Tag: "intracellular" at medical news

The unknown risks of arthritis

...blished that TNF inhibitors increases the risk for intracellular infections such as TB. The risk for much more common, yet still serious, infections remains less clear. Studies from clinical practice have shown mixed results, and taken together, clinical trials indicate the possibility for a risk increase of clini...

Experiments with fruit quality improvement lead to new approach for halting spread of cancer cells

...ts, actibind binds actin, a major component of the intracellular structure in plants, interfering with the plants' pollen tubes and halting cell growth. While the Hebrew University researchers were initially interested in the activity of actibind in connection with a horticultural project aimed at improving the...

Elevated testosterone kills nerve cells

...bed in this study occurs through overactivation of intracellular Ca2+ signaling pathways. Overstimulation of the apoptotic program in neurons has been associated with several neurological illnesses, such as Alzheimer disease and Huntington disease....

Clinical study results using Aldagen's product to isolate cord blood stem cells presented at ASH

...nitor cells based on the elevated expression of an intracellular enzyme, aldehyde dehydrogenase (ALDH)....

New class of targeted cancer drugs shows promise in slowing progression of recurrent prostate cancer

..., the binding of these growth factors activates an intracellular signaling pathway that leads to tumor proliferation. While other drugs such as docetaxel have shown to benefit men with advanced prostate cancer, no other second-line therapy (a treatment given when an initial treatment (first-line therapy) does...

A closer look inside our lungs -- Penn researchers develop 2 novel imaging techniques

...wn to an even smaller level -- to the cellular and intracellular level. Investigators have figured out a way in which they hope to look for a "marker" of disease inside the body. In animal models, they are injecting polarized carbon-13-labeled molecules and watching its conversion in real time. They can take image...

A new, nanoporous ceramic filter offers hope to kidney-dialysis patients

...f a four-hour dialysis session to rid the blood of intracellular toxins. "Kidney patients do not die from dialysis but from cardiovascular diseases caused in part by nutrients being leaked out of the body," says Van Geertruyden. "Five years is the average survival rate for dialysis patients. We hope to improve t...

The Burroughs Wellcome Fund awards $8 million to infectious disease investigators

...ution-based identification and functional study of intracellular host-virus interactions Dorian B. McGavern, Ph.D. The Scripps Research Institute Chemical and molecular approaches to probe viral pathogenesis in real time Yorgo Modis, Ph.D. Yale University Cell entry and innate immune recognition of flaviviruse...

Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus

...for the cell nucleus. ZMPSTE24 is a membrane-bound intracellular zinc metalloproteinase that is required for the conversion of prelamin A to mature lamin A. Interestingly, researchers found that the accumulation of prelamin A was exaggerated in cells that contained half the normal amount of ZMPSTE24. Genetic d...

Penn study finds pro-death proteins required to regulate healthy immune function

... both findings is based on how Bax and Bak work on intracellular membranes. Specifically, the team found that whe...d that the amount and rate of calcium release from intracellular stores was altered in the mutant cells. The inadequate calcium signals were unable to stimulate t...

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