Prostate cancer test affected by demographic and lifestyle factors
...ntration alone causes too many false positives and leads to many unnecessary tests, such as biopsies and transrectal ultrasounds. Investigators continue to refine the test, including developing calculations such as PSA velocity, PSA density, and age-specific PSA, or other tests such as percent free PSA. Ho...Evidence links cocaine abuse and Parkinson's disease
...uld then cause damage in the substantia nigra that leads to Parkinson's disease. The study also found that cocaine exposure decreased the number of certain dopamine receptors called D2 autoreceptors. These autoreceptors control the production and/or release of dopamine; when they are in short supply, the ...Toward the future of cancer prevention
...the future of cancer prevention," Lippman says. He leads an effort at M. D. Anderson and several other canc...on advances in the coming years, we have promising leads from the laboratory that will enable us to conduct even better and more informative trials in the fu...Federal grant funds research on novel HIV therapy
...earcher at The Children's Hospital of Philadelphia leads a multi-center $6.7 million program project grant recently awarded by the National Institute of Mental Health (NIMH) to explore a novel approach to HIV treatment. Encompassing basic science research, animal studies and clinical trials in adult patien...Smoking associated with severity of psoriasis
...answer the question, however, of whether psoriasis leads to smoking or smoking exacerbates psoriasis." "The current issue of the Archives demonstrates that psoriasis remains a therapeutically and intellectually challenging disease," he concludes. "As research and development continue, we undoubtedly will ...Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke
...of these receptors by NMDA, such as during stroke, leads to nerve cell damage. In mice that had first received the EP1 stimulator ONO-DI-004, the area of brain damage was more than 28 percent greater than in control animals. The volume of damage in mice treated first with the EP1 blocker ONO-8713 was only...Successful treatment for acute heart failure remains elusive
...refore oxygen to peripheral tissues and organs and leads to over one million hospitalizations each year in the United States. "We've been successful in finding ways to treat chronic heart failure," says Dr. Gheorghiade. "And, on the surface it looks like we're successful at treating ACHF. Patients are tr...Free care by Florida emergency physicians climbs faster as uninsured patient visits increase
...public nonprofit, private nonprofit or for-profit leads to very different levels of uncompensated care for hospitals, it did not determine the levels of uncompensated emergency physician care. Emergency physician groups providing the highest levels of free care tended to practice in urban hospitals servin...Role of nervous system in fatal heart rhythm under study
...o longer pump blood to the rest of the body, which leads to sudden cardiac death without defibrillation a successful emergency shock to jump start the heart back into a regular beat. Studying those electrical signals is what will lead to better medical equipment, Dr. Schumacher says. Traditional cardiac t...Pediatric oncologists should help with difficult decisions
...Conveying information in simple and clear language leads to better decision-making. When parents understand they are more likely to have an opinion. Clinicians should also explore what matters to the patient to make it easier to help make the decision....Radiotherapy advance points way to noninvasive brain cancer treatment
...ent with the maximum tolerated dose - all of which leads to a painfully low quality of life. Because of this, researchers are racing to find better therapies to stop or slow GBM. In the Jan. 1, 2006 issue of the journal Clinical Cancer Research, Gelsomina "Pupa" De Stasio, professor of physics at the Univ...Alcohol-deterrent drugs help patients achieve high rates of long-term abstinence
... abstinence achieved with disulfiram automatically leads to the consolidation of the habit of abstinence. Practice makes perfect. The longer people abstain, the longer they will abstain. In addition, deterrent drugs clearly do deter. Supposedly deterrent drugs also deter but they only deter because...Oral contraceptive pill may prevent more than pregnancy
...rculation. The combination of these two mechanisms leads to low circulating levels of "unbound" or "free" testosterone....UCSD laser technique sheds light on strokes
...the more complicated topology of the blood vessels leads to the counterintuitive result that blood flow in some downstream vessels reverses direction to compensate for the blockage." In the paper, the researchers discuss how this result can explain the observation, by clinicians, that certain regions of th...Cell stress protein linked to aggressive breast cancer
...a key molecular pathway, the MEK-ERK pathway, that leads to unrestrained cell growth in cancer, and that drug inhibitors of this pathway block the cancerous effects of alphaB-crystallin. "Currently, we don't have any targeted treatments like tamoxifen or Herceptin for the aggressive type of breast tumors ...5th European Breast Cancer Conference (EBCC)
...ychological care, diagnosis and treatment Recent leads on possible causes of breast cancer will be presented along with updates on genetics, proteomics and tumour imaging Nearly all the data at the four-day conference is as yet unpublished and being presented for the first time Daily press conference...People who restrict calories have 'younger' hearts
...sue damage and associated adaptative fibrosis that leads to premature and accelerated tissue and organ hardening," Dr. Fontana said. Gary Gerstenblith, M.D., F.A.C.C., from the Johns Hopkins Hospital in Baltimore, Md. wrote in an editorial in the journal that the study is the first to describe the effects...Annals of Internal Medicine tip sheet for Jan. 17, 2006
...) In other words, what is it about being poor that leads to the biological precursors of death after myocardial infarction?...Penn State selected for DHS National Visualization Team
...hwest National Laboratory in Richland, Wash. PNNL leads the Department of Homeland Security's National Visualization and Analytics Center, ( http://nvac.pnl.gov/ ) or NVAC, which is bringing academic expertise to the nation's efforts to discover information that may warn officials of a terrorist attack. ...Stanford study of owls finds link in brain between sight and sound
...nderstanding the mechanisms of attention naturally leads to the possibility of applying their knowledge to human disorders of attention, learning and schizophrenia. "If you understand mechanistically how something works, then you will know how best to fix it," said Knudsen. "It's like with a car; if you kn...