Researchers link metal ions to neurodegenerative disease
...niversity has defined for the first time how metal ions bind to amyloid fibrils in the brain in a way that...ns, are found naturally in the brain, as are other ions such as zinc and iron. Increasing evidence now links these naturally occurring ions to amyloid assem...Scientists train nano-'building blocks' to take on new shapes, as reported in Science
.... The technique relied on divalent organic counter ions and solvent mixtures to drive the organization of the block copolymers down specific pathways into snake-like, one-dimensional structures. Much of the research was conducted using the high-powered microscopes in the UD College of Engineering's W. M...'Cars' imaging reveals clues to myelin damage
..., Ind. -- Researchers have discovered that calcium ions could play a crucial role in multiple sclerosis by...heath degradation by allowing an influx of calcium ions into the myelin. The increased concentration of calcium ions then activates two enzymes - calpain an...Mercury's link to heart disease begins in blood vessel walls
...nic chemicals that bind with and remove free metal ions from substances. The power of methylmercury chloride to activate the enzyme was also affected by antioxidants, including vitamin C, suggesting that this form of the metal generates free radicals. This is the form of mercury most closely associated...JCI table of contents -- May 17, 2007
.... The transport of potassium (K) and chloride (Cl) ions in and out of red blood cells is a major determinant of the cells volume and density. Overactivation of K-Cl cotransport out of red blood cells leads to red blood cell dehydration and distortion (sickling). In a study appearing online on May 17 in ...Mice with a migraine show signs of brain damage
...r from CSD, which throws the proportion of crucial ions like potassium and sodium out of balance, taking away the brains ability to function efficiently. This change in the proportion of chemicals gradually sweeps across the brain like a slowly spreading wave. The brain, in turn, is under tremendous str...Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment
...ients. The disruption to this protein that conveys ions from lung cells to airways causes thick mucus to b...healthy lungs, CFTR allows the passage of chloride ions (and accompanying water) into airways, creating a thin layer of fluid to keep airways clear. However...Disposable sensor uses DNA to detect hazardous uranium ions
... sensor arrays that detect and quantify many metal ions simultaneously....Picture this: FSU professor's research could lead to vastly improved medical imaging
... known. "Fe8 is a molecule made up of eight iron ions that form a tight molecular bond," Dalal said. "It has a powerful magnetic field, which is obviously important in generating a very clear image with an MRI device. What's more, Fe8 is non-toxic and water-soluble, making it safe for injection into the...Einstein's tea leaves inspire new blood separation technique
...le. A voltage is applied to the needle, generating ions around its tip that repel the oppositely charged ions close to it. This creates an airflow known as "ionic wind" that sweeps across the surface of the blo...Chemists make tiny molecular rings with big potential
...o bind their rings to other charged atoms, such as ions of potassium and lithium....Antiprotons 4 times more effective than protons for cell irradiation
...rotons with another form of treatment using carbon ions will begin next month at GSI (Gesellschaft fr Schwerionenforschung) in Germany. Further tests are planned to fully assess the effectiveness and suitability of antiprotons for cancer therapy, and to assure that less damage is caused to healthy tissues...Light-sensitive photoswitches could restore sight to those with macular degeneration
...t, the molecule kinks and pulls the plug, allowing ions to flow through the channel and activate the nerve cell. Green light unkinks it and replugs the channel, blocking ion flow. Isacoff said that this same photoswitch could be attached to a variety of proteins to push or pull them into various shapes, ......t with metallic iron or a solution containing iron ions with a twofold positive charge. In contrast, solut...objects made of iron, the required doubly negative ions are formed when perspiration on the skin corrodes the iron. Rubbing blood over skin results in a ...New mechanism underlying pain found
...st within a cell that allow the passage of certain ions into a cell to regulate activity. It is believed t...d cation channels) -- allow the entrance of sodium ions into the cell based on the configuration of the protein. Entry of sodium ions can trigger electrical...Rochester researchers join federal initiative to improve drug safety
...ls are protein structures that control the flow of ions responsible for producing the electrical activity of the heart. Interference with these structures diminishes the cells' ability to "recharge" between contractions, which, over time, may lead to lethal electrical dysfunctions of the heart. Rochester...Researchers examine why food tastes bad to chemotherapy recipients
...ponents to the metallic flavor the taste of metal ions on the tongue and the production of metal-catalyzed odors in the mouth that create a retro-nasal effect. "I am attempting to gain a better understanding of the metallic sensation, its prevention, and application to human health," Dietrich said. Alo...Molecular medicine comes to the rescue
...orm a channel that regulates the flow of potassium ions in and out of the insulin-producing beta cell. ...sium channel to close. After it closes, potassium ions accumulate within the cell. When they reach a certain level, they trigger the opening of calcium ch...Purdue chemical-analysis method promises fast results
... surface of the sample being tested, the hydronium ions transfer their extra proton to molecules in the sa...nto the mass spectrometer, where the masses of the ions are measured and the material analyzed. DESI has been used to accurately detect cancer in human live...Scientists discover how coffee can reduce risk of pancreatitis
...n calcium ion concentration is movement of calcium ions from a store inside the cells into the cell water ...annels causing the excessive liberation of calcium ions inside the cells, which is where the problem originates. We are also hoping that these findings can ...