Genetically modified cells migrate to brain and treat neurodegeneration in St. Jude model
...lls to transport a "drug" to the site of the dying neural cells (cells that transmit impulses). This discovery occurred based on results of a laboratory study of the technique published by investigators at St. Jude Children's Research Hospital. A report on this work appears in the prepublication online issu...Going to extremes to improve human health
...nditions such as diabetes, involves uncovering the neural and vascular interactions in the skin during environmental heat stress. In the effort to understand why young women are more susceptible to fainting than men, he also studies how estrogen and progesterone influence blood pressure regulation. Minson i...Placebos can bring emotional relief
...e concept of placebo and its associated underlying neural processes." They also concluded that the placebo effect can be thought of "as a general process of modulation induced by the subjects' expectations, possibly using specific modulating systems."...Investigating 'brain shrinkage' in alcoholics
...bouts of drinking, dependence may ensue along with neural systems damage, commonly affecting frontal lobe based systems and their functions, which include decision making, inhibition, problem solving, and judgment. This is part of the dynamic course of alcoholism that likely contributes to its maintenance....Drinking for just eight weeks impairs learning and memory in mice
... months or more can produce permanent deficits and neural damage. A rodent study in the June issue of Alcoholism: Clinical & Experimental Research is the first to show that continuous drinking for as little as eight weeks can produce deficits in learning and memory that last up to 12 weeks after drinking...Mutation in mouse circulatory gene mimics a form of congenital heart disease
...ood vessels originated from defects in the cardiac neural crest cells, stem cells that migrate from regions ...all, the researchers demonstrated that the cardiac neural crest cells that originate in the brain do migrate to the heart and outflow tract areas; but, unlike...Depression is common in patients after heart attack, new Johns Hopkins study shows
...ion after heart attack as a complex interaction of neural hormones, biological changes and sensory perceptions that medicine has only begun to study and explain. "It is far more complex an issue than just being sad or feeling blue for a short period," he says. "What we're talking about here is a serious i...The anatomy of sarcasm: Researchers reveal how the brain handles this complex communication
...um, Shamay-Tsoory and his/her colleagues propose a neural network for processing sarcastic utterances: 1-The left hemisphere language cortices interpret the literal meaning of the utterance; 2-The frontal lobes and right hemisphere process the intentional, social and emotional context, identifying the con...Nature as important as nurture in developing ability for flexible self-control
...el is the first to offer an explanation of how the neural circuits that allow us to apply rules and strategi...ibility that the model will help us understand the neural basis of developmental disorders involving flexible cognitive control, such as ADHD and autism spect...News tips from The Journal of Neuroscience
...ns in the subthalamic nucleus (STN) show increased neural activity inParkinson's disease. Yet lesioning or high-frequency stimulation of the STN (HFSSTN) alleviates motor symptoms in parkinsonian patients. How does that work? In this week's Journal , Windels et al. approach the question by using microdialy...Babies' cries linked to their health
...as well as an increased tension and instability of neural control of the vocal tract. "Given the results of ...re noisy, broken-sounding cries that indicate poor neural control of the vocal track. While someone might be able to point out a noisy cry, there is little e...Sex differences in the human brain
... Yasmin Hurd 09.15 - 09.45 Arthur P Arnold: The neural origin of sex differences in the brain. Department of Physiological Sciences, UCLA, USA 09.45 - 10.15 Donald Pfaff: Differences in transcript levels in specific regions of male and female brains during the period of CNS sexual differentiation. ...Magnetic stimulation treatment for depression helping difficult-to-treat cases at UT Southwestern
... The problem in the past has been that generalized neural stimulation can cause significant side effects, su...ffects. "With magnetic stimulation, we can provide neural stimulation in a very specific, localized focal area, avoiding those parts of the brain that can cau...Study suggests antibiotic may limit or prevent vision problems caused by diabetes
...s," said Kyle Krady, Ph.D., assistant professor of neural and behavioral sciences, Penn State College of Med...ve death," said Steve Levison, Ph.D., professor of neural and behavioral sciences, Penn State College of Medicine, and professor of neurology and neuroscience...Insulin-producing cells from brain cursors
...cells derived from brain which usually mature into neural cells, and exposed them to a series of signals tha...s from a wide range of human stem cells, including neural stem cells and ES cells."...Study finds possible mechanism for link between sleep disturbances and metabolic syndrome
...ness, and appetite. Together, these alterations in neural andperipheral hormones suggest that a number of previously undetected braincircuits may exist that are common to sleep and eating. The mice with a mutation in the Clock gene fed a regular diet gained aboutas much weight as normal mice that were fed a...Feeling safe and secure? CUMC scientists find it's all in the caudoputamen
...rprise that we found that the safety sound reduces neural activity in the amygdala," Michael Rogan says. But Rogan and Kandel also found that the safety signal traveled through other, previously unknown circuits that lead to the brain's caudoputamen, a region known to be involved in motivation and reward. T...News tips from the Journal of Neuroscience
... Lee, and Jason W. Tarpley Rodents "freeze" when a neural conditioned stimulus (CS), such as a tone, is paired with an aversive unconditioned stimulus (US), such as an eyelid shock. This pavlovian fear conditioning requires the amygdala, particularly the lateral nucleus of the amygdala (LA), where the CSUS ...OHSU researchers demonstrate how Alzheimer's disease impacts important brain cell function
...chemical that bonds at nerve terminals for normal neural communication. The low levels of cellular ATP at nerve terminals may lead to the loss of synapses and synaptic function, and may ultimately cause cognitive decline in AD patients. To conduct this research, Reddy and his colleagues studied 36 brain ......a person learning a motor skill would engage their neural systems for movement planning and control, and that the subjects would construct a neural representation of the mechanical requirements of the task. "A powerful new idea in neuroscience link...