Mayo researchers lead team that discovers role of dendritic cells in childhood autoimmune disease
...ents -- a discovery that suggests they are tightly linked to initiation of the disease process. The finding opens new possibilities for designing better treatments for JDM, and possibly for other related diseases such as multiple sclerosis, rheumatoid arthritis and lupus. The Mayo Clinic-led research team ...'Sharp' older brains are not the same as younger brains
...an did younger rats on a synaptic receptor that is linked to a common mechanism for storing memories, the team learned. "Instead, successful agers relied more than young rats on a different mechanism for bringing about synaptic change," Gallagher said. "This 'switch' could serve the same purpose storing m...Hostility in women does not affect their long term heart health
...ey component of type A personality, which has been linked to increased risk of poor heart health. The group were then monitored for four years for episodes of illness or hospital admission related to their heart disease. The 'hostility' scores among the two sexes were similar. But men with high scores tende...Physicians slower to incorporate newer heart drug treatments
...o the guidelines measured by CRUSADE is definitely linked to an improvement in outcomes. They reported that over time, mortality risks rose by 3.1 percent at hospitals whose adherence declined, while the mortality risks declined by 37 percent over the same time period among hospitals whose care patterns wer...Neurons generated in the adult brain learn to respond to novel stimuli
... neurons have a unique role in the brain, becoming linked to new smells while the older neurons essentially step out of the way. And since adult-born neurons are continually being generated, there is always a group of new cells waiting to link up with new stimuli," Macklis says. "We're also seeing how the ...Low-carb diet better than low-fat diet at improving metabolic syndrome
... al. argue that the cause of metabolic syndrome is linked to insulin imbalance. Carbohydrates are the main stimulus for insulin, and reducing carbohydrate can be effective at restoring insulin responses. So reducing carbohydrate intake, not fat intake, should be the main aspect of treatment for metabolic sy...Brain scan, cerebrospinal fluid analysis may help predict Alzheimer's disease
...uspect that the creation of amyloid plaques may be linked to breakdowns of the processes that degrade or normally clear A-beta 42 from the brain via the CSF and the bloodstream. However, natural variations occur in CSF A-beta 42 levels in healthy subjects, and the amount this level drops in Alzheimer's pat...Exercise linked to reduced breast cancer risk
...sity of Southern California. Numerous studies have linked physical activity to lower breast cancer risk in w...ng to black women. "A growing body of evidence has linked recreational activity to lowered breast cancer risk, but we really haven't known whether that lowere...Research reveals likely connection between early-life stress and teenage mental health problems
...deeper understanding of the unique vulnerabilities linked to neural changes at puberty and adolescence -- and more specifically, how these adolescent changes interact with earlier vulnerabilities such as major life stressors and social adversity early in life," said Ronald E. Dahl, M.D., the Staunton Profes...UC Davis researchers shed new light on how chemotherapy-induced leukemia develops
...and theSacramento Veterans Administration Hospital linked what appears to be theearliest molecular event involved in the development of therapy-inducedleukemia, the rearrangement of the MLL gene (a gene involved in leukemia),to factors that activate apoptosis, or programmed cell death. "This rearrangement a...Study uncovers potential biomarker for lupus atherosclerosis
... "good" high density lipoprotein (HDL) cholesterol linked to cardiovascular health plays a counterproductive role in people with systemic lupus erythematosus (SLE) and rheumatoid arthritis, promoting atherosclerosis (hardening of the arteries) and heart disease in many of these individuals. The menacing HD...Drinking decaffeinated coffee may be harmful to heart health
...esterol by increasing a specific type of blood fat linked to the metabolic syndrome, hints a new study prese...ol group, that drank no coffee. Some studies have linked coffee drinking to heart disease, but others have suggested that it is not harmful. "The problem wit...New drug target identified for fighting Parkinson's disease
...rast, the alpha-synuclein protein, the first to be linked to Parkinson's disease, is only 140 building blocks long. The parkin protein, linked to more cases of familial Parkinson's disease than any other to date (although LRRK2 is likely to br...Researchers reveals how certain chemicals protect the brain against cell damage
...loid -peptide 42 (A1-42), a compound that has been linked to brain cell death and Alzheimer's disease (AD). ...oxicity, Dor's study shows that this protection is linked to stimulation of receptors EP2 and EP4. This stimulation results in a cascade of events inside brai...High-sugar diet pushing some Latino kids toward type 2 diabetes
...gardless of how fat they are-a finding most likely linked to genetic issues. "Clearly, this is a group that faces a higher risk for metabolic problems," says Jaimie N. Davis, Ph.D., R.D., research associate at the USC Institute for Prevention Research and the study's lead author. "But findings suggest that...Researchers use imaging technique to visualize effects of stress on human brain
...ts of psychological stress in an area of the brain linked to anxiety and depression. This research has important implications for how practitioners treat the numerous long-term health consequences of chronic stress. In the study, which is reported in the Nov.21 online edition of the Proceedings of the Natio...U of M study shows radiation therapy for pelvic cancers increases risk for fractures in older women
...is kept by the National Cancer Institute (NCI) and linked to Medicare, to review the records of 6,428 women. These women were age 65 and older when diagnosed with pelvic malignancies between 1986 through 1999. The researchers' purpose was to determine whether women who undergo pelvic radiation therapy for p...Older women who receive pelvic irradiation for cancer have increased risk for pelvic fracture
...ology, and End Results (SEER) cancer registry data linked to Medicare claims data. A total of 6,428 women aged 65 years and older diagnosed with pelvic malignancies from 1986 through 1999 were included. The researchers found that the cumulative incidence of pelvic fractures was greater in the irradiated gr...Stanford study of sea squirt provides clue to human immune system
... separate, though genetically identical, organism, linked to the others by a common blood vessel. Ringing the tiny petals are even tinier tentacle-like ampullae, the sensing organs that evaluate other sea squirts, determining who's related and who isn't. If two adjacent squirts aren't related, their respect...... They argue that cheap food, particularly meat, is linked to reduced human health and reduced farm animal welfare, both of which are important matters of public interest that are within the professions' respective purviews. The 20th century's drive to lower food prices has resulted in many hidden costs for ...