Tag: "molecular" at medical news
Molecular differences between early and advanced melanomas could provide new drug targets
...rs, scientists have found. Understanding this key molecular
difference between radial melanomas that spread on the surface of the skin and melanomas that grow vertically and invasively could provide new targets for the development of drugs to treat individuals with advanced stage melanomas. Radial melanoma...
NIH names Clinical Trial Units for the Microbicide Trials Network
...trics, gynecology and reproductive sciences and of molecular
genetics and biochemistry at the University of Pittsburgh School of Medicine and director of reproductive infectious disease research at the Magee-Womens Research Institute. The MTN brings together international investigators and community partners...
Metacognition: Faced with a test, rats can check their knowledge first
...ide opportunities to study the neuroanatomical and molecular
mechanisms that underlie metacognition. ...
Obesity and environmental chemicals -- New research probes potential link
...agliaferro and Deena Small, assistant professor of molecular
biology and biochemistry. The trio received fundin...describes as critical windows for exposure. At the molecular
level, Small will examine what PBDEs are doing to stem cell populations within the adipose tissue an...
New research may overturn conventional wisdom on drug-resistant tuberculosis
...d coworkers in Shanghai, China and elsewhere, used molecular
genetics and drug susceptibility testing to investigate patients with TB who were treated in Shanghai hospitals during 1999-2004. They focused on 38 patients from whom samples were available before and during treatment. The researchers found that the...
New class of targeted cancer drugs shows promise in slowing progression of recurrent prostate cancer
...ncer, a new Cedars-Sinai study shows. The drug, a molecular
targeted compound called pertuzumab, works by binding to and inhibiting the function of HER2 receptors, interrupting a key pathway that leads to cancer growth. The study, published in the February 20 issue of the Journal of Clinical Oncology, i...
Picture this: FSU professor's research could lead to vastly improved medical imaging
...d Technology that uncovered unique properties in a molecular
magnet properties that could significantly increa...ecule made up of eight iron ions that form a tight molecular
bond," Dalal said. "It has a powerful magnetic field, which is obviously important in generating a v...
...sk-shaped monomers equipped with a ring of special molecular
"hooks" that can be activated by UV light. When a solution containing these disks is irradiated, the hooks grab on to each other, linking the disks into little, two-dimensional "patches" that in turn hook on to other patches. Once they reach a certai...
Common anesthetic may induce cell death, generation of Alzheimer's-associated protein
...o isoflurane. Overall, the study's results define molecular
pathways by which isoflurane induces deposition of A-beta, both directly and via caspase activation, and by which A-beta deposits lead to further caspase activation and apoptosis. "Even though our findings and those from other studies suggest that ...
ACS News Service Weekly PressPac -- January 31, 2007
... up a cell's skeleton and act as superhighways for molecular
transport. Zhang and colleagues point out that existing superlenses, including one developed by his group in 2005, can form an image at the near field. The new FSL image more distant objects by capturing and amplifying "evanescent" light waves that...
Using nanomagnets to enhance medical imaging
... reached conflicting conclusions on the utility of molecular
nanomagnets for MRI, but without accounting for co...ties that are difficult to control. By comparison, molecular
nanomagnets can be designed to have consistent properties and high contrast. In addition, they might...
New compound shows promise in halting HIV spread
...ies on a larger scale. Theyll be investigating the molecular
mechanisms of 2-5AN6B as a potential weapon against HIV, and continue work on a new therapeutic approach involving gene therapy for the treatment of HIV infection. ...
Garlic hope in infection fight
... experts in child health, respiratory medicine and molecular
microbiology with clinicians at the Nottingham University Hospitals NHS Trust. Cystic fibrosis is an inherited condition that affects around 7,000 people in the UK, half of whom are children. The disease causes difficulties in digesting food and ch...
Mayo Clinic research shows young people who died suddenly and inexplicably had genetic heart defects
...d form of postmortem genetic testing -- known as a molecular
autopsy -- they found that more than one-third die...g what caused the premature death. Mayo Clinic's molecular
autopsy is a detailed examination at a molecular
level of heart function. Molecular autopsies can he...
Embargoed Jan./Feb. Annals of Family Medicine tip sheet
... The management guideline supports the use of low molecular
weight heparin for patients with deep vein thrombosis in the outpatient setting, when appropriate support services are in place. Each guideline contains several recommendations based on current evidence to clinicians to aid in the diagnosis and trea...
McMaster University researchers discover zip codes for protein
...Associate professor Ray Truants lab has discovered molecular
zip codes or protein sequences in the huntingtin protein that dictate where it goes to within a brain cell. "We have shown that the mutant huntingtin protein is mis-localized in brain cells in Huntingtons Disease, because it is being improperly si...
UIC receives grant to find new drugs for bipolar disorder
...ncluding weight gain." Efforts to understand the molecular
target for lithium have shown that compounds that inhibit the enzyme glycogen synthase kinase-3 may mimic the therapeutic action of the mood stabilizers, Kozikowski said, and might point the way to the design of improved drugs for treating patients w...
Common blood pressure drug treats muscular dystrophy in mice
...gy comes from understanding the basic science, the molecular
underpinnings of the disease. Second, the treatment has worked exceptionally well in animal models. Third, we are not dealing with a mysterious compound that was simply pulled off the shelf - losartan has already been proven safe," says Dietz. "Fu...
New angiogenesis inhibitor has promise for treating deadly brain tumor
...oid treatment. Analysis of potential biomarkers molecular
and cellular factors that can be measured in the blood identified several that may indicate when the period of vascular normalization is ending or which patients' tumors are most likely to become resistant to AZD2171 treatment. These findings sugge...
Exploring the molecular origin of blood clot flexibility
...hown that a well-known protein structure acts as a molecular
spring, explaining one way that clots may stretch ...ent research extends those earlier findings to the molecular
level, suggesting a way that individual fibers flex - by the unraveling of the three, tightly twiste...
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