause is unknown, many professionals believe that the body's immune system may overreact to normal intestinal bacteria or ...New analysis showed UC patients in clinical remission had higher rates of employment
...oved for UC and Crohn's disease (CD), both chronic inflammatory bowel diseases (IBDs). The analysis presented today compares all patients in all treatment arms who achieved remission to all patients in all treatment arms who did not achieve remission. This analysis does not compare REMICADE to controls in term...Health benefits of Chlamydia screening programmes 'might have been overestimated'
...rate calculated for a hospital diagnosis of pelvic inflammatory disease (infection of the fallopian tubes), ectopi... earlier studies had suggested. The rate of pelvic inflammatory disease or PID was just under 4% by the age of 35 across the entire group. In those who had tested p...