Air pollution found to pose greater danger to health than earlier thought
...roke. They believe particulate matter may promote inflammatory processes, including atherosclerosis, in key tissues. "We have convincing evidence that those causes of death that we might expect from inflammation, ischemic heart disease and lung disorders, are elevated in areas of higher pollution levels," he say...Johns Hopkins researchers discover key protein linked to transverse myelitis and multiple sclerosis
...evoted to TM in the world. Researchers analyzed 42 inflammatory proteins in the cerebrospinal fluid of both TM and healthy patients. They found that IL-6 was consistently elevated in TM patients' spinal fluid. Further, the level of IL-6 directly correlated with the severity of paralysis. Using cell culture and an...Air pollution linked to heart attack
...ient ozone on the procoagulant status and systemic inflammatory response by Hermans et al and Exposure to diesel exhaust nanoparticles does not induce blood hypercoagulability in an at-risk population by Blomberg et al.) which challenge these results. They are also available to media upon request. Anyone sensiti...Potential new treatment for insulin-dependent diabetes
...ress of the transplant procedure -- and produce an inflammatory molecule called interferon (IFN)-gamma, which helps to activate the auto-reactive T cells. In mice that lack NKT cells or are unable to produce IFN-gamma, the transplanted cells survived. The group went on to show that multiple doses of a drug (call...Liver CRP production linked to atherosclerosis
...hages, expressed CRP mRNA following stimulation by inflammatory molecules. These data highlight a powerful role for the liver in generating the CRP that is associated with atherosclerotic lesions. Nonetheless, we are still left wondering whether CRP is a cause, result, or both of heart disease, as presence at ...Prevalence of drug-resistant gonorrhoea increasing in South Africa
...ed gonorrhoea is a serious condition called pelvic inflammatory disease (PID). In men, if left untreated, gonorrhoea can cause infertility. Prashini Moodley and Willem Sturm (University of KwaZulu Natal, Durban, South Africa) have been testing the susceptibility of N gonorrhoaea to ciprofloxacin in isolates from ...Novartis MS drug shows promising results
...oral FTY720 on reducing both clinical relapses and inflammatory disease activity that we first saw during the six-... The MRI results at 12 months showed low levels of inflammatory disease activity in all FTY720 groups. In patients who switched from placebo to FTY720, the mean num...New immune cell found to be a key to inflammatory diseases
HOUSTON - The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis,...ues. This newly described T cell - which they call inflammatory TH cells (or THi) - produces interleukin 17 (IL-17), a potent cytokine that researchers have already...High fat diet alters hepatic immune system in mice
...y shows that high-fat diets correlate to a chronic inflammatory state in the liver, which promotes chronic liver disease. The researchers suggest a potential mechanism for this outcome: diet-induced depletion of the hepatic NKT cells that balance local production of pro- and anti-inflammatory cytokines. "Further...Fatty foods fight inflammation
...f events in patients might provide a way to reduce inflammatory complications after surgery....UQ leads the State in NHMRC grants
...the implications of these processes for cancer and inflammatory diseases. In particular, her current research looks at the protein known as E-cadherin, which prevents tumour cells from multiplying, but in malignant tumours, this protein malfunctions allowing cancerous tumour cells to spread. This research will h...Erectile dysfunction may signal early atherosclerosis
...ture of atherosclerosis and the relationship to an inflammatory process of the vessel wall. This understanding of atherosclerosis increasingly allows early interventions aimed at the prevention of disease complications," Dr. Schoenhagen said....Trial demonstrates new drug's effectiveness against psoriasis
...eek's issue of The Lancet. Psoriasis is a chronic, inflammatory skin disease that usually needs long-term treatmen...NF alpha. Infliximab is already approved for other inflammatory diseases triggered by TNF alpha, such as rheumatoid arthritis and Crohn's disease, but its safety an...Curcumin halts spread of breast cancer in mice
... so toxic, it activates a protein that produces an inflammatory response that induces metastasis. Curcumin suppres...B (NF-kB) (a powerful protein known to promote the inflammatory response necessary to cause breast cancer to spread) is shut down, cancer strains are unable to grow...Sexes differ in their immune reactions to burnout on the job and depression
...indings show that work-related burnout can lead to inflammatory processes, which plays a key role in the initiatio...s find evidence that men and women differ in their inflammatory reactions to work-related burnout and depression According to a new study from the Journal of Occup...Notch signaling molecule important in type 2 immunity
...lls may lead to diseases characterized by a faulty inflammatory response such as autoimmunity and asthma. Understa...s, such as asthma, autoimmunity, and some forms of inflammatory bowel disease. Drugs that inhibit Notch signaling, called gamma secretase inhibitors, are currently ...UVa Health System wins renewal of $6.2 million grant for Crohn's disease research
...UVa as one of the premier centers for the study of inflammatory bowel disease in the U.S. and worldwide," said Dr....litating, disease characterized by ulcerations and inflammatory lesions throughout the gastrointestinal tract. Symptoms include severe abdominal pain, diarrhea, wei......ege of Health Professions. The study, "Increase in inflammatory cytokines in median nerves in a rat model of repet...lf-regulate their work behavior," said Barr. "With inflammatory proteins in the bloodstream, they began to slack off from completing their tasks." By five weeks t...Diabetes and depression can be a fatal mix
...p together inside of blood vessels, an increase in inflammatory markers, and changes in heart rhythms....What is the best treatment strategy for early rheumatoid arthritis?
A progressive, inflammatory disease affecting the joints and organs, rheumatoid arthritis (RA) claims more than two million Americans, mostly women over age 40, among its victims. While a cure has yet to be found, the treatment of RA patients has changed considerably over the ...