Staying alert during class: Self-applied acupressure may reduce sleepiness
...tudy showed that a stimulation acupressure regimen leads to a statistically significant reduction in sleepiness compared to an acupressure treatment that focuses on relaxation," says Richard E. Harris, Ph.D., research investigator in the Division of Rheumatology at the U-M Medical School's Department of In...Penn researchers discover a molecular pathway that leads to recurrence of breast cancer
...tant aspects of molecularly targeted therapies and leads to the dramatic regression of tumors to a clinically undetectable state. Nevertheless, residual tumor cells lie in a dormant state and later grow out after a month to a year in the mice. Using microarrays, Chodosh's team compared recurrent tumors wi...New online atlas provides collective maps of human brain folds
...dividual brain are in the crumpled state, and this leads to a dramatic improvement in the quality of the results." Initially based on MRI scans of 12 healthy people gathered by Randy Buckner, Ph.D., associate professor of neurobiology and of radiology, PALS now includes data from 60 additional scans. To g...Hopkins experts highlight strategies to raise levels of so-called good HDL cholesterol
...focused heavily on lowering LDL cholesterol, which leads to plaque formation and narrowing of the arteries that can cause heart attack. "We have reached a turning point in the prevention of coronary heart disease from an emphasis during the last 15 years on lowering LDL cholesterol levels to an emphasis ...Polar explorer delivers rare snow-depth data to ESA for CryoSat validation
...oticed is that there are more frequent but smaller leads (stretches of open water, sometimes covered with v...ny expedition we expect to swim across those small leads in our dry-suits. Sometimes the fresh leads worked in our favour serving as a highway when they were...Hebrew University receives its largest NIH research grant ever -- $5.6 million biodefense award
...s elicit a vastly exaggerated immune response that leads to death. The researchers used this insight to design peptides (short stretches of protein) that block this harmful response in animals, thereby protecting and rescuing them from lethal toxic and septic shock. What remained was an immune response th...Post-stroke tests not used often enough, especially in women
...lly women." Morgenstern, a stroke neurologist who leads the Brain Attack Surveillance in Corpus Christi, or BASIC, study from which the new data were gathered, is a professor in the Departments of Neurology, Neurosurgery and Emergency Medicine at the U-M Medical School and a professor of epidemiology at t...Flavanols key to potential chocolate benefits
...not the chronic consumption of flavanol-rich foods leads to sustained increases in endothelial function, and the prevention of future cardiovascular events. In particular in smokers, it is unlikely that cocoa can completely attenuate the deleterious effects of continued smoking," Dr. Heiss said. Dr. Heiss ...National funding goes to Johns Hopkins to advance research on stem cell therapies for heart attack
...t Joshua Hare, M.D. Hare, a professor of medicine, leads the project to evaluate adult mesenchymal stem cel...ange, chief of clinical cardiology at Hopkins, who leads research efforts into ischemic heart disease and adult congenital heart disease, "This is an incredi...Promote use of drugs to prevent AIDS infection, researchers urge
...t go away -- at least no time soon. The virus that leads to AIDS, human immunodeficiency virus, or HIV, caused an odd illness that was a complete medical mystery only about 25 years ago. Now, HIV infects more than 40 million people around the globe, and each day, some 14,000 more people pick up that infect...Evidence of a new hereditary joint disorder
...ammation. The increased stress on the bones often leads to joint damage. In this novel syndrome, cartilage de-bonds and strips away at a radical rate, leaving bones completely unprotected and joints exceptionally susceptible to shattering. "Further studies elucidating the mechanisms leading to ...Synthetic protein eases arthritis symptoms in mice
...y. In ALPS, the signal pathway interrupted by PLAD leads to disease symptoms. But, the scientists reasoned, PLAD might also be able to block a related cell surface receptor--one involved in passing signals that lead to inflammation. In theory, inhibiting this pathway might benefit people with rheumatoid ar...Researchers win Nobel Medicine Prize for discovering cause of ulcers
...at H. pylori survives in such an environment and leads to ulcer disease. The findings led to the conclusion that once the bacteria is eradicated, ulcer disease is cured. More information about peptic ulcer disease is available in the Patient Center of the AGA Web site at www.gastro.org/ulcers ....Hepatitis C drug proves cost-effective in helping patients with treatment-induced anemia
...Hepatitis C, can cause anemia, which traditionally leads to dosage reduction and diminished treatment compliance by patients. Practice guidelines suggest that patients with anemia receive a drug called erythropoietin, which helps prevent treatment-induced anemia by increasing the number of red blood cells ...Biomarkers used to predict recurrent disease in hepatitis C transplant patients
... begins with mesenchymal and/or HSC activation and leads to the development of fibrosis. They speculate as to what the trigger might be and how it might explain the mechanism of liver disease, examining risk factors for recurrent HCV that might offer clues, as well as substances such as viral proteins and ...Special issue on cystic fibrosis in The Journal of Pediatrics
...ces the concept that unwarranted variation in care leads to adverse outcomes in healthcare and that it is possible to improve results through system-based changes that support evidence-based, patient-centered care. The title of the article is "Improving subspecialty healthcare: Lessons from cystic fibrosi...Mayo Clinic research collaboration discovers why some DNA repair fails
... which appears to be the underlying condition that leads to the repair defect. The commentator notes that the finding helps provide "the first clues for understanding the expansion" phenomenon, and that the significance is that "expansion of simple, primarily triplet DNA repeats seems to be responsible for...Use of kidney paired donation for incompatible donors could expand donor pool
...ed concerning conventional donors. Paired exchange leads to additional concerns. For example, what if one kidney fails early but the other functions well? Those involved in such programs must pay careful attention to the informed consent process and should be conducting formal follow-up studies of donors."...Mechanism controlling DNA damage response has potential novel medical applications
...o the generation of genetically altered cells that leads to cancer. The St. Jude team showed that the competing proteins, ribosomal protein L26 (RPL26) and nucleolin, vie for control of the messenger RNA (mRNA) that codes for p53. mRNA is the decoded form of a gene that acts like a blueprint that the cell'......sebah said it provides new insight into studies he leads on the genetics of obesity. "Now that we have iden...h and the large-scale, family-based study Kissebah leads with TOPS members. This study population is largely of Northern European ancestry and has a high inc...