Low-carb diets' effects linked to rise in newly identified 'starvation hormone'
...tain, pharmacological studies of mice and diabetic monkeys had previously shown promise for FGF21 therapy as a means to lower blood sugar and lipids and stave off weight gain. Mammals survive periods of nutrient deprivation by shifting from carbohydrates to so-called ketone bodies as a primary fuel source....Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys
...according to the results of tests carried out with monkeys by the Navarra University Hospital, led by Dr Mara... area of the brain, the improvement in movement in monkeys with Parkinson's and which had received transplants was demonstrated to last for at least a year. ...Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
...hey reached adulthood. Researchers observed as the monkeys navigated an open area to locate highly valued foo...rks) on baited goal boxes so they could assess the monkeys memory and use of spatial arrangement and markers. "When both spatial and marker cues were availa...Transplanting organs from animals to humans -- what are the barriers?
...ng cells (islets) from pigs were transplanted into monkeys with diabetes and this led to complete reversal of diabetes for over 100 days. But such research is still a long way off from being relevant to humans, says the author. For example, in the pig-to-monkey studies, very large doses of drugs called "imm...New study demonstrates nicotine's role in smoking behavior
... Dr. Steven R Goldberg (NIH) tested naive squirrel monkeys for their motivation to take nicotine. In these tests, the animals could voluntarily self-administer nicotine by pressing on a lever. Receiving nicotine was associated with distinctive environmental cues, to mimic the situation associated with tobac...Preclinical results of Geovax's AIDS vaccines demonstrate potential to protect against disease
... utilizing GeoVax's vaccines. In this trial, two monkeys were infected with the SIV AIDS virus and then pla... therapy had temporarily reduced virus levels, the monkeys were vaccinated with the SIV version of GeoVax's DNA/MVA vaccines. Six weeks after vaccination, dru...Brain cell and face perception research wins Eppendorf/Science Prize
...ains perceive individual faces. Her experiments in monkeys have shown that their brains have specific regions...ctober in Atlanta, Georgia. Tsao's experiments in monkeys have shown that the brain has specific regions devoted to recognizing faces. She describes her inves...Mirrors in the mind: New studies elucidate how the brain reflects onto itself the actions of others
...s, so-called auditory mirror neurons activate when monkeys perform certain actions and when they hear the same actions being performed. In the new work, the researchers report new evidence for an auditory mirror system existing in humans as well. When subjects were presented with sounds corresponding to mo...Tulane researcher reports on origin of deadly fever outbreak
...ilities in 1967 after outbreaks traced to infected monkeys imported from Uganda. Only a few sporadic cases were reported until the 19982000 outbreak in the Democratic Republic of the Congo. The team recorded a fatality rate of 83 percent for that outbreak. Young male miners comprised 52 percent of the cases......n National Primate Research Center, has found that monkeys prevented from forming a strong bond with their mothers as infants go on to be less social, less likely to investigate new situations and more prone to anxiety as adults. Shonkoff said the animal work has an important parallel in human developmen...Trans fat leads to weight gain even on same total calories, animal study shows
...ashington, D.C. She said that over six years, male monkeys fed a western-style diet that contains trans fat h...body weight, compared to a 1.8 percent increase in monkeys that ate monounsaturated fats, such as olive oil. All that extra weight went to the abdomen, and som...Monkeys vaccinated against SIV survive longer after infection
...rer, Ph.D., of the VRC. The researchers found that monkeys vaccinated against simian immunodeficiency virus (...elative of HIV that causes an AIDS-like disease in monkeys -- and then exposed to the virus survived significantly longer than unvaccinated animals exposed to ...OHSU researchers discover possible HIV therapy in an animal study
... "What we were able to discover using SIV-infected monkeys was that a certain naturally occurring protein called interleukin-15 (IL-15) caused a dramatic restoration of tissue CD4+ T cells when given in conjunction with antiretroviral drugs." Antiretroviral drugs are currently given to HIV-positive patients ...New sleep medication shows less potential to foster abuse and dependence
...d drug side effects, capitalizing on the fact that monkeys just like humans -- can be trained to recognize t...class." In one experiment, the researchers trained monkeys to press a lever only when given a benzodiazepine called midazolam (Versed). Then the team gave the...OHSU primate center research suggests multiple 'body clocks'
...s studied adrenal gland function in rhesus macaque monkeys which is very similar to human adrenal gland funct...s measured gene expression in the adrenal gland of monkeys during a 24-hour period (six times a day, four-hour intervals). In analyzing this information, resea...Vaccine given post-exposure protects monkeys against deadly Marburg virus
...rg virus helped all of them survive. Three control monkeys not protected with the vaccine all died within two weeks. This result demonstrates that it may be possible to use rVSV vaccines to treat Marburg and similar viruses, such as Ebola, after infection. Studies are now in progress to determine how late af...Vaccine could be effective after exposure to Marburg virus
...rus surface protein. The team infected five rhesus monkeys with the Marburg virus and 20-30 minutes later injected them with the vaccine. Another three monkeys infected with Marburg virus acted as controls and received a vaccine without the Marburg protein. Th...JCI table of contents, April 6, 2006
...elated, FDA-approved drug, cysteamine, to mice and monkeys with HD. Together these studies reveal that cystamine and cysteamine raise BDNF in an HSJ1b-dependent manner and may be useful as potential treatments for HD. TITLE: Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HS...Depressed monkeys may help scientists understand human depression
WINSTON-SALEM, N.C. Depressed monkeys not only look and act like depressed people, but t...ssion treatments. "Brain scans of depressed female monkeys revealed the same underlying neurobiological changes that are found in the brains of depressed peopl......, enables such rusting. Dr. Snodderly's studies of monkeys raised on a synthetic diet lacking components of the pigment lutein and zeaxanthin showed they also lacked the pigment until the components were added to the diet. "The retina was able to take it up, even though it had never seen it before," he sa...