Interaction between lymph and liver cells may affect immune response
...ry of TEHLI is the first demonstration by electron microscopy of the interaction between nave T cells and liver cells in a living organism, which shows that the liver is an exception to the rule that T cells need to be activated by professional APCs in order to cross the endothelial barrier, and that hepatocyte...Optical technique provides improved 'virtual biopsies' of internal surfaces
...t's senior author. "With OFDI, we can now perform microscopy throughout very large volumes of tissue without missing any locations." While OCT can examine surfaces one point at a time, OFDI is able to look at over 1,000 points simultaneously by using a new type of laser developed at MGH-Wellman. Inside the...Innovative movies show real-time immune-cell activity within tumors
(PHILADELPHIA) Using advanced new microscopy techniques in concert with sophisticated transgenic technologies, scientists at The Wistar Institute have for the first time created three-dimensional, time-lapse movies showing immune cells targeting cancer cells in live tumor tissues. In recorded e...Bottleneck in blood supply makes brain vulnerable to strokes
... fluorescence microscopy. Two-photon fluorescence microscopy is a powerful imaging tool that uses brief (less than one-trillionth of a second) laser pulses to peer below the surface of the brain. In contrast to a previous study, in which the team showed there was very little disruption in blood flow when a ...Novel computed imaging technique uses blurry images to enhance view
... computational image-forming technique for optical microscopy that can produce crisp, three-dimensional images f...hetic Aperture Microscopy, ISAM can do for optical microscopy what magnetic resonance imaging did for nuclear magnetic resonance, and what computed tomography did...McMaster University researchers discover zip codes for protein
...ers new Biophotonics Facility and the use of laser microscopy in living brain cells. It will also use the McMaster High Throughput Screening Facility to screen for new drugs that can affect how huntingtin is signalled. "This class of small molecule drugs we are now working with has been proven recently to......, INSERM and CNRS researchers have used two-photon microscopy to demonstrate, for the first time in vivo and real-time, how T lymphocytes infiltrate a solid tumour in order to fight it. These "defenders" methodically encircle the enemy positions and "patrol" until they meet a tumour cell, which they have previ...Diagnostic tests for malaria underused in Zambia
...of Oxford, assessed the association between use of microscopy and RDT and the prescription of antimalarials in Zambia. The researchers conducted a survey, carried out between March and May 2006, of 104 government and mission health facilities in four districts in Zambia. At each facility, data were collected d...Certain combination therapy found more effective for treating malaria in African children
...dering the availability of resources such as light microscopy and rapid diagnostic tests, as well as increasing funding through such programs as the Global Fund and President's Malaria Initiative, it seems that improved malaria management, with evaluation and diagnosis-based treatment for all febrile children, ......hy cells. Further verification comes from electron microscopy experiments. The high contrast provided by the gold nanoparticles allows the determination of the specific sites in the cell machinery where the nanoparticles are attached. Shi pointed out that it should be possible to design dendrimer nanoparticles ...'Cars' imaging reveals clues to myelin damage
... Cheng said. The research demonstrates that CARS microscopy is a valuable research tool and could become a future clinical method to diagnose multiple sclerosis and detect damage to the spinal cord from accident trauma, which also causes the myelin to degrade, he said. Research findings are detailed in a pa...Indiana University Imaging Center receives $6M grant for kidney research
... that has beendeveloped at IU using advanced light microscopy systems to conductresearch in kidneys and other or...the IndianaCenter for Biological Microscopy. The microscopy systems in conjunction with software designed at thecenter use fluorescent molecules to produce deta...