Immune system police learn early and sometimes badly
... find that does not happen, but it's not the major mechanism for generating regulatory cells in the body," Dr. Pacholczyk says. All T cells are made in the bone marrow then move to the thymus as progenitor cells where they differentiate, upregulating surface receptors, which are molecules that detect differe...Compound in dairy products targets diabetes
..., and a decrease in circulating glucose. Also, the mechanism was indeed similar to that of the drugs. "Anti-diabetes drugs act the same way. They mimic the natural activators of the receptors by getting into the cell and interacting with the PPARs to regulate glucose and fat metabolism," says Vanden Heuvel....UCLA study shows altering fatty acid levels in diet may reduce prostate cancer growth rate
...edominantly omega-6 fatty acids. The most likely mechanism for the tumor reductions, according to researchers, was due to an increase of the prostate tumor omega-3 fatty acids DHA and EPA and a lowering of the omega-6 acid known as arachidonic acid. These three fatty acids compete to be converted by cycloox...Kentucky researcher receives prestigious Lew R. Wasserman Award
...Dr. Ambati is focused on dissecting the underlying mechanism responsible for AMD with a goal of using this knowledge to develop treatment strategies to prevent the onset of significant visual loss," said Pearson. "With the aging of baby boomers, AMD promises to become an even more common cause for vision l...MIT researchers watch brain in action
...he said, "we suspect that this molecular filtering mechanism may also be applicable to other information processing systems in the brain." Although baby animals are born with a handful of neurons tuned to respond to edges of light at specific orientations, the ability to detect these orientations improves w...Drug triggers body's mechanism to reverse aging effect on memory process
...ade to enhance memory appears to trigger a natural mechanism in the brain that fully reverses age-related memor...ontinue to reverse the effects of aging on a brain mechanism thought to underlie learning and memory even after they are no longer in the body. They do so by boo...Inhaled nitric oxide reduces lung disease in premature babies
... its value for preterm infants was uncertain. "The mechanism by which nitric oxide affects the lungs is not fully understood," said Dr. Ballard, "but animal studies and pilot studies in infants previously suggested that nitric oxide restores normal growth and development in very immature lungs." The trial wa...Clinical guidelines for recalled pacemakers and implantable cardioverter-defibrillators developed
...nts with implantable devices and having a rational mechanism to approach these patients is critical to patient care," said Ellenbogen. Ellenbogen and Amin collaborated with Mark Wood, M.D., VCU professor of internal medicine, and David Matchar, M.D., professor of medicine at Duke University. According to ...W.M. Keck Foundation announces 2006 class of Distinguished Young Scholars in Medical Research
...al Medicine, Yale University - Dr. Bogan studies a mechanism through which insulin triggers cells to take up gl...ocor and Lipitor. His work has revealed an elegant mechanism by which this enzyme is rapidly destroyed when sterols build up in liver cells. His research may she...Matrilin-3 gene discovered to prevent onset of osteoarthritis
...a. "In the long term, it helps us understand the mechanism of human osteoarthritis development. Very few mole...iously examined," the authors write. "However, the mechanism of the association between increased bone density and joint degeneration is not known. Our data show...For-profit research ethics committees: How are they performing?
An important mechanism for protecting human research participants is the prior approval of a study by a research ethics board, known in the United States as an institutional review board, or IRB. Traditionally, IRBs have been run by volunteer committees of scientists and c...Light to moderate drinking reduces risk of cardiac events, death
...n. Therefore, researchers have suspected that the mechanism linking alcohol to reduced risk of cardiovascular disease may be related to inflammation. Cinzia Maraldi, M.D., of the Institute on Aging, University of Florida, Gainesville, and colleagues investigated the relationship between alcohol, death and c...Sawing the ZZZZZs: getting old needn't keep you awake, Saint Louis University geriatricians say
... a new group of medicines that work on a different mechanism are promising, she adds. "There are several newer sleep medications on the market that potentially could better assist with sleep and have fewer side effects," Dr. Gammack says. "Given the prevalence of insomnia in the elderly population and the...Rutgers-Newark researcher discovers new motor protein mechanism linked to heart disease and strokes
...orkers reveal that they have identified a possible mechanism used by an important motor protein which acts as a... Spectroscopy technology, Kalodimos identified the mechanism of function of motor protein SecA, which uses chemical energy and converts it into mechanical energy...Scientists discover why cornea is transparent and free of blood vessels, allowing vision
...y to suppression of blood vessels and that the key mechanism is expression of VEGFR-3. "The results from this series of tests, confirmed our belief that the presence of VEGFR-3 is the major factor in preventing blood vessel formation in the cornea," says Dana, who says that the discovery will have a far reac...Hypertension provokes cardiac insufficiency
...Sebastin. The article describes a newly-discovered mechanism through which the hearts of persons with hypertens...signed a blood analysis which detects whether this mechanism is damaging the heart, which in turn makes possible the use of therapeutic techniques to block the m...Taking the wrinkles out of motoneuronal disease
..."The aim of our lab is to understand the molecular mechanism underlying neuronal communication. The legacy of millions of years of evolution and competition between venomous species has resulted in deadly neurotoxins capable of blocking neuronal communication. I am using our knowledge of the mode of action of ...Studies indicate medication can be an effective therapy for smoking cessation
...ts a third class of drug with probably a different mechanism of action than either nicotine replacement therapy or bupropion. On the other hand, varenicline definitely is not a panacea for smoking cessation. Many participants in these trials experienced adverse events, stopped taking their study medication bef...JCI table of contents: July 3, 2006
...ry. However, there is a growing consensus that the mechanism of any potential therapeutic benefit is unknown an...o human ARVC. The study provides a novel molecular mechanism for how this disease develops and an animal model of human ARVC for future study. In an accompanying...Study details why listeriosis rates are 20-fold higher during pregnancy
...ult from these infections may be a natural defense mechanism to dispel this source of infection." The study will be posted on June 30 in the June issue of the online journal PLoS Pathogens. Listeriosis is a foodborne illness caused by Listeria monocytogenes. Every year in the United States, about 2,500 people ...