Wasabi's kick linked to single pain receptor
...rchers report. Acrolein accounts for the toxic and inflammatory actions of tear gas, vehicle exhaust, tobacco smok...nt target of bradykinin, one of the body's natural inflammatory agents that stimulates pain-sensing neurons and leads to hypersensitivity to heat or touch. Mice lac...New family of biodegradable polymers shows promise for intracellular drug delivery
...peutic drugs to the acidic environments of tumors, inflammatory tissues and intracellular vesicles that hold forei...ers don't know yet whether polyketals will be less inflammatory than current polymers used for drug delivery, but expect to evaluate this response within the next y...Targeting the inflamed synovium
...matoid arthritis (RA) is a complex and destructive inflammatory disease. Despite recent impressive advances in disease-modifying antirheumatic drugs and biologic therapies, treatment is not always effective and still has many safety ramifications. Assessment of RA, once dependent on X-ray measurement of cartila...New hope for tissue regeneration and joint repair
...erate cartilage, muscle, and bone in patients with inflammatory and degenerative rheumatic diseases. Samples of periosteal cells were obtained from the tibia of 12 human donors, ranging in age from 24 to 83 years. Following enzymatic release and culture expansion, cell populatio...Combined treatment cuts inflammatory cells in chronic obstructive pulmonary disease
...d fluticasone propionate, can significantly reduce inflammatory cells in the airways of current and former smokers...nificantly reduced the absolute numbers of certain inflammatory cells, including leukocytes, CD8+ cells and CD4+ cells, and caused a reduction in cells expressing g...JCI Table of Contents, April 3, 2006
...mechanism for regulation of the RAS, controlled by inflammatory mechanisms likely to be quite different from those...ng to self Rheumatoid arthritis (RA) is a painful inflammatory disorder of the joints. Now, in a study appearing in the April issue of the Journal of Clinical Inve...Bone resorption cells offer drug targets for osteoporosis, rheumatoid arthritis, and more
...s caused by the interaction of osteoclasts and the inflammatory cytokines produced by the immune system. Dr. Teit...eoporosis in transplant recipients, asthma, lupus, inflammatory diseases and other diseases requiring use of cortisone for therapy. Taking cortisone can lead to bo...FDA grants priority review of Remicade® for children with Crohn's disease
...logic indicated for the treatment of both types of inflammatory bowel disease (IBD) in adults....Cinnamon, cloves improve insulin function, lower risk factors for diabetes, cardiovascular disease
...e body's insulin signaling, glucose transport, and inflammatory response. Dr. Cao says the study provides new biochemical evidence for the beneficial effects of cinnamon in potentiating insulin action and suggests anti-inflammatory properties for the antioxidants in cinnamon. Other researchers involved in the s...A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
...mmation associated with debilitating diseases like inflammatory bowel disease, arthritis and multiple sclerosis, a...rovide a method to treat a wide variety of chronic inflammatory diseases. "It appears that IL-25 has a Jekyll and Hyde personality: it can be helpful or hurtful de...Curry colouring and fat mix could help diabetics
...ver cells to prevent them from producing all these inflammatory compounds." Early results show his method works in mice but he said his grant would validate the best method to use in human trials. The 36-year-old from Kedron said that, if successful, the treatment could combat other diseases such as heart disea...Researchers resolve how COX inhibitors cause heart hazards, and offer alternative treatment strategy
...cyclooxygenase-2 (COX-2) were developed to relieve inflammatory pain as effectively as nonsteroidal anti-inflammatory drugs (NSAIDS), but without one of their major side effects, gastrointestinal bleeding. However, an unexpected adverse cardiovascular effect a higher incidence of myocardial infarction was subse...Inhaled steroids preferred over cromolyn to treat asthma
...d corticosteroids both block the action of certain inflammatory cells in the lungs. Physicians recommend both types of medication for persistent asthma, but individual studies disagree about which type of medication works best, the reviewers found. "The safety of sodium cromoglycate has been well established, but...Researchers reveal lung's unique innate immune system
... Macrophages are white blood cells involved in the inflammatory response throughout the body, cells normally on the alert for invaders to kill. Alveolar macrophages are unique among macrophages in the body, because their activation is inhibited by TGFb, a compound expressed in the lung by epithelial cells. "Beca...Latest issue of Alzheimer's & Dementia explores new ideas for cause, screening and risk factors
...5 years, suggests education, physical exercise and inflammatory load (as shown by tooth loss) as risk factors for ... the authors suggest that further investigation of inflammatory load as a risk factor for Alzheimer's is warranted....JCI table of contents, April 20, 2006
...rface actually promotes development of the chronic inflammatory condition psoriasis, and that the protein connexin...h prevented wound healing and triggered an ongoing inflammatory reaction. The authors concluded that Cx26 expression must be downregulated in utero in order for the...Probiotics ease gut problems caused by long term stress
...bowel syndrome and in the worsening of symptoms of inflammatory bowel disease, such as Crohn's disease and ulcerat...te for space with harmful bacteria and dampen down inflammatory responses, and as such, offer a potentially promising approach to the management of intestinal probl...Blocking key protein reduces inflammatory markers in metabolic syndrome
... action of a critical protein can improve multiple inflammatory pathways in patients with the metabolic syndrome ...lucose intolerance, and abnormal levels of several inflammatory proteins. The occurrence of the syndrome is increasing, and it is estimated to affect more than 50 ...Gene variations linked to brain aneurysms
...Interleukin-6 or IL-6 for short is involved in the inflammatory processes of coronary artery disease and has been implicated in stroke and an increased risk of dementia. The chemical is known to damage brain tissue. The frequency of a particular variation of the Il-6 gene (-572G>C ), which boosts production ...... Yet, questions remain surrounding the role of the inflammatory system in the cartilage destruction following mechanical trauma. Tissue damage typically stimulates an influx of leukocytes, white blood cells known for promoting tissue regeneration and healing--to tissue p...