Drug treatment improves learning in mice with Down syndrome symptoms, Stanford/Packard study shows
...ation," said Garner. A key component of enduring neural change associated with memory is known as long-term potentiation. In general terms, once a threshold of activating signals has been achieved, a neuron becomes permanently more sensitive to excitation. Although long-term potentiation has been shown to...Mimicking how the brain recognizes street scenes
...ons process input and output stimuli according to neural recordings in physiological labs. Like the brain, the model alternates several times between computations that help build an object representation that is increasingly invariant to changes in appearances of an object in the visual field and computati...Common anesthetic may induce cell death, generation of Alzheimer's-associated protein
...hat applying the anesthetic isoflurane to cultured neural cells can lead to generation of amyloid-beta prote...s first found that applying isoflurane to cultured neural cells increased the activation of the enzyme caspase -- a key player in a pathway leading to apoptos...Mechanism of hallucinogens' effects discovered
...cal that also activates 2AR receptors on the mouse neural machinery. Since the animals could not report the ...rote that "These studies identify the long-elusive neural and signaling mechanisms responsible for the unique effects of hallucinogens." They also concluded...Canadian study shows bilingualism has protective effect in delaying onset of dementia by four years
...ears of life. Cognitive reserve refers to enhanced neural plasticity, compensatory use of alternative brain regions, and enriched brain vasculature, all of which are thought to provide a general protective function against the onset of dementia symptoms. Now scientists with the Rotman Research Institute ...Brain studies reveal the mechanisms of the voluntary control of visual attention
... University have mapped the timing and sequence of neural activations that unfold in the brain when people f...s in regional blood flow associated with increased neural activity, the technology is "very limited as to the timing information it can provide," Woldorff sai...Patients with PTSD experience less pain sensitivity -- may be related to altered processing
...lands, and colleagues conducted a study to examine neural correlates of pain processing in patients with PTS...r reduced pain sensitivity in PTSD. The witnessed neural activation pattern is proposed to be related to altered pain processing in patients with PTSD," the ...How your brain helps you become a wine expert
...he added. This malleability of the brain is called neural plasticity....Genetically modified cells attack tumors
... first to provide evidence that such cells, called neural stem-progenitor cells (NSPCs), can be used to target solid tumors that have metastasized (spread from their original site), according to the researchers. During normal development NSPCs give rise to all the various types of cells in the brain. Mor...Stem cell activity deciphered in the aging brain
... the brain drain was due to a decreasing supply of neural stem cells in the aging hippocampus, said lead stu...hat in young rats, approximately 25 percent of the neural stem cells were actively dividing, but only 8 percent of the cells in middle-aged rats and 4 percent...Researchers identify genes that allow brain cancer-causing stem cells to resist treatment
...While great interest has followed the discovery of neural stem cells and their potential for someday treatin...adily distinguishing cancer stem cells from normal neural stem cells, which could lead to therapies targeting the cancer-causing cells without damaging health...New dyslexia theory blames 'noise'
...ntial, 30-year-old theory thatblamed dyslexia on a neural deficit in processing the fastsounds of language. Instead, the studies suggest that children with dyslexiahave bad filters for irrelevant data. As a result, they struggleto form solid mental categories for identifying letters andword sounds. Suc...Pioneers in field of functional genomics work toward gene therapy for vision defects
...ausal chain from the gene, to protein function, to neural signal. They are applying these lessons to other genetic defects that cause visual impairment. "We anticipate that our studies of the basic mechanisms controlling gene expression in the retina, and the structure/functional relationships among prote...Natural protein stops deadly human brain cancer in mice
...of proteins, bone morphogenic proteins, that cause neural stem-cell-like clusters to lose their stem cell properties, which in turn stops their ability to divide. First they pretreated human glioblastoma cells with bone morphogenic protein 4 (BMP4), then injected these treated cells into mouse brains. In m...Functional brain imaging insights from UC San Diego grad student
... Using this information to create accurate maps of neural activity with the highest possible spatial and tem...of the established Bayesian techniques for imaging neural activity. The paper took one of three 2006 Outstanding Student Paper Awards at NIPS, chosen from ...Regulatory pathway in brain development possible basis for malformations
...n development that sheds new light on how immature neural cells choose between proliferation and differentia...ified a genetic regulatory pathway that controls a neural precursor cell's decision to self-renew as a dividing precursor or differentiate into a non-dividing...The pain from fibromyalgia is real, researchers say
...sations normally. In people with fibromyalgia, the neural activity increased, says Daniel J. Clauw, M.D., director of the U-M Chronic Pain and Fatigue Research Center and professor of rheumatology at the U-M Medical School, and an author of the new paper. These studies indicate that fibromyalgia patients ha...Quest for better breast cancer drugs
...cers as well as diseases such as heart disease and neural and psychiatric diseases. Identifying which drugs have the best responses in particular patients would not only save lives but would also save the NHS money as treatment with expensive drugs can be tailor-made for whom it works....Blocking an inter-generational cycle of obesity
...ffect. "Evidence from our work suggests that the neural network, the pathway that regulates appetite and f...irth and for a short time after birth but once the neural connection is set up, the appetite regulation pattern becomes permanently set," Muhlhausler said. ...Inexpensive test detects H5N1 infections quickly and accurately
...man error--the researchers developed an artificial neural network trained to recognize the distinctive pattern indicative of H5N1. Automating the interpretation of MChip results could allow it to be used more readily by health workers at the site of possible flu outbreaks, notes Dr. Rowlen. "This new techn...