Dealing deadly cancers a knockout punch
... killing. It is through this second "inflammatory" mechanism that researchers hope Reolysin will bring about lo...se model. The investigators intend to explore the mechanism of this promising synergistic action in further detail in future preclinical work. Another present...Elsevier announces launch of Brain Stimulation
...y. We hope that Brain Stimulation will serve as a mechanism and forum to bring these different disciplines together under one umbrella." Subscribers will be able to access the entire contents of each issue on the journal website, http://brainstimjrnl.com. Plans call for special subscriber-only online conte...JCI table of contents: May 10, 2007
...udy suggests that IL-33/ST2 signaling is a crucial mechanism for protecting the heart and shows that cardiomyocytes and cardiac fibroblasts signal to each other in times of cardiac stress. TITLE: IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system AUTHOR CONTACT:...Study implicates protein as a trigger of advanced prostate cancer recurrence
...ese tumor recurrences. Nupams study nails down the mechanism by which that conversion happens." Among the experiments were those that involved mice that were unable to produce androgen. The animals were implanted with human prostate tumor cells containing an activated form of Ack1. "We found that when prosta...Web-based asthma program dramatically improves disease management for low-income black students
...n include information on asthma medication and its mechanism of action, appropriate techniques for using inhalers and spacers, asthma trigger avoidance and plans to respond to asthma symptoms, said Dr. Joseph. Asthma education for adolescents should also address depression, unresolved anger at having the disea...Animal BiP levels determine amount of recovery sleep needed following prolonged wakefulness
... following sleep deprivation, although the precise mechanism by which this occurs remain to be elucidated. "A...of the unfolded protein response is one protective mechanism against such injury. If protective mechanisms, such as the unfolded protein response, are attenuate...Mayo Clinic research in cardiovascular disease presented at Experimental Biology 2007
...dy from heart disease or stroke. The antioxidant mechanism Dr. Katusic and colleagues identified includes enzymes that protect EPCs from oxidative stress in diseased arteries and veins. Oxidative stress is a consequence of the elevated production of free radicals that are associated with the inability of the...Drama can help educate and motivate, research shows
...y provides evidence that drama can be an effective mechanism to educate and motivate," said Howlett, who was team leader for the research. "The combination of emotion and information had a significant impact on personal activism." The project involved creating and producing a play to educate the Durham, N.C....Dua anti-reflux stent relieves GI upper cancer distress
...rocedures to replace the clogged stents. The exact mechanism that leads to stent clogging is not known. There is a possibility that clogging occurs from contents from the intestines backflowing (refluxing) into the stent. The "Dua Anti-Reflux Valve" was initially developed to reduce reflux of stomach content...New mechanism identified for resistance to targeted lung cancer drugs
...online release, describes a totally new resistance mechanism that may apply to many types of cancer. It also s...alling pathway with MET may be a common resistance mechanism in other therapies that target receptors of the ERBB family, which are used against breast cancer, c...Chronic family turmoil and other problems cause physical changes
...atic load may very well turn out to be the primary mechanism of how risk, stress and other sources of environmental demands get under the skin and into the body," said Evans. In some studies, he noted, high allostatic loads are correlated with a greater incidence of physical, mental and cognitive disorders. Th...Physicians should be able to review performance rates before release
...3. Payers should have a well-defined and distinct mechanism for responding to physician inquiries and requests for reconsideration. Practical time frames must be established to ensure timely resolution of the contested matters and to minimize the delay of public reporting. 4. In submitting a request for re...Researchers discover gene crucial for nerve cell insulation
... myelin. "Our research has uncovered a whole new mechanism for regulating myelin genes," said Dr. Svaren. "Our hope is to exploit this knowledge so that we can adjust the levels of myelin genes such as PMP22 and MPZ, and thereby create an effective treatment for myelin diseases." Understanding the process...Diet and lifestyle -- In the cancer fight, eating well is the best revenge
...ent cancer and promote good health. A novel mechanism for the chemoprotection by 3,3-diindolylmethane (D...ifornia, Los Angeles, have discovered a biological mechanism whereby two compounds in these foods might lower the invasive and metastatic potential of breast and...Mayo Clinic Cancer Center researcher finds mold by-product kills multiple myeloma
...nction as an HDACI; but instead that the cytotoxic mechanism appeared to be at least in part attributable to oxidative stress caused by chaetocin. "Much more research needs to be done," says Jennifer Tibodeau, Mayo post-doctorate fellow and presenter of the study, "but we are hopeful that chaetocin may some ...Consumer nail gun injuries spike
...re the trigger is pulled. This sequential trigger mechanism is designed to prevent rapid, unintentional firing, but it has not been used as much as tools that allow the user to rapidly bounce fire nails. The findings appear in the April 13, 2007, issue of Morbidity and Mortality Weekly Report, published by ...The Clorox company's new personal care product lends a hand
... Available in an easy-to-use spray, this delivery mechanism also helps target places in the hand that can often be missed by traditional sanitizers, such as fingernails, knuckles and spaces between fingers. Cloroxs entry into the professional hand hygiene category exemplifies our commitment to a cleaner an...Mild head injuries increase risk of sleep disorders
...lon said further studies are needed to explain the mechanism behind CRSDs in people with brain injury. ...EVEREST data on use of tolvaptan published in JAMA and featured at ACC
... treatment. "The EVEREST data suggest that the mechanism of action of tolvaptan may represent a new therapeutic strategy that could provide symptomatic improvement for short-term care of hospitalized heart failure patients," said Cesare Orlandi, M.D., vice president of Clinical Development at Otsuka Pharma...Blueberries contain chemical that may help prevent colon cancer
...see AGFD 038 reference below). More studies on the mechanism of action of pterostilbene are needed, the researchers note. Reddy recently demonstrated that certain COX-2 inhibitors, anti-inflammatory drugs that are used for pain and arthritis, were capable of preventing colon cancer in animals. But studies by...