New insight into cause of Crohn's disease
...tment of the disease. Crohn's disease is a chronic inflammatory disorder that causes ulcerations in the small and ... produced much lower quantities of neutrophils and inflammatory mediators when compared with healthy individuals. Cultured blood cells were also abnormal in the pat...Isolated female rats subjected to a 30-minute stressor heal faster than males
...s speculate in the study "Social isolation and the inflammatory response: sex differences in the enduring effects ...minute episode of acute physical stress had on the inflammatory response, the body's innate immune response to bacteria, viruses, and parasites. The authors found t...New insights into the link between rheumatoid arthritis and cancer
An inflammatory disease of the immune system, rheumatoid arthritis... patients with severe RA. Very high and prolonged inflammatory activity, not its treatment, is the major risk factor. Drawing their sample from a national registe...Anti-inflammatory drug's potentially deadly side effect found to be rare
...he drug to treat patients with Crohn's disease, an inflammatory bowel disorder. "Our analysis suggests about one i...i. The drug is a monoclonal antibody that binds to inflammatory immune T cells and prevents them from crossing membranes that protect the brain and the central nerv...Studies report findings on colorectal cancer screening methods and survival rates
...Historically, it has been thought that people with inflammatory bowel disease (IBD) are at a significantly higher risk of developing and dying from colorectal cancer than those who develop it sporadically. However, findings of a study published in the journal Clinical Gastroenterology and Hepatology show that ...Inflammatory biomarker helps identify progressive precancerous lesions in the lung
...e associates measured CRP, lung function and other inflammatory markers in 65 individuals. All participants had at least one abnormal cell site in their lungs (bronchial dysplasia) greater than 1.2 millimeters in size, which was biopsied at the start of the study and re-examined 6 months later. Of the study cohor...Major biomarker candidates for Alzheimer's disease explored
...tau, and phospho-tau. Other biomarkers that target inflammatory and oxidative damage processes may have future potential.In a disease with no known cure and no treatments that can delay onset or prevent progression, prediction of future pathology is particularly important. In "The search for antecedent biomarker...Exposure to fine particle air pollution linked with risk of respiratory and cardiovascular diseases
...ic [arising in or stimulated by nerve tissues] and inflammatory processes," the authors write. "Our findings indicate an ongoing threat to the health of the elderly population from airborne particles and provide a rationale for setting a PM2.5 National Ambient Air Quality Standard that is as protective of their h...Scientists use PET scans to monitor lung inflammation noninvasively
...ion should accelerate efforts to develop drugs for inflammatory lung conditions like cystic fibrosis and pneumonia...lp doctors monitor the conditions of patients with inflammatory lung diseases and should make it easier to test potential anti-inflammatory drugs in trials. "Until ...Research shows fat fuels inflammation killer
... groups, and have measured a variety of markers of inflammatory activation and related these to measures of obesity or fatness such as body mass index (BMI) and waist-hip ratio (WHR). The study clearly showed that the levels of sE-selectin, a marker of inflammation produced by artery vessel walls, are strongly as...BIDMC's Harvey Goldman, MD, receives distinguished pathologist award
...field of gastrointestinal pathology has focused on inflammatory conditions of the esophagus, stomach and intestine...assification of colonic dysplasia that complicates inflammatory bowel disease. A leader among his peers, Goldman has served as president of the New England Society ...Red wine components modulate tissue damage induced by bacteria in gum diseases
...nd in red wine can help in preventing and treating inflammatory periodontal diseases. Periodontitis is a progressi...ed wine polyphenols significantly modulate several inflammatory components released by macrophages (a population of host immune cells) in response to bacterial stim...Resolvin E1 protects against inflammation and bone loss
...oth loss. Gum disease is similar to other chronic inflammatory diseases such as arthritis, where inflammation cau...ent disease in susceptible individuals with a high inflammatory response. Researchers presenting their findings today during the 35th Annual Meeting of the Americ...Refinements and innovations enhance safety, effectiveness
...ry bypass grafting (CABG), but it also provokes an inflammatory response that increases the risk of heart attack a...tion, cardiac surgery subjects the heart itself to inflammatory injury when the blood supply is re-established. The international PRIMOCABG II trial will shed ligh...Asthma risk increased in women with high levels of fat tissue inflammatory protein
Women with high levels of an inflammatory protein produced by fat tissue are at significantl... The researchers measured the levels of leptin, an inflammatory protein that is produced by fatty tissue in the body. Leptin levels were significantly higher among...Combining multiple treatments improves multiple sclerosis therapy
Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (...sease incidence. The authors then treated isolated inflammatory cells called macrophages with these drugs and found that the combination therapy mediated its effect...Crohn's & Colitis Foundation of America selects Wiley to publish Inflammatory Bowel Diseases
...nly peer-reviewed journal dedicated exclusively to inflammatory bowel diseases. Now in its tenth year, the journal provides articles of interest to professionals treating patients and conducting research in this expanding field. Each issue contains articles on clinical and basic science, as well as reviews of tre...Pregnancy research leads to progress on premature delivery
...branes of pregnant women, sometimes fuel a harmful inflammatory response. The inflammation, in turn, may cause the...ria, the TLRs activate and cause inflammation. The inflammatory cells brought in to kill off the infectious microbes may pump naturally occurring hypochlorous acids...The Lancet calls for independent scrutiny of the TGN1412 trial
... men were admitted to intensive care with a severe inflammatory reaction and multi-organ failure. Two remain critically ill. The Medicines and Healthcare products Regulatory Agency (MHRA), who authorised the trial, told The Lancet that the trial protocol specifies that TGN1412 should be given at 2-hour intervals......MS, there is evidence to suggest that a controlled inflammatory response may actually restore damaged myelin and nerve function. Now, in a study appearing online on March 23 in advance of print publication in the April issue of the Journal of Clinical Investigation, researcher Michal Schwartz and colleagues at t...