Other highlights in the October 5 JNCI
...ental factors in infancy may influence cancer risk later in life. For example, breast feeding is associated...and insulin-like growth factor 1 (IGF-1) levels in later childhood, and height and IGF-1 levels have been associated with the risk of some adult cancers. How...Model predicts risk of breast cancer for young women treated for Hodgkin lymphoma
...mulative absolute risk of developing breast cancer later in life. This risk increases with age at end of follow-up, time since diagnosis, and radiation dose, according to a new study in the October 5 issue of the Journal of the National Cancer Institute. Due to advances in the treatment of Hodgkin lymphoma...Test predicts risk of liver scarring after transplant, study shows
...in (alpha-SMA) could predict which patients would later develop fibrosis. The study involved 46 patients with hepatitis C virus who received liver transplants between 1997 and 2001. The patients were divided into two groups: those who developed advanced fibrosis within two years of liver transplant and t...New study at UNC shows concussions promote dementias in retired professional football players
...fer dementias such as mild cognitive impairment in later life, a new study suggests. The study, conducted by University of North Carolina at Chapel Hill researchers and colleagues, found that retired National Football League players also faced a 37 percent higher risk of Alzheimer's than other U. S. males ...EBCT scans trump angiography at detecting killer heart defect
...phy for chest pain or shortness of breath and then later underwent an EBCT. In half of the patients, angiography showed a congenital abnormality for example, a left coronary artery originating from the right side of the aorta, or vice versa. EBCT also detected the abnormalities, but in more than a third ...CT colonography versus colonoscopy for colorectal cancer
...d deaths from polyps not seen with CT, which would later become malignant. (Colonoscopy is slightly more sensitive than CT colonography, and could be expected to detect a certain number of polyps that the CT method would miss.) New technologies are always attractive. Because CT colonography does not physic...Midlife obesity may be associated with risk of dementia and Alzheimer's disease
...bese at midlife had an increased risk for dementia later in life compared to individuals of normal weight, ...ife was not significantly associated with dementia later in life. "This study shows that obesity at midlife may increase the risk of dementia and AD later in...Eyes may provide window to future strokes
...all blood vessels in their eyes are more likely to later suffer a stroke than people without these signs. The results held true even after researchers took into account traditional risk factors for stroke such as smoking and high blood pressure, according to the study published in the October 11, 2005 issu...Study finds surprising links between depression, suicide, and epilepsy
...eople who develop depression have a higher risk of later experiencing a first seizure. While neuroscientist...ht change) did not predict a greater likelihood of later seizures. While this finding clearly suggests common underlying brain mechanisms for suicidal behavi...Study finds gender differences in reported childhood sexual abuse
...t that they have symptoms of sexual dysfunction in later life. "Females reporting both non-penetrative and penetrative sexual abuse experiences are substantially more likely to report many symptoms of sexual dysfunction." The National Health and Medical Research Council-funded study is one of the first t...End-stage renal disease incidence, prognosis improving for patients with diabetes
...or patients diagnosed as having type 1 diabetes in later years. The risk did not differ significantly between sexes. Patients with ESRD had 13.1 times the risk of death compared with other patients with type 1 diabetes when adjusting for age, sex, and time period of diabetes diagnosis. "This emphasizes the...Early life stress can lead to memory loss and cognitive decline in middle age
... of Neuroscience. "The loss of cognitive function later in life is probably a result of both genetic and e...larly of early life stress, on learning and memory later in life. These studies point to the development of new, more effective ways to prevent cognitive imp...Innovative gel reduces post-operative pain
... In some cases, patients were asking only two days later if they could return to work."...Hodgkin disease survivors face higher risk for stroke later in life
...surviving childhood Hodgkin disease suffer strokes later in life at rates about four times that of the gene...ts with cancer, little research had linked strokes later in life to cancer. Testing that hypothesis on all survivors of childhood cancer was too impractical,...Big and fast growing infants at greater risk of later obesity
...es the relation between infant size and growth and later obesity. Researchers analysed 24 studies which as...e and growth and the development of obesity at any later age. They found that the heaviest infants, those with the highest body mass index, and those who gai...Kids who drink early in life: What does it mean for their future?
...or." Yet the relationship between an early AFD and later problems is not one of "cause and effect," said St...tionship between drinking early in adolescence and later negative outcomes in drinking is a simple observed correlation," observed Arndt, also with the Iowa ...New rheumatoid arthritis drug developed at UCSD promises improved treatment options
...ollege of Rheumatology (ACR) from the beginning to later points in the trial. For instance, "ACR 20" indicates a 20% improvement in standardized symptoms. ACR 20 response was in the 50-55% range; ACR 50 in the 30-40% range; and ACR 70 in the 15-20% range of patients completing the trial. Rheumatoid arthr...Alcoholics Anonymous and treatment seem to work best together
...ore likely to achieve remission for up to 15 years later than are individuals who obtain professional treatment alone. Finally, individuals who have achieved remission but who discontinue participation in AA are at increased risk for relapse; individuals who have not stopped drinking and who discontinue p...Fox Chase study shows TURP patients with intermediate PSA should be considered high-risk
...ients who had a pretreatment PSA of 10 to 19.9 who later recurred. There was no strong relationship between the surgery and recurrence for patients with a pretreatment PSA of less than 10. As D'Ambrosio explained, "Patients with a pretreatment PSA of 10 to 19.9 were more likely to recur if they had prior ......ments provide much-needed options for treating the later stages of diabetes (Editorial, p. 609). However, until development of "precise molecular targets" for type 2 diabetes, lifestyle choices (increasing exercise and reducing weight) will be the cornerstone of managing this debilitating and increasingly ...