Lowering blood pressure more important than drug class in preventing kidney disease
...ices to treat high blood pressure in patients with kidney disease may not be the best option, according to a...e blood pressure-lowering therapy in patients with kidney disease. Doctors have assumed that these drugs have specific effects to protect the kidney beyond th...JCI table of contents: December 8, 2005
...org/article.php?id=21759 PHYSIOLOGY Inhibiting kidney protein USAG-1 may help decrease dialysis dependen...from Kyoto University report that mice lacking the kidney protein USAG-1 are resistant to kidney injury. The authors show that USAG-1 inhibits the activity of...Risk of second cancer after breast cancer
...as also seen after endometrial cancer. Colorectal, kidney and postmenopausal breast cancer appear to share obesity as a risk factor, while ovarian cancer and breast cancer seem to have a genetic predisposition in common. The study found an excess of ovarian cancer already within one year of breast cancer di...Blood test can accurately diagnose heart failure in patients with kidney dysfunction
...atients remains effective in patients with chronic kidney disease. The study also demonstrates that the tes...atients at a higher risk for death, independent of kidney dysfunction. The report from investigators at the Massachusetts General Hospital (MGH) will appear ...Toward the future of cancer prevention
...ty, pharynx, larynx, esophagus, pancreas, stomach, kidney and bladder, among others. The American Cancer Soc...d cancers such as those that occur in the bladder, kidney and esophagus, and to other non-smoking related cancers such as melanoma, brain, prostate and lympho...Mayo Clinic finds kidney cancer patients are unlikely to respond to potential treatment drug
... grade renal cell carcinoma -- the most aggressive kidney cancer. Results of the study are published in the...ing does not seem like good news for patients with kidney cancer," says Bradley Leibovich, M.D., Mayo Clinic urologist and lead investigator of the study, "it...Early, aggressive treatment of type 1 diabetes lowers risk of cardiovascular disease
... glucose control prevents or delays eye, nerve and kidney damage common complications of type 1 diabetes. A...s. Diabetes is the most common cause of blindness, kidney failure and amputations in adults and a major cause of heart disease and stroke. "We don't know wh...Tight glucose control cuts heart disease by half in type 1 diabetes
...ose control prevents or delays the eye, nerve, and kidney complications of type 1 diabetes. However, resear...glucose control greatly lowers the eye, nerve, and kidney damage of type 1 diabetes. At the end of the study, HbA1c readings averaged 7 percent in the intens...Blocking previously unrecognized links between inflammatory systems could make COX-2 inhibitors safe
...ms in both immune system cells and human embryonic kidney cells by adding substances known to activate these enzymes -- for example, LPS-IFN-gamma, a combination of a component of some infectious bacteria membranes and an immune system protein that targets viruses and tumors. When the investigators broke ap...Misdosing common for powerful anti-clotting drugs
...re time clarifying information such as weight and kidney function which are necessary for accurate dosing....atients, such as women, the elderly, or those with kidney insufficiency or low body weight," she said. Bleeding episodes typically involve oozing at site of c...New UCSF study finds that obesity is a risk factor for kidney failure
...g obese and developing end-stage renal disease, or kidney failure. The long-range study found that the obese have up to a seven times greater risk of kidney failure than normal weight people, suggesting that obesity should be considered a risk factor for th...Doctors at UVA health system search for new treatments for diabetic kidney disease
...SRD) and were living on chronic dialysis or with a kidney transplant, according to the American Diabetes Ass...rses and physicians is stopping the progression of kidney disease in its tracks in people with diabetes, potentially saving thousands of lives. Research on o...Abdominal chemo boosts survival in ovarian cancer patients
...nts with adhesions or surgical complications, poor kidney function, and those who have had the left side of their colon removed during surgery are not ideal candidates for IP therapy. It also is not clear whether the procedure has any benefit for recurrent disease or patients with large amounts of residual ...Difficulty in treating older hepatitis C patients with combination therapy
...t that older patients had higher rates of impaired kidney function and high blood pressure may have led to more frequent adverse effects. In addition, they note that patients were given high-dose induction therapy of standard interferon, which may render them more susceptible to adverse effects than HCV pat...UCLA paper examines how one disease may prevent another
...from severe caloric or protein restriction include kidney failure, type-II diabetes, inflammatory bowel dise...t Babies Hospital in New York City. One case was a kidney disease patient with nephrosis who was unresponsive to medications but went into remission after con...Genes' influence on common drugs may affect health-care quality, cost
...ointestinal bleeding, cerebrovascular hemorrhages, kidney impairment, dizziness, low blood pressure and slowed heart beat. The number and severity of adverse reactions to the drugs surveyed was not measured in this study; however, a 1998 study ranked adverse drug reactions as among the top ten leading cause...Study shows inhaled medicine improves survival for lung transplant patients
...other solid organ transplants, including liver and kidney transplants," says Dr. Iacono. Years of work led up to the clinical study. Dr. Griffith began doing basic research on the concept of an inhaled form of cyclosporine in 1988 while he was on the faculty of the University of Pittsburgh School of Medici...Mayo collaboration identifies gene in childhood kidney disease
...ified a new gene involved in causing the inherited kidney disorder, Meckel-Gruber syndrome (MKS). Children w... disorders such as more common forms of polycystic kidney disease (PKD). PKD accounts for more than 5 percent of end-stage kidney disease in the United States...International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy
...ase in major complications such as cardiovascular, kidney and liver diseases in the participants on the drug conservation arm. These complications have been associated with ART, and it was hoped that they would be seen less frequently in those patients receiving less drug. Although the risk-to-benefit ra...Metabolic syndrome identified as risk factor for kidney-pancreas transplant patients
...ents has identified a new risk factor for impaired kidney function, which may help physicians refine their t...isease, is also a risk factor for deterioration of kidney function in simultaneous kidney-pancreas transplant recipients. The risk is especially high when the...