Diabetics who control blood sugar today are more likely to have healthy feet and nerves tomorrow
...exciting finding that adds credence to the idea of metabolic memory, or the concept that there can be a durable effect from early and sustained efforts to keep blood sugar low," says senior author Eva Feldman, M.D., Ph.D., the DeJong Professor of Neurology at the University of Michigan Medical School and direc...Research shows fat fuels inflammation killer
... the inner layer of the artery vessel wall, in the metabolic processes leading to obesity and cardiovascular disease". "This observation opens opportunities to develop new treatments that deal directly with inflammation either through diet or drugs"....Declines in exercise capacity may be due to lack of training, not just age
... the bad news conveyed to us by Woo et al. is that metabolic debts associated with the performance of dynamic exercise increase with aging. These debts, paid during recovery from exercise are likely attributable to an inability of the older body to adapt to the energy requirements of exercise," they wrote. But...Neural transplants provide persistent benefit in patients with Huntington's disease
...allel with long-lasting focal improvement in brain metabolic activity. Progression of the disease led to heterogeneous secondary clinical alterations and changes of cerebral metabolism. Whereas neuronal transplantation is not a permanent cure for Huntington's disease, it does provide a period of improvement an...New, expensive, widely-used drugs continue to cause liver problems, says Jefferson liver specialist
...rugs." Studies need to be done to uncover specific metabolic pathways involved in drug-caused liver injuries, Dr. Navarro adds. "Why do certain people develop injuries while others don't? Some may be susceptible because of a genetic constitution that makes them react to a drug. The pharmaceutical industry want...UCSF research pinpoints brain molecule's role in developing addiction
... situations, orexin is released during 'heightened metabolic states,' such as when an animal is hungry. But when the animal is addicted to drugs of abuse, this motivational neural pathway is enhanced, resulting in increased orexin release onto dopamine neurons of the VTA." The discovery of orexin's molecular ...A bulging midriff roughly doubles women's chances of gallstone surgery
...vious research has also linked gallstones with the metabolic syndrome, a feature of which is excess abdominal fat....Metabolic acidosis associated with an increased mortality rate
Critically ill patients with metabolic acidosis are twice as likely to die as patients who do not have metabolic acidosis. A study published today in the journal Critical Care shows that the mortality rate among p...Unique vascular dysfunction in women's heart disease described in major journal supplement
...is not obesity alone. Instead, it appears that the metabolic alterations associated with obesity are key factor...er risk of cardiac events than those with a normal metabolic status. The metabolic syndrome includes insulin resistance, unhealthy cholesterol and/or triglycerid...Obesity may be factor in accelerated type I diabetes in some patients
...on and can no longer compensate for the additional metabolic demands associated with higher body mass index." Body mass index (BMI) is computed from weight and height; a BMI over 30 indicates obesity. The body uses insulin in metabolizing carbohydrates and in regulating glucose (blood sugar) levels in the body...Elsevier to publish Journal of Clinical Densitometry
...monitoring of patients with osteoporosis and other metabolic bone diseases. It provides a unique, cross-disciplinary perspective addressing the concerns of all health professionals involved in the clinical use of dual energy x-ray absorptiometry and related techniques. The journal's audience includes physici...OHSU research reveals the complexities of obesity/cortisol interactions
...OMC in the brain did not show improvement in their metabolic state. The treatments actually led to an acceleration in weight gain and development of diabetes," explained Low. "Importantly, the identical treatments had no discernable effect in control mice with normal POMC levels in the brain. This research dem...Increased role for PET imaging could improve cancer care
...spatial information obtained in a CT scan with the metabolic information from PET. There also are plans to purchase a second PET-CT scanner....International Journal of Epidemiology obesity special
...d adolescents has already resulted in long-lasting metabolic and vascular abnormalities, write Dr Debbie Lawlor (Bristol University) and Dr Nish Chaturvedi (Imperial College, London) . They argue that targeting the prevention of obesity during key periods of a child's development could be the way to reduce sub...Researchers study multi-purpose drug
...ator for STRADIVARIUS. "These risk factors, called metabolic syndrome when combined in one person, feed off eac...ronary artery disease." Specifically, people with metabolic syndrome have at least three of the following risk factors: abdominal obesity, high blood pressure, ...Pollution puts fat rats at heart attack risk
...cy." The growing pandemic of obesity, pre-diabetic metabolic syndrome and Type 2 diabetes is creating a new generation of cardiovascular dysfunction--such as heart disease or stroke--that is increasingly influenced by the external environment. Russell's research team--including the U of A's Dr. Spencer Proctor...Race/ethnicity predict lipids, heart-disease risk in HIV-1 patients on protease inhibitors
...is the largest pharmacogenetic analysis to date of metabolic changes associated with antiretroviral drugs and t...ent classes. The team emphasized that, despite the metabolic problems involved with protease inhibitors and other antiretroviral drugs, the benefits of the medic...Ethnic differences in response to HIV medicines
...ighly active antiretroviral therapy causes various metabolic complications, including the development of dyslip... increased risk of antiretroviral therapy -related metabolic complications will improve the selection of appropriate antiretroviral regimens and preventive cardi...Metabolic syndrome identified as risk factor for kidney-pancreas transplant patients
...um in Scottsdale, Ariz. The researchers found that metabolic syndrome, a cluster of symptoms that increase the ...d sugar and cholesterol the variables that define metabolic syndrome." In kidney and pancreas transplantation, advances in immunosuppressive drug therapy have s......amined the association between work stress and the metabolic syndrome (a cluster of factors that increases the ...occasions between 1985 and 1999. Components of the metabolic syndrome, such as obesity, high blood pressure, and high cholesterol levels, were measured between 1...