NCI grants $12.1 million for USC center to study obesity and cancer
...associate director of the USC TREC Center and also leads the center's training and career development component. Bernstein is known for her extensive studies examining links between hormone exposure, obesity and physical activity and cancer risk. "We know that being overweight or obese raises risk for seve...Physician pay-for-performance programs may produce little gain in quality
...few studies demonstrating that pay-for-performance leads to improved quality of care. Meredith B. Rosenthal, Ph.D., of the Harvard School of Public Health, Boston, and colleagues conducted a study on the impact of a prototypical physician pay-for-performance on quality of care within one of the nation's la...Researchers disprove 'fat redistribution syndrome' among men taking HIV drugs
...ibution syndrome," in which HIV therapy supposedly leads to an increase in visceral fat, or fat inside the abdomen -- which is associated with an increased risk of cardiovascular disease -- along with a concomitant loss of fat in the face and limbs. The syndrome is known among AIDS patients and care provi...Proteome Systems signs agreement with Prince Henry's Institute for Ovarian Cancer Diagnostic Test
...gnostic test. Associate Professor David Robertson leads the team at PHIMR that has previously developed a test to diagnose ovarian cancer (Robertson et al., 2002; Robertson and Oehler, 2005). The test is useful for initial diagnosis and monitoring recurrence of the disease in post-menopausal women, but it...Elevated blood levels of a protein are linked to asbestos-induced cancers
...d nonmalignant disease, such as inflammation which leads to scarring in the lung and plaques on the lining surrounding the lungs; 45 were current or former smokers, who had no previous exposure to asbestos; and 76 patients suffered from pleural mesothelioma and were undergoing surgery. Those individuals e...Work on cancer-killing compound nets FSU professor major grant
... on the Florida State University campus, a chemist leads a team of researchers in a quest to develop synthetic versions of rare natural substances. If all goes well, the team's efforts could pay off in the form of the next generation of cancer-fighting drugs. Such research often is a long, laborious proces...Enzyme complex thought to promote cancer development can also help prevent it
... biomarker in question - an enzyme known as EZH2 - leads a duplicitous life. In its "native" state, the enz...ms of EZH2 after they identified the "switch" that leads to its phosphorylation - the well-known culprit Akt, an enzyme that has already been associated with...Kids who drink early in life: What does it mean for their future?
..., we do not know how it fits into the process that leads to problem drinking." "Complicating the relationship of early AFD to later negative outcomes is the fact that many of the risk factors for early AFD may themselves be directly related to these same negative outcomes," added Kuperman. "The goal of th...Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis
...mally thick, sticky mucus that clogs the lungs and leads to life-threatening lung infections. Although many lung bacteria are prevalent with the disease, in teens and adults, the Pseudomonas aeruginosa bacteria appears as the most prevalent cystic fibrosis pathogen and is strongly associated with respirato...HIV patients face discrimination from doctors
...RAND health researcher. "We need to focus on what leads patients to perceive discrimination, whether real or misunderstood, and address it." Among those reporting perceived discrimination, they tended to report less access to care and less trust in their care providers, as well as lower ratings for the qu...Dual therapy works best for controlling asthma
...thma attacks. But the combination therapy "clearly leads to greater improvement in lung function and symptoms than a two- to two-and-a-half-fold higher dose of inhaled corticosteroids," according to Greenstone. There was a 12 percent increase in symptom-free days among patients taking LABA and steroids, co...Qld Brain Institute gains $650,000 spinal research bequest from courageous Lisa Palmer
...r our discovery that inhibiting the molecule EphA4 leads to spinal cord repair. "Lisa's bequest will help us attain the goal of commencing human clinical trials in 2008," Professor Bartlett said. Professor Bartlett and Professor Andrew Boyd at the Queensland Institute of Medical Research will work with D...Flavonoids may inhibit prostate cancer
...tate cancer by shutting off the IGF signaling that leads to prostate cancer cell growth and/or development," Gupta said. "Our findings suggest that apigenin could be developed as a promising agent against prostate cancer," Gupta said. "The next step is to evaluate apigenin action on other molecular pathway...Columbia study shows how doctors may manage blood glucose levels during heart surgery
...ur ultimate research goal is to study if aprotinin leads to better outcomes in diabetic patients undergoing CABG surgery," said Robert J. Frumento, Ph.D., lead investigator of the study and researcher at the department of anesthesiology at Columbia University Medical Center. "The next step will be to cond...Can bench pressing reduce or prevent lymphedema symptoms in breast-cancer survivors?
...ly regulate the fluid in their affected arm which leads to swelling that can range from mild to extensive (bordering on elephantitis) and quite disfiguring. "Statistically, this is a public health problem," says Schmitz. "It affects up to one-half of the nearly two million breast-cancer survivors alive i...A new blueprint to aid physicians in predicting risk for type 1 diabetes
... of Pittsburgh. "Our study and the new research it leads to will help us better predict risk of type 1 diabetes and identify those who can be involved in major trials in the United States and around the world." Dr. Pietropaolo, who also is an associate professor of pediatrics, medicine and immunology at th...Novel discovery of 'DCDC2' gene associated with dyslexia
...hers also found that a genetic alteration in DCDC2 leads to a disruption in the formation of brain circuits that make it possible to read. This genetic alteration is transmitted within families. "These promising results now have the potential to lead to improved diagnostic methods to identify dyslexia and...New clues into causes of scleroderma
...ecome destabilized, a complex process ensues which leads to the excessive TGF-beta pathway activation, and consequent accumulation of collagen, the primary component of fibrotic tissue. "We've learned in our previous studies that the treatment of individual cells with paclitaxel helps stabilize microtubule...Causes of primary biliary cirrhosis
...patology . PBC is a rare autoimmune disease which leads to liver failure. The cause of the disease is unknown. It is more prominent in women, and researchers have found instances of familial clustering, as well as association with urinary tract infections, tobacco smoking, and estrogen use, though some of......ne, does," said Ms. Reichert. "This misinformation leads many smokers to smoke 'light' cigarettes, thinking they will inhale less nicotine. In reality, smokers tend to smoke more light cigarettes and inhale more deeply to get nicotine from light cigarettes, resulting in a significant amount of harmful chem...