Tag: "molecular" at medical news
Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
...ted cells were stimulated with IL-1, a sequence of molecular
events occurred that resulted in production of the bone-destructive molecules. But the scientists found that pre-incubation with EGCG was capable of blocking the production of these molecules in a dose-dependent manner. Furthermore, EGCG also inhibit...
Green tea compound may be a therapy for people with rheumatoid arthritis
...ted cells were stimulated with IL-1, a sequence of molecular
events occurred that resulted in production of the bone-destructive molecules. But the scientists found that pre-incubation with EGCG was capable of inhibiting the production of these molecules. EGCG also inhibited the production of prostaglandin E2,...
XDx presents success with AlloMap molecular expression testing to international transplant community
San Francisco, CA, April 26th, 2007 -- XDx, a molecular
diagnostics company, today announced its AlloMap molecular
expression test will be the subject of presentations and discussions at the 27th Annual Meeting and ...
Water flows like molasses on the nanoscale
... such an increase in viscosity. The results of the molecular
dynamics simulations support these findings, showing a dramatically decreased mobility for sub-nanometer thick water films under hydrophilic confinement. "Water is a wonderful lubricant," said Riedo, "but it flows too easily for many applications....
SNM's 54th Annual Meeting speakers address state of molecular imaging/nuclear medicine technologies
...STON, Va. -- Internationally recognized experts in molecular
imaging and nuclear medicine are on hand for SNMs ...shington, D.C. SNM, the worlds largest society for molecular
imaging and nuclear medicine professionals, annually showcases research that promises to revolutioni...
...tle alteration, which has minimal influence on the molecular
shape, can also be predicted quantitatively. The human nose was indeed fooled. Tacke says, "All four of the synthesized compounds had the typical floral aldehydic lily-of-the-valley fragrance, but didn't smell completely identical." However, near the...
Study reports changing to a low-fat diet can induce stress
...es, "Our behavioral, physiologic, biochemical, and molecular
analyses support the hypothesis that preferred diets act as natural rewards and that withdrawal from such a diet can produce a heightened emotional state." Once deprived of their preferred diet, mice would overcome their natural aversion to bright en...
Research could lead to treatment for Alzheimer's disease
...tment in the chemistry and medicinal chemistry and molecular
pharmacology departments. "Interdisciplinary res... how the inhibitor worked, the interactions of the molecular
bonds and what properties were most important," Ghosh said. "This allowed us to quickly build inhibi...
Study links breast cancer risk to epigenetic changes related to race, smoking and birth size
...called DNA methylation, whereby DNA is tagged by a molecular
"methyl" fragment, which alters activation of the genes. In this instance, the researchers looked at global hypomethylation aberrant methylation throughout the entirety of a persons DNA. The researchers found differences in global DNA hypomethy...
Diet and lifestyle -- In the cancer fight, eating well is the best revenge
... treatments," said Erin Hsu, a graduate student in molecular
toxicology. "But we need to test that notion in animals before we can be more definitive." Both DIM and genistein are already being developed for use as a preventive and a chemotherapy treatment for breast cancer, although more extensive toxicologi...
Fragile X, Down syndromes linked to faulty brain communication
..., said Daniel Madison, PhD, associate professor of molecular
and cellular physiology. "It's as if you had every light in your house wired to just one or two switches, rather than having many switches that can be flipped on or off in complex combinations to control the lighting in one room," he said. Madison ...
Slick and springy: Brown research reveals protein's role in joints
... structures inside synovial fluid. To study this molecular
interaction, researchers put microscopic, fluorescent beads into two samples of synovial fluid. One sample was normal. The other came from a patient whose body doesn't produce lubricin. This rare condition, called CACP syndrome, causes premature join...
Nanoparticles can track cells deep within living organisms
...hough we reported the first use of perfluorocarbon molecular
imaging for detection of certain pathologies a few...ging approach already is becoming more popular for molecular
imaging of various cell and tissue types." Next the research group will evaluate how nanoparticle-...
Study describes action of estrogen in protecting bone
...e incidence of bone fractures. Our research at the molecular
and cellular level suggests that the underlying basis of this protective effect of estrogens involves the prevention of apoptosis in osteoblasts and that the key event in this prevention is the inhibition of caspase-3 activity." Bradford is an associ...
Biologists learn structure of enzyme needed to power 'molecular motor'
... to ADP. This release of energy is used to run the molecular
motor in the T4 virus. The virus consists of a head and tail portion. The DNA-packaging motor is located in the same place where the tail eventually connects to the head. The motor falls off after the packaging step is completed, allowing the tail ...
Major discovery raises prospect of better patient care by improving platelet life span
...life span. We now know the identity of the precise molecular
switch responsible. The team is now actively pursuing a drug development program aimed at manipulating this switch in order to prolong the life span of blood bank platelets, increasing their availability to patients receiving cancer treatment and oth...
Simmer to receive research in Biological Mineralization Award
...particular, for his investigations on the cell and molecular
biology of tooth enamel formation. Early in his career, in studies on the proteins guiding tooth enamel development and maturation, he made significant observations on the alternative splicing of amelogenin RNA transcripts, and he expressed and chara...
Researchers hot on the trail of brain cell degeneration
...earch Fellow Michael Courtney has identified a new molecular
pathway in neurons. The pathway is a factor in the...gies for neurodegenerative diseases". Targeting molecular
signals How neurons actually die has been unclear. It is likely that it is associated with a vari...
A closer look inside our lungs -- Penn researchers develop 2 novel imaging techniques
...ormal or abnormal. This is a whole new approach to molecular
imaging. For the first time, we can now follow the...o pinpoint the location of disease. It's real-time molecular
imaging. This is revolutionary to MRI technology." Penn is one of only a few sites in the world, ...
Study questions 'cancer stem cell' hypothesis in breast cancer
...ed "cancer stem cells" were driven by an activated molecular
pathway that makes them resemble normal stem cells. Women whose breast tumors are largely made up of these "stem-like" cells are at higher risk of recurrences. On the positive side, the abnormal activated pathway in these cells, known as the TGF-B...
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