Doernbecher researchers to study effectiveness of stem cell transplant in human brain
...hout these enzymes or proteins, material builds up inside brain neurons and other brain cells, causing a rapidly progressive decline in mental and motor function, blindness, seizures and early death. This study addresses two forms of NCL: infantile neuronal ceroid lipofuscinosis (INCL) and late-infantile ne...Study puts drug-eluting stents to test in heart attack patients
...the artery wall--prevent a build-up of scar tissue inside the stent, a complication known as in-stent restenosis. These devices have only been rigorously tested in patients with stable cardiovascular disease. The Randomized Comparison of Paclitaxel Eluting Stent Versus Conventional Stent in ST-segment Ele...Drug-eluting stents outperform radiation treatment for coronary restenosis in bare metal stents
...lar brachytherapy, which delivers radiation to the inside of the artery via a catheter. Vascular brachythera... restenosis, when used for initial stent placement inside a coronary artery. The TAXUS-V ISR trial was designed to determine the safety and efficacy of drug-e...Sirolimus-releasing stents more effective than VBT for treating restenosis within a stent
...group, minimal lumen diameter (size of the opening inside the vessel through which the blood flows) was larger in the sirolimus-eluting stent group at 6-month follow-up. "In conclusion, in-stent restenosis following bare-metal stent placement remains a significant clinical problem. While vascular brachythe...Scientists discover how coffee can reduce risk of pancreatitis
...entration is movement of calcium ions from a store inside the cells into the cell water through special chan...s causing the excessive liberation of calcium ions inside the cells, which is where the problem originates. We are also hoping that these findings can be used...Drug-eluting and absorbable stents push interventional frontiers
...ent. Vascular brachytherapy (VBT)--or irradiation inside the narrowed artery--is the only therapy approved by the Food and Drug Administration for in-stent restenosis (ISR), as the renarrowing is called. However, brachytherapy is time-consuming, not widely available, and has been shadowed by complications...Very high-intensity statin therapy shows promise for inducing regression of coronary atherosclerosis
...therosclerosis (the accumulation of fatty deposits inside arterial walls) is generally viewed as a chronic, progressive disease. Prior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of atherosclerosis progression with statin therapy but have not shown convincing evidence of ath...U of M researchers identify cause of memory loss
...he brain; and tau, which forms the tangles bundles inside nerve cells. Ashe's lab proved last year that the tangles are not the cause of memory loss; this latest research shows the plaques aren't a major cause either. People with Alzheimer's disease exhibit memory impairment before they are formally diagnos...Hopkins study shows low-dose aspirin suppresses clumping of blood platelets in both sexes
...hey impede the flow of electricity in a wire probe inside a test tube filled with blood. Moreover, platelet aggregation was largely suppressed in at least three other key pathways related to their function when platelets were stimulated with substances that normally trigger clot formation. Each of these t...A new metal detector to study human disease
...nts of the tiny amounts of zinc ordinarily present inside living cells. The study appears in the current is...Thompson. Thompson explained that almost all zinc inside cells is incorporated into proteins, where it plays many vital roles, such as helping to read the ge...Evanston Northwestern Healthcare first to use latest robotic surgical system
...vements of the miniaturized instruments positioned inside the patient. Two robotic arms, representing the surgeon's left and right hands, hold the proprietary instruments. The instruments -- which have more range of motion than the human hand -- are inserted into the patient through 1-2 cm incisions. A thi...Global program to eliminate elephantiasis has early success in Egypt
...es, which can live and reproduce for several years inside the human body. According to the World Health Organization (WHO), lymphatic filariasis is a leading cause of chronic disability in the world. Policymakers at World Health Assembly meetings in 1997 endorsed filariasis as a candidate disease for globa...Genes and environment interact to promote cancer
..., potently boosted estrogen and progestin activity inside cells. The elevated hormone levels are likely resp...als boost the activity of estrogens and progestins inside cells eight- to 10-fold," said McDonnell. "These data should prompt caution for patients who are exp...PENN surgeons offer transfusion-free heart surgery to all
...ts or adverse reactions, as well as keep the blood inside your own body at all times. You can build it up before the surgery and use the techniques to limit the blood you lose during surgery." In traditional open-heart surgery, on average, one to two units of blood are used in a typical operation, but a pat...Nobel Laureate Eric Kandel condemns 'censorship' of scientists
...th imaging, for example, we have tools for looking inside the active human brain, enabling us to have a new synthesis that wasn't possible years ago." To hear all of Kandel's provocative interview with Science & the City editor Adrienne Burke, visit www.scienceandthecity.org/podcast ....Mayo Clinic researchers identify cell cue for destroying tumors
...help destroy tumors. When this signal is generated inside cells called natural killer (NK) cells, materials are released in the body that induce cell death in cancer cells. Now that this signal has been identified, new strategies can be generated for enhancing the ability of the immune system to kill tumor ...UCI researchers find that, even at rest, men's and women's brains behave differently
...for example, receive strong input from the sensors inside the body. "Throughout evolution, women have had to deal with a number of internal stressors, such as childbirth, that men haven't had to experience," Cahill said. "What is fascinating about this is the brain seems to have evolved to be in tune with ...Wake Forest physician reports first human recipients of laboratory-grown organs
...e main goal of the surgery was to reduce pressures inside the bladder to preserve the kidneys. In addition, urinary incontinence, which was a problem before the surgery, improved in all patients. "It is rewarding when you can see the improved quality of life in these patients," said Atala. The patients wer...JCI Table of Contents, April 3, 2006
... is tightly linked to salt intake and the pressure inside the kidney, suggesting that the RAS is central to controlling body fluid volume and blood pressure. Now, in a study appearing in the April issue of the Journal of Clinical Investigation, researcher Roberto Levi and colleagues at Weill Medical College...Abdominal fat more significant in exercise-induced shortness of breath than overall weight
...abdomen as opposed to visceral fat or fat actually inside the abdominal cavity where the stomach and other organs are located) and the oxygen cost of breathing. It is not yet clear whether increased shortness of breath in these women is simply the result of increased weight and forces on the lungs, or if ...