Exercise may lead to improvement in patients with Parkinson's
...-term effect on the injured brain, identifying the molecular links between exercise and the brain, and to better understand the molecular mechanisms within neurons that lead to these changes....Elsevier launches Molecular Oncology
... on the advances in the rapidly expanding field of molecular oncology. The first issue will appear online today and be available in print in the first week of June 2007. Prof. Julio E.Celis, Scientific Director of the Institute of Cancer Biology at the Danish Cancer Society in Copenhagen, will be the foundin...Students devise oral quick-dissolve strips for rotavirus vaccine
...Mao. Truong earned a doctorate in pharmacology and molecular science from the Johns Hopkins School of Medicine and knew of Maos expertise in biomaterials. Mao, an assistant professor of materials science and engineering in the university's Whiting School of Engineering, described the vaccine challenge to one o...Glucosamine-like supplement inhibits multiple sclerosis, type 1 diabetes
...stant professor of neurology, and microbiology and molecular genetics. Most importantly, we understand how this sugar-based supplement inhibits the cells that attack the body, making metabolic therapy a rational approach to prevent or treat these debilitating diseases. The UC Irvine study defines how metabol...Elsevier announces launch of Brain Stimulation
...f this rapidly evolving field, from the most basic molecular research, to innovative technology and surgical techniques, to practical clinical studies. The editorial focus will encompass all technologies and methods using any type of stimulationelectrical, magnetic, ultrasound, or pharmacological, and otherst...JCI table of contents: May 10, 2007
...ation, these same authors provide insight into the molecular mechanisms of how TACI mutations cause CVID. TACI is a cell surface receptor and is mainly expressed on B cells. The authors examined mice carrying a C76R TACI mutation (the equivalent of the human C104R mutation) and found that mutated TACI is una...New therapeutic targets for neurodegenerative diseases
...edicine and Odontology is the investigation of the molecular and cellular bases of neurodegenerative illnesses ...e animals. In this way it can be determined if the molecular targets discovered experimentally are relevant or not to the neurodegenerative processes and, if the...Scientists equip bacteria with custom chemo-navigational system
...ormation-processing capabilities to powerful, tiny molecular motors that propel the cells forward. Researchers have long envisioned reprogramming bacteria so that microbes capable of synthesizing an anti-cancer drug, for instance, can be used to target diseased cells while sparing healthy cells of side effec...Uveal melanoma patients at higher risk for colon cancer
...eal melanomas may provide further insight into the molecular pathogenesis of this cancer. ...TWAS, illycaff announce Trieste Science Prize winners 2007
...uato, Mexico, helped to pioneer the field of plant molecular biology and genetic engineering. Plant transformat...maize and papaya. In addition, his analysis of the molecular mechanisms of toxins, produced by the disease-causing bacterium Pseudomonas syringae pv phaseolicola...Animal BiP levels determine amount of recovery sleep needed following prolonged wakefulness
...overed that there are substantial increases in the molecular chaperone BiP in Drosophila head and brain after modest periods of sleep deprivation. These increases decline progressively during recovery sleep. However, even after 24 hours following sleep deprivation, there is still a small but significant incr...Researchers urge caution in using ESAs for cancer-related anemia
...ote cancer growth. Several studies have identified molecular receptors of erythropoietin in the endothelial cells lining blood vessels and possibly in tumor cells as well. Because of their genetically modified characteristics, ESAs may have stronger effects on these receptors than natural erythropoietin does. ...Jefferson pharmacologist says biomarker discovery bodes well for better cancer diagnostics
...sion of cancer, and which identifies new potential molecular targets that we can direct therapeutics against." Yet, he cautions, "There is a great distance between biomarker discovery and application in the doctors office." Validating such biomarkers require "well designed, prospective, multicenter clinical...OCT1 required for therapeutic effects of diabetes drug Metformin
...rs, only recently have studies begun to reveal the molecular events responsible for its therapeutic effects. Notably, these studies have shown that metformin acts by phosphorylating the enzyme AMPK, the cellular "energy-sensor", leading to a variety of cellular responses important in diabetic therapy. A set ...JCI table of contents: May 1, 2007
...rs, only recently have studies begun to reveal the molecular events responsible for its therapeutic effects. No...10 ACCOMPANYING COMMENTARY TITLE: Cellular and molecular basis of wound healing in diabetes AUTHOR CONTACT: Harold Brem Columbia University, New York, New...'Wrapping' Gleevec fights drug-resistant cancer
...in of cancer when the drug wraps the target with a molecular bandage that seals out water from a critical area....variant WBZ-7. The wrapping prototype is a kind of molecular bandage that's designed to keep water molecules from getting near the "active site" of KIT the part...Mayo Clinic research in cardiovascular disease presented at Experimental Biology 2007
...indings will lead to improved understanding of the molecular design of EPCs, says Dr. Katusic, a specialist in ...nd damage major organs, such as the heart. But the molecular mechanisms that kick-start this process, called pathologic calcification, havent been explained. ...Alzheimer's, Parkinson's, type 2 diabetes similar at molecular level
...enerative diseases are more closely related at the molecular level than scientists realized, a team reports thi... design," said David Eisenberg, a UCLA chemist and molecular biologist who is part of the research team. The researchers studied the harmful rope-like structur...New animal study may explain why alcohol consumption increases breast cancer risk
...derstood. The definitive biological effects and molecular mechanisms of EtOH on progression and malignancy of breast cancer have not been investigated using a mammalian breast cancer model that mimics the human disease. Scientists have suggested that the possible mechanisms involved include the agitation of...Correlation between bile duct obstruction and ductal cancer found
...ogression of the cancer and that could become good molecular targets for drug therapy. Second, they establis...hat can be used to rapidly test and evaluate novel molecular treatment strategies. Such strategies are badly needed for this understudied cancer, adds Dr. Siri...